1.Early Involvement of Hair Melanocytes Prior to Epidermal Melanocytes in the Progress of Halo Nevus.
Korean Journal of Dermatology 2016;54(2):151-153
No abstract available.
Hair*
;
Melanocytes*
;
Nevus, Halo*
2.Spontaneous Re-pigmentation of Vitiligo Following Excision of Halo Congenital Melanocytic nevi: An Interesting Case Report
Anil Prakash Gosavi ; Ravindranath Brahmadeo Chavan ; Neelam Bhatt ; Darshana Rajendra Kundale
Malaysian Journal of Dermatology 2022;49(Dec 2022):25-27
Summary
Halo nevi (HN) are benign skin lesion that represent melanocytic nevi in which an inflammatory
infiltrate develops, resulting in zone of depigmentation around nevus. Although Sutton originally
described the lesion in 1916 as leukoderma acquista centrifugum, the lesions were noted earlier as
evidenced in the painting by Matthias Grunwald cica 1512-1516. The prevalence of HNs in the general
population is 1%, and HNs usually appear in childhood or early adulthood. Up to 26% of patients
with HN have vitiligo, but in very few instances is there an association of HN around congenital
melanocytic nevi (CMN) and vitiligo. The exact mechanisms responsible for the development of
vitiligo and HN and its resolution are unknown. One of the most accepted hypotheses considers that
both phenomena are a result of a self-limited immunologic response to pigmented cells, either in the
“normal” skin or within the melanocytic lesion. Hereby we present a rare case report of a girl with
halo CMN and infraorbital vitiligo. The halo CMN was excised which was followed by spontaneous
improvement of vitiligo.
Vitiligo
;
Nevus, Halo
3.Development of Halo Nevus Around Nevus Spilus as a Central Nevus, and the Concurrent Vitiligo.
Yoon Young KIM ; Mi Yeon KIM ; Tae Yoon KIM
Annals of Dermatology 2008;20(4):237-239
Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of the upper dermis in the depigmented lesions. We report here on a 13-year-old boy who showed a depigmented zone around a nevus spilus on the right side of his neck with simultaneous vitiligo lesions on the face.
Adolescent
;
Dermis
;
Humans
;
Neck
;
Nevus
;
Nevus, Halo
;
Nevus, Pigmented
;
Vitiligo
4.Halo Congenital Nevus Followed by Periocular Vitiligo.
Sang Don YOON ; Sung Ae KIM ; Kyu Suk LEE ; Jae We CHO
Korean Journal of Dermatology 2013;51(4):280-283
Halo nevus is a pigmented nevus surrounded by acquired round depigmentation. Depigmentation appears mostly around several types of pigmented lesions, such as acquired nevus, congenital nevus, blue nevus and Spitz nevus. In contrast, it is rare that depigmentation develops around a congenital nevus. While the precise etiology of halo nevus and vitiligo remains uncertain, several theories suggest that both phenomena result from an immunologic reaction to melanocytes by CD8 + T cell. We report a case of halo congenital nevus in the arm, which is followed by periocular vitiligo. This is the third case in Korean dermatological literature.
Arm
;
Melanocytes
;
Nevus
;
Nevus, Blue
;
Nevus, Epithelioid and Spindle Cell
;
Nevus, Halo
;
Nevus, Pigmented
;
Vitiligo
5.A Case of Halo Congenital Nevus.
Jae Hoon JUNG ; Sung Hwan CHOE ; You Chan KIM ; Hyang Joon PARK ; Yong Woo CINN
Korean Journal of Dermatology 2001;39(7):844-846
A halo nevus is a pigmented nevus surrounded by a depigmented zone. It usually occurs in childhood or adolescence. Depigmented zone may form around a variety of acquired melanocytic lesions of neuroectodermal origin, including nevocellular nevi, blue nevi, spindle and epithelioid nevi, primary and metastatic melanomas, and neurofibromas. The occurrence of a halo around congenital melanocytic nevi has rarely been reported. We report a case of halo congenital nevus in a 11-year-old girl.
Adolescent
;
Child
;
Female
;
Humans
;
Melanoma
;
Neural Plate
;
Neurofibroma
;
Nevus*
;
Nevus, Blue
;
Nevus, Halo
;
Nevus, Pigmented
6.Halo Congenital Nevus Associated with Extralesional Vitiligo.
