1.Acquired, Bilateral Nevus of Ota-like Macules (ABNOM) Associated with Ota's Nevus: Case Report.
Journal of Korean Medical Science 2004;19(4):616-618
Ota's nevus is mongolian spot-like macular blue-black or gray-brown patchy pigmentation that most commonly ocurrs in areas innervated by the first and second division of the trigeminal nerve. Acquired, bilateral nevus of Ota-like macules (ABNOM) is located bilaterally on the face, appears later in life, is blue-brown or slate-gray in color. It is not accompanied by macules on the ocular and mucosal membranes. There is also debate as to whether ABNOM is part of the Ota's nevus spectrum. We report an interesting case of ABNOM associated with Ota's nevus. A 36-yr-old Korean women visited our clinic with dark bluish patch on the right cheek and right conjunctiva since birth. She also had mottled brownish macules on both forehead and both lower eyelids that have developed 3 yr ago. Skin biopsy specimens taken from the right cheek and left forehead all showed scattered, bipolar or irregular melanocytes in the dermis. We diagnosed lesion on the right cheek area as Ota's nevus and those on both forehead and both lower eyelids as ABNOM by clinical and histologic findings. This case may support the view that ABNOM is a separate entity from bilateral Ota's nevus.
Adult
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Biopsy
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Face/pathology
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Female
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Humans
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Melanocytes/cytology
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Nevus of Ota/diagnosis/*pathology
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Nevus, Pigmented/diagnosis/*pathology
2.A new classification of nevus of Ota.
Wen-hui HUANG ; Hong-wei WANG ; Qiu-ning SUN ; Hong-zhong JIN ; Yue-hua LIU ; Dong-lai MA ; Ya-gang ZUO ; He-yi ZHENG ; Kuo WAN ; Quan JING ; Yong-liang ZHAO
Chinese Medical Journal 2013;126(20):3910-3914
BACKGROUNDThe nevus of Ota, is a common benign pigmentary dermatosis, mainly involve innervation area of first and second branch of trigeminal nerve. The classification of nevus of Ota was proposed by Tanino, based on 26 cases of nevus of Ota from 1937 to 1940. Studies about its classification are rarely seen in last 70 years, while it is still practical today.
METHODSBased on the clinical photographs, 1079 consecutive patients with nevus of Ota were verified and reclassified according to the innervation areas of the trigeminal nerve branches.
RESULTSIn these 1079 cases, 866 patients were in line with Tanino's classification (80.26%), and 213 patients were not (19.74%). We put forward a new clinical classification (Peking Union Medical College Hospital classification, PUMCH classification) of nevus of Ota based on the innervation area of the trigeminal nerve branches, composed of 5 types and 14 subtypes. The 5 types were as follows: Type I - pigmentation maculeses involving the innervation area of one of the three trigeminal nerve branches, of which there were 424 cases (39.3%), comprising 6 subtypes; Type II - pigmentation macules involving the innervation area of two branches of the three trigeminal nerve branches, of which there were 221 cases (20.48%), comprising 4 subtypes; Type III - pigmentation macules involving the innervation area of all three trigeminal nerve branches, of which there were 361 cases (33.45%), comprising 2 subtypes; Type IV - bilateral type, in which the pigmentation macules involves the bilateral cheek, of which there were 63 cases (5.84%), comprising 2 subtypes; and Type V - complications occurred in the patient, of which there were 10 cases (0.93%).
CONCLUSIONThe new classification of nevus of Ota is based on the innervation area of the trigeminal nerve branches, and it covers all types of Tanino's classifications; on that basis, some new types and subtypes are brought in and cover almost every clinical condition.
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Middle Aged ; Nevus of Ota ; classification ; diagnosis ; Trigeminal Nerve ; pathology ; Young Adult
3.Meningeal melanocytoma with nevus fuscoceruleus ophthalmomaxillaris: report of a case.
Chun WU ; Hai WANG ; Qun-li SHI ; Heng-hui MA ; Zhen-feng LU
Chinese Journal of Pathology 2011;40(3):194-195
Adult
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Diagnosis, Differential
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Humans
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MART-1 Antigen
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metabolism
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Magnetic Resonance Imaging
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Male
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Medulloblastoma
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metabolism
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pathology
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Melanocytes
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pathology
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Melanoma
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diagnosis
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metabolism
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pathology
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surgery
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Melanoma-Specific Antigens
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metabolism
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Meningeal Neoplasms
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diagnosis
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metabolism
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pathology
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surgery
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Neoplasms, Multiple Primary
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diagnosis
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metabolism
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pathology
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surgery
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Neurilemmoma
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metabolism
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pathology
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Nevus of Ota
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diagnosis
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metabolism
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pathology
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surgery
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S100 Proteins
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metabolism
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Skin Neoplasms
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diagnosis
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metabolism
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pathology
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surgery
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Vimentin
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metabolism