No abstract available.
Nevus of Ota* ; Nevus* ; Recurrence* ; Stem Cells*

No abstract available.
Nevus of Ota* ; Nevus* ; Recurrence* ; Stem Cells*

The nevus of Ota is a benign nevus characterized by the deposition of pigment in an area of distribution of the first and second branches of the trigeminal nerve. In general it rarely causes ophthalmological problems. We experienced a 23-year-old male patient who complained sudden visual loss in the left eye with the characteristics of the nevus of Ota. On examination we found the altitudinal field defect which we believe is an unusual finding of the nevus of Ota.
Humans ; Male ; Nevus ; Nevus of Ota* ; Trigeminal Nerve ; Young Adult

Benign pigmented lesions derived from dermal melanocytes include the Mongolian spot, the nevi of Ota and Ito, and the blue nevus. The nevus of Ito differs from the nevus of Ota by its location in the supraclavicular, scapular and deltoid regions. It occurs rarely in association with bilateral nevus of Ota. We present a 70 years old male, showing extensive involvement of dermal melanocytic nevi, so called bilateral nevus of Ota associated with bilateral nevus of Ito.
Aged ; Humans ; Male ; Melanocytes ; Mongolian Spot ; Nevus of Ota* ; Nevus* ; Nevus, Blue ; Nevus, Pigmented

BACKGROUND: Until recently, the removal of melanocytic nevi has been performed with a CO2 laser or Er:YAG laser. These lasers have been useful for removing affected spots. However, enlargement of spots or some sequelae, including depressed or hypertrophic scars, could develop as unwanted results. The Q-switched Nd:YAG laser has been used to remove deep-seated melanocytes, such as Ota nevus or tattoos. However, there have been no previous experiments performed to test the efficacy and safety of this laser treatment for melanocytic nevi. OBJECTIVE: The objective of this study was to investigate the efficacy and safety of the 1,064 nm Q-switched Nd:YAG laser for removing melanocytic nevi, including congenital nevomelanocytic and acquired nevomelanocytic nevi. METHODS: Two thousand and sixty four Korean patients with small melanocytic nevi were treated with a Q-switched Nd:YAG laser from 2005 to 2009. High-resolution photographs were taken in identical lighting and positions before and after the six weeks of treatment to observe the procedural efficacy. RESULTS: About 70% of the nevi treated using a 1,064 nm Q-switched Nd:YAG laser were completely removed after one session. The other 30% were completely treated within three sessions. The appearance of sequelae such as hollow scars noticeably decreased compared to the results seen in CO2 or Er:YAG laser treatments. CONCLUSION: Use of the 1,064 nm Q-switched Nd:YAG laser is a safe and effective treatment modality for melanocytic nevi.
Cicatrix ; Cicatrix, Hypertrophic ; Humans ; Lasers, Gas ; Light ; Lighting ; Melanocytes ; Nevus ; Nevus of Ota ; Nevus, Pigmented

Dermal melanocytosis includes Mongolian spot, nevi of Ota and Ito, dermal melanocytic harnartoma, and blue nevus. Nevi of Ota may be respectively associated with Mongolian spot, blue nevi and unilateral or bilateral nevi of Ito. We present a case, a 24 year-old female, who had bilaterally brownish or slatebluish pigmented patches on the face, sclera, neck, anterior chest, deltoid, supraclavicular, scapular, back and sacrococcygeal area. And also she had a bluish, bean-sized nodule on her left mid-back. It is likely that this case may be considered as an extremely extensive case of pig:m.entary anomaly, associating aberrant and persistent mongolian spots, extensive nevus of Ito, bilateral nevus of Ota and blue nevus. To our knowledges it seems that such case has not previously been reported in Korean literature.
Female ; Humans ; Mongolian Spot ; Neck ; Nevus ; Nevus of Ota ; Nevus, Blue ; Sclera ; Thorax ; Young Adult

Dermal melanocytosis is characterized by the presence of ectopic melanocytes in the dermis. The most common forms include the Mongolian spot, blue nevus, nevus of Ota, and nevus of Ito. Some types of dermal melanocytosis do not fit into any of these morphologic categories, however. Our case demonstrated an extensive amount of uniform deep blue patches of nevi with unilateral distribution on the left face, neck, chest, shoulder, and back. On histopathologic examination, a number of elongated melanocytes scattered throughout the dermis were found. We herein report a case of congenital unilateral dermal melanocytosis.
Dermis ; Melanocytes ; Mongolian Spot ; Neck ; Nevus ; Nevus of Ota ; Nevus, Blue ; Shoulder ; Thorax

