1.Neuroleptic malignant syndrome.
Journal of Korean Neuropsychiatric Association 1993;32(4):472-483
No abstract available.
Neuroleptic Malignant Syndrome*
2.A Case of Neuroleptic Malignant Syndrome (NMS) with Myoglobulinemic Acute Renal Failure and Lithium Intoxication due to Lithium-olanzapine Combination.
Won Taek OH ; Chi Hoon MAENG ; Mi Na PARK ; Sun Young CHOI ; Kyung Hwan JEONG ; Ju Young MOON ; Tae Won LEE ; Cheon Gyu IHM ; Sang Ho LEE
Korean Journal of Nephrology 2006;25(5):835-839
We report a patient developed neuroleptic malignant syndrome (NMS) with myoglobulinemic acute renal failure and lithium intoxication due to lithium-olanzapine combination, who was successfully treated by hemodiafiltration. A 34-year-old woman with a 14-year history of bipolar disorder had been treated with lithium-olanzapine during last four days. She was admitted to our hospital for muscular rigidity, hyperthermia and altered consciousness. On admission, rhabdomyolsis was demonstratd by biochemical methods and serum level of lithium was 3.78 mEq/L which was far above toxic level. After the diagnosis of NMS with acute renal failure and lithium intoxication, olanzapine and lithium were discontinued and conservative measures and continuous venovenous hemodiafiltration were instituted. She recovered without any neurologic sequelae.
Female
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Humans
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Neuroleptic Malignant Syndrome
3.A Case mimicking Neuroleptic Malignant Syndrome associated with Levodopa Withdrawal in Parkinson's Disease.
Hee Jun PARK ; Tae Hyung KIM ; Jung Eun KIM ; Bo Ram LEE ; Soo Joo LEE ; Gun Sei OH
Journal of the Korean Neurological Association 2005;23(5):721-723
No abstract available.
Levodopa*
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Neuroleptic Malignant Syndrome*
;
Parkinson Disease*
4.Neuroleptic Malignant Syndrome Caused by Long Term Intake of Haloperidol.
Jae Hoon JO ; Hyung Jong PARK ; Su Sin PARK ; Yeon Soo HA ; Hak Seung LEE ; Hyun Young PARK ; Hyuk CHANG ; Yo Sik KIM ; Kwang Ho CHO
Journal of the Korean Neurological Association 2011;29(3):214-215
Neuroleptic malignant syndrome (NMS) is a fatal complication most often caused by an adverse reaction to neuroleptic or antipsychotic drugs, and is mostly brought out in the initial stage of medication. Late onset NMS after long term intake of neuroleptics is uncommon, and the neurochemical mechanism is undiscovered. We report a patient of late onset NMS after a long term intake of haloperidol who was successfully treated with dantrolene and bromocriptine.
Antipsychotic Agents
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Bromocriptine
;
Dantrolene
;
Haloperidol
;
Humans
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Neuroleptic Malignant Syndrome
5.Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone.
Jeong Min KIM ; Soon Tae LEE ; Eun Cheol SONG ; Keun Hwa JUNG ; Dong In SINN ; Hakjae CHUNG ; Kon CHU ; Manho KIM
Journal of Clinical Neurology 2007;3(3):165-167
Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here we present a case of 19-year-old man who experienced serotonin syndrome caused by sertraline intake, and consecutive neuroleptic malignant syndrome by risperidone. This case suggests that these two syndromes can be concomitantly induced in some patients who are susceptible to these drugs. Clinicians may have to pay close attention to this problem when prescribing drugs to patients who previously showed sensitivity to CNS-acting drugs.
Antipsychotic Agents
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Humans
;
Neuroleptic Malignant Syndrome
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Risperidone*
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Serotonin Syndrome
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Sertraline*
;
Young Adult
6.Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone.
