1.Artificial External Glottic Device for Passive Lung Insufflation.
Dong Hyun KIM ; Seong Woong KANG ; Yoon Ghil PARK ; Won Ah CHOI ; Hye Ree LEE
Yonsei Medical Journal 2011;52(6):972-976
PURPOSE: For patients with neuromuscular disease, air stacking, which inflates the lungs to deep volumes, is important for many reasons. However, neuromuscular patients with severe glottic dysfunction or indwelling tracheostomy tubes cannot air stack effectively. For these patients, we developed a device that permits deep lung insufflations substituting for glottic function. MATERIALS AND METHODS: Thirty-seven patients with bulbar-innervated muscle weakness and/or tracheostomies were recruited. Twenty-three had amyotrophic lateral sclerosis, and 14 were tetraplegic patients due to cervical spinal cord injury. An artificial external glottic device (AEGD) was used to permit passive deep lung insufflation. In order to confirm the utility of AEGD, vital capacity, maximum insufflation capacity (MIC), and lung insufflation capacity (LIC) with AEGD (LICA) were measured. RESULTS: For 30 patients, MICs were initially zero. However, with the use of the AEGD, LICA was measurable for all patients. The mean LICA was 1,622.7+/-526.8 mL. Although MIC was measurable for the remaining 7 patients without utilizing the AEGD, it was significantly less than LICA, which was 1,084.3+/-259.9 mL and 1,862.9+/-248 mL, respectively (p<0.05). CONCLUSION: The AEGD permits lung insufflation by providing deeper lung volumes than possible by air stacking.
Adult
;
Aged
;
Female
;
Forced Expiratory Flow Rates/physiology
;
Humans
;
Insufflation/*instrumentation/methods
;
Male
;
Middle Aged
;
Neuromuscular Diseases/*physiopathology/therapy
;
*Ventilators, Mechanical
;
Vital Capacity/physiology
;
Young Adult
2.A Case of Sheehan's Syndrome that Manifested as Bilateral Ptosis.
Journal of Korean Medical Science 2011;26(4):580-582
Hypothyroidism can cause a variety of signs and symptoms of the neuromuscular system. However, ptosis in a patient with hypothyroidism is very rare. We report here on a case of central hypothyroidism that was due to Sheehan's syndrome and it manifested as bilateral ptosis in a 51-yr-old woman. She complained of exertional dyspnea and weakness. About 25-yr ago, she had a history of severe postpartum vaginal bleeding. The laboratory studies demonstrated hypopituitarism with secondary hypothyroidism. The ptosis was improved by replacement of thyroid hormone. Hypothyroidism should be considered in the differential diagnosis of patients who manifest with ptosis and that prompt replacement of hormone can lead to a complete recovery.
Blepharoptosis/complications/*diagnosis/drug therapy
;
Electromyography
;
Female
;
Glucocorticoids/therapeutic use
;
Humans
;
Hypopituitarism/complications/*diagnosis/drug therapy
;
Hypothyroidism/complications
;
Magnetic Resonance Imaging
;
Middle Aged
;
Muscular Diseases/etiology
;
Neuromuscular Junction/physiopathology
;
Prednisolone/therapeutic use
;
Thyroxine/therapeutic use