1.Studying on the platelet aggregation in patients undergoing cardiopulmonary bypass at Viet Dac hospital
Nga Thi Thien Ho ; Tu Anh Nguyen ; Nga Thi Nguyen
Journal of Medical Research 2007;47(1):19-23
Background: Cardiopulmonary bypass (CPB) may reduce the numbers of platelets and cause platelet function disorder. Postoperative bleeding is one of the most common complications in patients undergoing cardiac surgery. Objectives: (1) To study changes platelet count and platelet aggregation with ADP in patients undergoing CPB. (2) To identify the relationship between the postoperative bleeding and these parameters. Subjects and method: Crossectional descriptive study on 35 patients of three groups: congenital heart diseases, valvular heart diseases and coronary artery disease. Results: Platelet count and platelet aggregation with ADP reduce. Conclusion: There is a considerably change in the number of platelets and disturbance of platelet function in patients undergoing CPB. No remarkable evidence on relationship between posttoperative bleeding and above disorders.
Platelet Aggregation
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Cardiopulmonary Bypass
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2.Innovative data tools: a suite for managing peer outreach to key affected populations in Viet Nam
Nga Nguyen Thien ; Jacka David ; Van Hai Nguyen ; Trinh Nguyen Kieu ; Boisen Neil ; Neukom Josselyn
Western Pacific Surveillance and Response 2012;3(3):29-34
Problem: The paper tools used to monitor outreach work in all major cities in Viet Nam had substantial writing requirements for each contact with difficulty maintaining confidentiality. Action: This paper describes the development of a Unique Identifier Code (UIC), a field data collection notebook (databook)and a computer data entry system in Viet Nam. The databook can document 40 individual clients and has space forcommodity distribution, group contacts and needles/syringe collection for each month. Outcome: Field implementation trials of the UIC and databook have been undertaken by more than 160 peer outreachworkers to document their work with people who inject drugs (PWID) and sex workers (SW). Following an expanded trialin Hai Phong province, there have been requests for national circulation of the databook to be used by peer educators documenting outreach to PWID, SW and men who have sex with men. The standardized UIC and databook, in a variety of locally adapted formats, have now been introduced in more than 40 of the 63 provinces in Viet Nam. Discussion: This development in Viet Nam is, to our knowledge, the first example of the combination of a confidential UIC and an innovative, simple pocket-sized paper instrument with associated customized data-entry software for documenting outreach.
3.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.
4. In vivo anticancer activity of maesopsin 4-O-β-glucoside isolated from leaves of Artocarpus tonkinensis A. Chev. Ex Gagnep
Trinh Thi THUY ; Dao Duc THIEN ; Tran QUANG HUNG ; Nguyen Thanh TAM ; Nguyen Thi Hoang ANH ; Tran VAN SUNG ; Nguyen Thi NGA ; Nguyen Thi CUC ; Do Thi THAO ; Le Phuong MAI ; Domenico V. DELFINO
Asian Pacific Journal of Tropical Medicine 2016;9(4):351-356
Objective: To investigate the antitumor effect of maesopsin 4-O-β-glucoside (TAT2) isolated from the leaves of Artocarpus tonkinensis (A. tonkinensis) A. Chev. ex Gagnep. Methods: The antitumor activity of TAT2 was evaluated in Lewis lung carcinoma (LLC) tumor-bearing mice. BALB/c mice had tumors induced by implantation with 2 × 10
5.Isolation and toxicity of Xanthomonas oryzae pv. oryzae in rice and a collection of phages against the pathogen
Ngoc Quynh Anh Pham ; Vo Thanh Phuc ; Pham Do Tra My ; Le Thi My Duyen ; To Hue Ngoc ; Nguyen Minh Thien ; Nguyen Hai Duong ; Le Thi Thuy Tien ; Le Phi Nga ; Hoang Anh Hoang
Malaysian Journal of Microbiology 2024;20(no.1):15-23
Aims:
The objective of the study was to isolate bacteriophages and conduct a comprehensive analysis of their potential against Xanthomonas oryzae pv. oryzae (Xoo) strains in the Mekong Delta, Vietnam.
Methodology and results:
Twelve Xoo strains were isolated from rice fields located in the Mekong Delta, Vietnam. Among these strains, three strains Xoo L019, L020 and L024, showed the highest disease index of bacterial blight. Four
phages specific to Xoo were isolated from soil, water and leaf samples, and their morphologies were determined. In a test against 12 Xoo strains, phage L541, MLA23 or W41 could infect 10 of the 12 Xoo strains, while phage LBH01 could infect 8 of the 12 Xoo strains. The stability of the phages to pH, organic solvents, UV-A and UV-B was also evaluated.
Conclusion, significance and impact of study
The initial characterization of the phages indicates their potential as biocontrol agents against bacterial blight in rice. The study is one of the very first studies about Xoo phages in rice in Vietnam.