Ki Hun SONG ; Yong Sun CHO ; Su Ran HWANG ; Han Uk KIM ; Seok Kweon YUN ; Jin PARK
Korean Journal of Dermatology 2012;50(1):43-48
Halo nevus is a pigmented nevus surrounded by a round or oval depigmentation. Of patients with halo nevus, 18 to 26% patients have vitiligo, either involving the nevus or at a distant site. While the exact etiology of halo formation and vitiligo is unknown, several theories suggest that common immunologic mechanisms are involved in the destruction of melanocytes of both phenomena. Unlike common melanocytic nevus, congenital nevus associated with both halo formation and concurrent extralesional vitiligo is very uncommon and only one case has been reported in the Korean dermatological literature. A 19-year-old female presented with surrounding depigmentation around a congenital hairy nevus on the left forearm. Simultaneously, vitiligo appeared on the lowerabdomen and surrounding regions of both areola. The halo depigmented lesion around congenital nevus and the periareolar vitiliginous lesion shared some histological and immunohistochemical features. These findings further support common immunological mechanisms of pigment destruction in both phenomena.
Female
;
Forearm
;
Humans
;
Melanocytes
;
Nevus
;
Nevus, Halo
;
Nevus, Pigmented
;
Vitiligo
;
Young Adult
7.Halo Dermatitis Around Junctional Nevus.
Chi Yeon KIM ; Kyeong Tae KIM ; Chee Won OH
Korean Journal of Dermatology 2006;44(10):1259-1261
Halo dermatitis (Meyerson's nevus) is an inflammatory, eczematous eruption usually encircling a preexisting melanocytic nevus. Spontaneous healing occurs within several weeks or months and is never concurrent with regression of the central nevus, in contrast to halo nevus (Sutton's nevus). Although halo dermatitis is often associated with central melanocytic nevi, pathogenesis leading to the morphological change of this disorder remains obscure. Herein, we report a case of a 23-year-old female who developed an eczematous halo reaction surrounding the junctional nevi.
Dermatitis*
;
Eczema
;
Female
;
Humans
;
Nevus*
;
Nevus, Halo
;
Nevus, Pigmented
;
Young Adult
8.Halo Nevus Arising from Congenital Melanocytic Nevus Featuring an Early Onset Vitiligo.
Osung KWON ; Yongwoo CHOI ; Hyun CHUNG ; Joonsoo PARK
The Ewha Medical Journal 2017;40(4):155-158
Halo nevus and vitiligo are known to be associated with immunologic defect that result in typical skin lesions. Random shapes and sizes of whitish patches, depending on the type, are featured in vitiligo. Halo, on the other hand, presents by surrounding the previous pigmented lesion leaving a whitish-halo-like appearance. The mechanisms underlying these entities remain to be elucidated. Various immunological responses along with biomechanical activities suggest causal relationship between the two diseases. A 6-year-old male patient was recently presented with multiple whitish patches on the various parts of the body in a Koebner phenomenon manner. A noticeable hairy congenital melanocytic nevus surrounded a well-demarcated halo of depigmentation was also observed. Clinical and pathological findings were conclusive of as halo nevus with multiple concurrent vitiligo. The pathogenic relationship between the two entities must be underlined since the nature of disease progression is associated and the respective management may also be altered accordingly.
Child
;
Disease Progression
;
Hand
;
Humans
;
Male
;
Nevus, Halo*
;
Nevus, Pigmented*
;
Skin
;
Vitiligo*
9.Halo Dermatitis Around a Compound Nevus.
Young Hun CHO ; Jin Wook LEE ; Sang Gun PARK ; Min Geol LEE
Korean Journal of Dermatology 2003;41(9):1261-1263
Halo dermatitis was first described as a halo-shaped eczematous change around a nevocellular nevus. However, other cases developed around various kinds of lesions including seborrheic keratosis or lentigo were reported later on, so it is now considered not to be specific for melanocytes or nevus cells. It has never been reported to be associated with regression of central lesion, in contrast to halo nevus. We report a case of halo dermatitis developed around a compound nevus in a 20-year-old male patient. On histopathologic examination, the central lesion was a compound nevus and the surrounding lesion was consistent with chronic eczematous dermatitis.
Dermatitis*
;
Eczema
;
Humans
;
Keratosis, Seborrheic
;
Lentigo
;
Male
;
Melanocytes
;
Nevus*
;
Nevus, Halo
;
Young Adult
10.A Case of Molluscum Contagiosum Occuring in a Soft Fibroma.
Jung Hoon LEE ; Bo Kyung KOH ; Jin Wou KIM
Korean Journal of Dermatology 2005;43(4):553-554
Molluscum contagiosum (MC) is a skin infection caused by a poxvirus, which is easily transmitted by direct skin to skin contact. MC is rarely associated with other skin diseases, including epidermal cysts, melanocytic nevus, halo nevus, soft fibroma or condyloma. The occurrence of MC on a soft fibroma is so rare that only three cases have been described so far. Here, we report an interesting a case of a solitary MC associated with soft fibroma occurring on the right popliteal fossa of a 6-year-old girl.
Child
;
Epidermal Cyst
;
Female
;
Fibroma*
;
Humans
;
Molluscum Contagiosum*
;
Nevus, Halo
;
Nevus, Pigmented
;
Skin
;
Skin Diseases