No abstract available.
DNA* ; Kinetics* ; Nervous System Neoplasms* ; Nervous System*

Tumors of central nervous system are common, especially in children. The most common primary tumor is astrocytoma. Study of microscopic features of astrocytoma could help to diagnose and assess histologically this type of tumor more precisely. Subjects include 122 patients with astrocytoma diagnosed at Department of Pathology, Cho Ray Hospital from June 2003 to June 2004. Histological criteria of these 122 cases were atypical nuclear: 122 cases (100%), endothelial proliferation: 69 (56.5%), necrosis: 36 (29.5%), mitoses: 17 (13.9%), micro cystic: 17 (13.9%), calcification: 6 (4.9%), pseudorosettes: 8 (6.5%). The criteria such as atypical nuclear, endothelial proliferation, necrosis, mitoses, and cellularity are important factors in the diagnosis and histological grading of astrocytoma
Astrocytoma ; Central Nervous System Neoplasms ; Diagnosis ; Child

There has been a marked increase in the utility of aspiration cytology for pathologic diagnosis. It may be applied to any kinds of organs and substitutes surgical biopsy. Because of the high risk of complication and difficulties in localization, aspiration cytology in the central nervous system(CNS) has been used with less frequency compared to other sites. However, with the advent of sophisticated imaging instruments, aspiration cytology of lesions in the CNS is being used increasingly. Cytologic features of the CNS neoplasms were quite similar to those of histology except one spindle cell tumor. Reviewing various CNS neoplasms, it appears that cytology may be a useful diagnostic method.
Biopsy ; Brain Neoplasms ; Central Nervous System* ; Diagnosis

No abstract available.
Central Nervous System Neoplasms ; Cerebral Ventricle Neoplasms ; Lymphoma*

Carcinoembryonic antigen(CEA) in blood and CSF was reported to be increased in cases of nervous system neoplasms by some investigators. To evaluate the oncological diagnostic value of CEA in the neurosurgical conditions, this study has been performed on 24 nervous system neoplasms and 8 non-nervous system as well as 49 controls. In addition, alpha-fetoprotein was also measured on the same conditions because of its close oncologic nature and recent diagnostic application on the general surgical conditions. The CEA concentration in blood and CSF were determined by CEA Radioimmunoassay kit, and the alpha-fetoprotein in blood and CSF were determined by GammaDab kit. The result showed that concentration of CEA and alpha-fetoprotein was higher and seemed to diagnostic in Extra-CNS neoplasma. In nerovous system, however, these were the lower than we expected, although were higher than control. Moreever, these levels were not unique on same oncologic condition and rather somewhat variable. From these results, increased concentration of these itself may be considered suggestive of existence of nervous system neoplasm, but it does mean neither degree of malignancy nor its origin.
alpha-Fetoproteins* ; Carcinoembryonic Antigen* ; Central Nervous System ; Humans ; Nervous System Neoplasms ; Radioimmunoassay ; Research Personnel

Neurilemmomatosis is a clinical entity consisting of multiple cutaneous neurilemmomas, central nervous system tumors, and neurologic disorders. Since Shishiba et al first described the disorder in 1984, several cases have been reported. We report a Korean case of neurilemmomatosis showing multiple neurilemmomas of the skin and spinal cord, with associated motor and sonsory nerve disturbance. Histologic, immunohistopathologic and electron microscopic studies confirmed the diagnosis.
Central Nervous System Neoplasms ; Diagnosis ; Nervous System Diseases ; Neurilemmoma ; Skin ; Spinal Cord

Acupuncture Therapy ; Aged ; Female ; Humans ; Nervous System Neoplasms ; therapy ; Paraneoplastic Syndromes, Nervous System ; therapy

Radiation therapy is highly effective for the management of pediatric malignant central nervous system (CNS) tumors including embryonal tumors. With the increment of long-term survivors from malignant CNS tumors, the radiation-related toxicities have become a major concern and we need to improve the treatment strategies to reduce the late complications without compromising the treatment outcomes. One of such strategies is to reduce the radiation dose to craniospinal axis or radiation volume and to avoid or defer radiation therapy until after the age of three. Another strategy is using particle beam therapy such as proton beams instead of photon beams. Proton beams have distinct physiologic advantages over photon beams and greater precision in radiation delivery to the tumor while preserving the surrounding healthy tissues. In this review, I provide the treatment principles of pediatric CNS embryonal tumors and the strategic improvements of radiation therapy to reduce treatment-related late toxicities, and finally introduce the increasing availability of proton beam therapy for pediatric CNS embryonal tumors compared with photon beam therapy.
Brain ; Central Nervous System Neoplasms ; Central Nervous System ; Child ; Humans ; Proton Therapy ; Protons ; Survivors

Autonomic Pathways ; Humans ; Parasympathetic Nervous System ; Stomach Neoplasms ; Sympathetic Nervous System

CEREBELLOPONTINE ANGLE CEREBELLUM METENCEPHALON RHOMBENCEPHALON BRAIN STEM BRAIN CENTRAL NERVOUS SYSTEM NERVOUS SYSTEM NEOPLASMS