Schwannoma in colorectum is a rare subepithelial polyp of mesenchymal origin, which is derived from the neural sheath, and most of reported cases were removed surgically. We, herein, describe two cases of schwannoma of the cecum, which were removed by endoscopic mucosal resection. A 34-year-old man and a 62-year-old man presented with abdominal discomfort and bowel habit change. The patients were diagnosed with a subepithelial tumor in the cecum on colonoscopy and underwent endoscopic mucosal resection under a tentative impression as neuroendocrine tumor, such as carcinoid tumor. Histopathology and immunohistochemistry confirmed the colonic lesion to be a benign schwannoma.
Carcinoid Tumor ; Cecum ; Colon ; Colonoscopy ; Humans ; Immunohistochemistry ; Neurilemmoma ; Neuroendocrine Tumors ; Polyps

Carcinoid tumors have been described in almost every organ and may affect virtually every body system. Cardiac involvement manifesting as right-sided valvular disease is characteristic of the carcinoid heart disease. Myocardial metastasis is an unusual manifestation of carcinoid heart disease and it was manifested as a mass lesion in the previous reports. We observed a myocardial metastasis of carcinoid tumor manifesting as diffusely infiltrative pattern.
Carcinoid Heart Disease* ; Carcinoid Tumor* ; Neoplasm Metastasis

Adult ; Cranial Nerve Neoplasms ; diagnosis ; Facial Nerve ; pathology ; Female ; Glomus Jugulare Tumor ; diagnosis ; Humans ; Neurilemmoma ; diagnosis

Adult ; Carotid Body Tumor ; complications ; Female ; Glomus Jugulare Tumor ; complications ; Humans

Carotid Body Tumor ; complications ; Female ; Glomus Jugulare Tumor ; complications ; Humans ; Middle Aged ; Paraganglioma ; complications

Somatostatin analogue is useful in carcinoid crisis for symptom control. Optimal dosing of somatostatin analogues for carcinoid symptoms is not known. This case highlighted management issues using combination short-acting octreotide infusion with long-acting lanreotide during carcinoid crisis. The patient had left lung neuroendocrine tumour that metastasized to his liver and bone, post left lobectomy. Due to extensive metastasis to the liver causing recurrent carcinoid crisis, he required shorter interval long-acting lanreotide with continuous infusion of short-acting octreotide, which led to transient diabetes insipidus. Symptoms resolved with discontinuation of treatment. Somatostatin analogues, especially in combination, may inhibit the posterior pituitary resulting in diabetes insipidus. Prompt withdrawal of short-acting somatostatin analogue and initiation of desmopressin can reverse the complication. It is important to recognize this complication with combination of octreotide and lanreotide injections to avoid serious complications.
Diabetes Insipidus ; Octreotide ; Neuroendocrine Tumors ; Malignant Carcinoid Syndrome

Neuroendocrine neoplasms of larynx are a rare group of tumors that include typical carcinoid, atypical carcinoid, small cell neuroendocrine carcinoma and paraganglioma. Among them, typical carcinoid is the least common type and the treatment and prognosis is different from the other tumors. We report a case of recurrent typical carcioid of supraglottis with interval of 5 years, which were excised locally at each time. As far as we know, this is the 15th case of a typical carcinoid of larynx.
Carcinoid Tumor* ; Carcinoma, Neuroendocrine ; Larynx ; Neuroendocrine Tumors ; Paraganglioma ; Prognosis

Primary meningioma of jugular foramen is extremely rare, while paraganglioma or nerve sheath tumor are relatively common in jugular foramen. We reported a case of primary meningioma of jugular foramen. A 79-year-old female who had left tinnitus and hearing loss for three month came to the department of otorhinolaryngology. Temporal bone computed tomography scan showed sclerotic change and slightly irregular margins of left jugular foramen with relatively preservation of bony architecture. Temporal bone magnetic resonance image showed well defined homogeneous enhancing mass in left jugular foramen with extension to carotid space on gadolinium enhanced T1 weighted image. Prominent dural tail was also noted. On T2 weighted image, this mass showed intermediated signal intensity with no vascular signal voids. Meningioma was confirmed by pathology. In this article, we describe a case of primary en plaque meningioma of jugular foramen and review image findings of differential diagnosis.
Aged ; Diagnosis, Differential* ; Female ; Gadolinium ; Glomus Jugulare Tumor ; Hearing Loss ; Humans ; Meningioma* ; Neurilemmoma ; Otolaryngology ; Paraganglioma ; Pathology ; Tail ; Temporal Bone ; Tinnitus

Paragangliomas are neoplasms that arise from extra-adrenal paraganglia, microscopic islands of cells derived from the neural crest. In the head and neck region, paraganglionic tissue is distributed in the superior and inferior paraganglia, the carotid body, the vagal body, and the jugulotympanic region. Approximately 10% of patients with a paraganglioma have a family history of such tumors. Multiple lesions can be found in 26% of patients with family history. Patients with multiple paragangliomas have a higher risk of having functional pheochromocytoma and should undergo a pretreatment screening for vasopressor substances. Similarly, patients with a family history should undergo four-vessel arteriography to rule out any multiple and clinically unrecognized lesions. The authors have experienced three cases of multiple paragangliomas, which were managed surgically. Two cases were bilateral carotid body tumors and two cases were accompanied by glomus jugulare. Of these, one case had family history. We report three cases of multiple paragangliomas with a review of literatures.
Angiography ; Aortic Bodies ; Carotid Body ; Carotid Body Tumor ; Glomus Jugulare ; Head ; Humans ; Islands ; Mass Screening ; Neck ; Neural Crest ; Paraganglioma* ; Pheochromocytoma

BACKGROUND/AIMS: Endoscopic resection is the first-line treatment for rectal neuroendocrine tumors (NETs) measuring < 1 cm and those between 1 and 2 cm in size. However, conventional endoscopic resection cannot achieve complete resection in all cases. We aimed to analyze clinical outcomes of precut endoscopic mucosal resection (EMR-P) used for the management of rectal NET. METHODS: EMR-P was used to treat rectal NET in 72 patients at a single tertiary center between 2011 and 2015. Both, circumferential precutting and EMR were performed with the same snare device in all patients. Demographics, procedural details, and histopathological features were reviewed for all cases. RESULTS: Mean size of the tumor measured endoscopically was 6.8±2.8 mm. En bloc and complete resection was achieved in 71 (98.6%) and 67 patients (93.1%), respectively. The mean time required for resection was 9.0±5.6 min. Immediate and delayed bleeding developed in six (8.3%) and 4 patients (5.6%), respectively. Immediate bleeding observed during EMR-P was associated with the risk of delayed bleeding. CONCLUSIONS: Both, the en bloc and complete resection rates of EMR-P in the treatment of rectal NETs using the same snare for precutting and EMR were noted to be high. The procedure was short and safe. EMR-P may be a good treatment choice for the management of rectal NETs.
Carcinoid Tumor ; Demography ; Hemorrhage ; Humans ; Neuroendocrine Tumors* ; Rectum ; SNARE Proteins