PURPOSE: To investigate the clinical features of the nevus of Ota in the Korean population. METHODS: A retrospective chart review of the medical records from 94 patients (100 eyes), diagnosed to have a nevus of Ota from September 2005 to February 2010, was performed. RESULTS: The mean age of detection of a nevus of Ota was 8 months, and the mean extent of the nevus was 253 degrees, which covered more than 2 quadrants in most cases. The patients with a faint nevus tended to be younger. Pigmentation did not reach the fornix, but the limbus was mostly pigmented. Combined conjunctival pigmentation was observed in 61.7% of cases. The pigmentation was significantly associated with a greater extent of the nevus. Iris pigmentation was demonstrated in 98.7% of cases. CONCLUSIONS: The clinical features of nevi of Ota were diverse regarding the location, extent, and color of the lesion. Conjunctival pigmentation was associated with the extent of the nevus. Iris pigmentation was revealed in almost all cases; therefore, this feature had the diagnostic value for a nevus of Ota. Young patients with a nevus of Ota may mimic osteogenesis imperfecta, which necessitates careful consideration upon differential diagnosis.
Diagnosis, Differential ; Humans ; Hydrazines ; Iris ; Medical Records ; Nevus ; Nevus of Ota ; Osteogenesis Imperfecta ; Pigmentation ; Retrospective Studies

PURPOSE: To report a case of cosmetically successful treatment of nevus of Ota performed by scleral painting and scleral allograft transplantation. METHODS: Scleral painting and allograft transplantation were done in a 28-year-old woman who had cosmetic problem due to nevus of Ota, and she was followed up for 5 months postoperatively. RESULTS: The patient had no specific postoperative complication and was satisfied with the surgical results. CONCLUSIONS: For patients of nevus of Ota who have not been treated successfully, scleral painting and allograft transplation can be an effective cosmetic treatment.
Adult ; Allografts ; Female ; Humans ; Nevus of Ota* ; Nevus* ; Paint ; Paintings ; Postoperative Complications

BACKGROUND: The Q-switched ruby laser has recently shown that it can remove tattoos with-out scarring. Therefore the Q-switched ruby laser is expected to be effective in the treatment of nevus of Ota, which contains pigmented cells in the dermis. OBJECTIVE: The purpose of this study is to evaluate the efficacy of Q-switched ruby laser in the treatment of nevus of Ota. METHODS: Twenty-five patients (6 men, 19 women) with nevus of Ota on the face were treat-ed. The age of the patients ranged from 3 to 62 years. The energy fluence used varied from 6 to 8.5 J/cm². Treatment intervals ranged from 1 to 3 months, and the number of treatments ranged from 2 to 9. Photographs were taken of all patients before and on every return visit. The photographs were then compared with each other. After completion of treatment, we evaluated some parameters including the extent of pigment-free area within the skin lesions (score 0-4), degree of lightening in the remaining skin lesions (score 0-3), and patient's own or their parents' opinions on the result of treatment (score 0-3). The scores of the above three parameters were added and the resulting scores were designated as excellent (score 9-10), good (score 7-8), moderate (score 5-6) and poor (score 0-4). RESULTS: Excellent treatment response (score 9-10) was obtained in 6 of the 25 patients. In all patients disappearance of pigmentation on a 40 percent or larger area was seen. One month after completion of treatment, the remaining lesion size was less than 40 percent of the original lesion in 21 (84.0%) patients. The degree of lightening in the remaining lesion was marked (score 3) in 22 (88%) patients. No scarring was noted following treatment. Transient hyperpigmentation was noted in 7 patients, and transient hypopigmented areas were noted in one patient. CONCLUSION: Q-switched ruby laser appears to be an effective and safe modality for the treatment of nevus of Ota.
Cicatrix ; Dermis ; Humans ; Hyperpigmentation ; Lasers, Solid-State* ; Male ; Nevus of Ota* ; Nevus* ; Pigmentation ; Skin