Jeong Min KIM ; Soon Tae LEE ; Eun Cheol SONG ; Keun Hwa JUNG ; Dong In SINN ; Hakjae CHUNG ; Kon CHU ; Manho KIM
Journal of Clinical Neurology 2007;3(3):165-167
Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here we present a case of 19-year-old man who experienced serotonin syndrome caused by sertraline intake, and consecutive neuroleptic malignant syndrome by risperidone. This case suggests that these two syndromes can be concomitantly induced in some patients who are susceptible to these drugs. Clinicians may have to pay close attention to this problem when prescribing drugs to patients who previously showed sensitivity to CNS-acting drugs.
Antipsychotic Agents
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Humans
;
Neuroleptic Malignant Syndrome
;
Risperidone*
;
Serotonin Syndrome
;
Sertraline*
;
Young Adult
8.A Case of Catatonia and Neuroleptic Malignant Syndrome Probably Associated with Antipsychotic in Korea.
Ho Dong CHOI ; Kyoung Keun KIM ; Bon Hoon KOO
Psychiatry Investigation 2011;8(2):174-177
Several studies have reported on catatonia caused by the use of antipsychotic drugs and on the association between catatonia and neuroleptic malignant syndrome (NMS), but none has reported such a case in Korea. Here, we report the case of a 20-year-old woman whose catatonia and NMS appeared associated with the administration of an atypical antipsychotic drug. We discuss the association between NMS and catatonia due to neuroleptic use.
Antipsychotic Agents
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Catatonia
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Female
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Humans
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Korea
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Neuroleptic Malignant Syndrome
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Young Adult
9.Recurrent Idiopathic Catatonia: Implications beyond the Diagnostic and Statistical Manual of Mental Disorders 5th Edition.
Stanley N CAROFF ; Irene HURFORD ; Henry R BLEIER ; Gregg E GORTON ; E Cabrina CAMPBELL
Clinical Psychopharmacology and Neuroscience 2015;13(2):218-221
We describe a case of recurrent, life-threatening, catatonic stupor, without evidence of any associated medical, toxic or mental disorder. This case provides support for the inclusion of a separate category of "unspecified catatonia" in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) to be used to classify idiopathic cases, which appears to be consistent with Kahlbaum's concept of catatonia as a distinct disease state. But beyond the limited, cross-sectional, syndromal approach adopted in DSM-5, this case more importantly illustrates the prognostic and therapeutic significance of the longitudinal course of illness in differentiating cases of catatonia, which is better defined in the Wernicke-Kleist-Leonhard classification system. The importance of differentiating cases of catatonia is further supported by the efficacy of antipsychotics in treatment of this case, contrary to conventional guidelines.
Antipsychotic Agents
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Catatonia*
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Classification
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Diagnostic and Statistical Manual of Mental Disorders*
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Mental Disorders
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Neuroleptic Malignant Syndrome
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Schizophrenia
;
Stupor
10.Rhabdomyolysis Associated with Ziprasidone.
Young Kyung SUNWOO ; Sang Hun LEE ; Min Hee KANG ; Chul Eung KIM ; Jeong Seop LEE ; Jae Nam BAE
Korean Journal of Psychopharmacology 2007;18(3):181-184
We describe a case report of a young male patient with rhabdomyolysis associated with the use of atypical antipsychotic medication ziprasidone. A 23-year-old male was diagnosed with psychotic disorder not otherwise specified and treated with ziprasidone 120 mg a day. On hospital day 6, the patient developed acute dystonia. On day 8, the serum creatine kinase (CK) level was markedly elevated up to 53,880 IU/L, and a white blood cell (WBC) count was 10,500 cells/microliter. No other diagnostic criteria for neuroleptic malignant syndrome (NMS) were present. On discontinuation of the drug, serum CK concentrations returned to normal within 10 days. Atypical NMS should be considered when patients was treated with novel atypical antipsychotics who develop isolated serum CK elevation.
Antipsychotic Agents
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Creatine Kinase
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Dystonia
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Humans
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Leukocytes
;
Male
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Neuroleptic Malignant Syndrome
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Psychotic Disorders
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Rhabdomyolysis*
;
Young Adult