No abstract available.
Neural Tube Defects*

No abstract available.
Neural Tube Defects* ; Neural Tube* ; Prenatal Diagnosis*

We report the case of a 33-week-old female fetus born with craniorachischisis to a gravida 5, para 4 (3104) mother with no previous history of conceiving a child with a neural tube defect. Craniorachischisis is characterized by anencephaly and an open defect extending from the brain to the spine and is the most severe and fatal type of neural tube defect. Although the cause of neural tube defects is hypothesized to be multifactorial and is usually sporadic, the risk is increased in neonates born to mothers with a family history or a previous pregnancy with neural tube defect, both of which are not present in the index case. This case is unique in that only during the fifth pregnancy did the couple conceive a child with a neural tube defect, emphasizing that folic acid supplementation, the sole preventive measure proven to decrease the risk of neural tube defects, remains to be important in the periconceptual period for all women of childbearing age.
Autopsy ; Congenital Abnormalities ; Neural Tube Defects ; Neural Tube Defects

No abstract available.
Neural Tube Defects* ; Spinal Canal*

A sex determination method has been developed using the polymerase chain reaction (PCR) which involved the amplification of sex determining region Y (SRY) gene and the amplification of the HLA-DQ gene as an internal control, in the one PCR reaction using two sex of the primers. The PCR products were sort ADN of 139 bp for SRY and 239/242 bp for HLA-DQ region spectively. The amplification of this method in prenatal diagnosis to prevent genetic diseases, in forensic science.
Fetus ; Neural Tube Defects ; Aneuploidy

In this study, serum samples collected from 48 high-risk pregnant women were screened for three markers: alpha-feto protein (AFP), beta-human chorionic gonadotropin (b-HCG) and conjugated estriol (UE3) to define the risk of congenital aneuploidy and neural tube defect...The result showed the serum AFP level raised in two cases (more than 2.5MoM - Multiple of Median). One case has decrease in AFP (less than 0.06MoM) combined with decrease in UE3. Once has decrease in AFP (less than 0.06mOM) combined with increase in b-HCG. One case has decrease in AFP (less than 0.06MoM) combined with decrease in UE3 and increase in b-HCG level. One case has decrease in AFP alone (less than 0.06MoM). Fetal neural tube defect was identified in one case. Other four cases have increase in b-HCG only. these pregnancies should be referred to genetic study and further tests.
Fetus ; Neural Tube Defects ; Aneuploidy

No abstract available.
Child ; Humans ; Neural Tube Defects

A case of neurenteric cyst within the cervical canal is reported. He has been suffered from gradual aggravated quardriparesis since 4 months. On spine C-T scan and cervical myelographic examination, intradural extramedullary mass was detected. And so total laminectomy of C4, C5 and C6 was performed. We could diagnose by the pathological findings.
Laminectomy ; Neural Tube Defects* ; Spinal Canal* ; Spine

Myelodysplasia syndrome is a diseases group of which quite difficult cure and prediction. There are many treatment methods however it depends on patient’s age, level of diease, rate of blast in bone marrow. The treatment includes: chemical treatment, trasplant originative cell, support treatment. Other method is combination of various treatment methods: Use Ara-C combine with depersolon, chemical treatment combine with stimulative agent of blood and trasplant originative cell
Neural Tube Defects ; Bone Marrow ; Cytarabine ; Therapeutics

OBJECTIVE: The objective of this study is to determine whether the club foot of the affected fetus is related to the location, size, and rupture state of the spinal neural tube defect lesion. METHODS: Ultrasound and medical records of 21 fetuses with spinal neural tube defect were reviewed. At the time of diagnosis 7 fetuses had clubfoot and 14 fetuses didn't have. All the fetuses with spinal neural tube defect were divided into two groups, one with clubfoot fetuses, and the others without clubfoot. RESULTS: The mean lesion size of the clubfoot group was significantly larger than normal foot group (4.1+/-1.22 cm vs 2.1+/-1.59 cm). And the level of lesion is significantly higher in club foot group. But the rate of sac rupture is lower in club foot group. CONCLUSION: The fetuses with clubfoot detected at the time of diagnosis had larger size and higher level of lesion.
Clubfoot ; Diagnosis ; Fetus* ; Foot* ; Medical Records ; Neural Tube Defects* ; Neural Tube* ; Rupture ; Ultrasonography ; Ultrasonography, Prenatal*