No abstract available.
Nerve Fibers* ; Retinaldehyde*

No abstract available.
Gallbladder ; Nerve Fibers

A glomus tumor is a benign neoplasm of neuromyo-arterial glomus, composed of vascular channels surrounded by proliferating glomus cells and nerve fibers. Occasionally it displays unusual histopathologic features such as a large size, deep location, infiltrative growth, mitotic activity, nuclear pleomorphism, or necrosis. It can be diagnosed as an "atypical" glomus tumor, including malignant glomus tumor, glomus tumor of uncertain malignant potential, symplastic glomus tumor, or glomangiomatosis. Glomangiomatosis and symplastic glomus tumors reveal benign biologic behavior. We report a typical case of a symplastic glomus tumor, showing only marked nuclear atypia, compared with a classical glomus tumor.
Glomus Tumor* ; Necrosis ; Nerve Fibers

Neurofibromas are benign tumors composed of a complex proliferation of neuromesenchymal tissue with residual nerve fibers. There are several distinct types of neurofibromas: cutaneous, subcutaneous, nodular plexiform, and diffuse plexiform. To our knowledge, none of these have previously been described in association with alopecia in the literature. We present a case of neurofibroma of the scalp which is associated with alopecia.
Alopecia* ; Nerve Fibers ; Neurofibroma* ; Scalp

The author measured the severity of brain damage of 36 rabbits irradiated 2.45 GHz microwave for 10 minutes, 20 minutes and 30 minutes, respectively. Electromicroscopic and light microscopic findings of just after, 1 weeks, 2 weeks and 4 weeks after irradiated brain were compared in each time. Swelling and vacualization of nerve cell and mitochondria were noted. Also these changes tend to increased severity along amount of radiation, but revealed reversible changes with time. Myelinated and unmyelinated nerve fibers were examined as same manner. These nerve fibers also revealed swelling and vascuolization, these findings also tend to increase severity with irradiation power and more prominent at unmyelinated nerve fibers. Reversability of these findings after each time period were more prominent in myelinated nerve fibers than unmyelinated nerve fibers.
Brain ; Cerebrum* ; Microwaves* ; Mitochondria ; Myelin Sheath ; Nerve Fibers ; Nerve Fibers, Myelinated ; Nerve Fibers, Unmyelinated ; Neurons ; Rabbits*

PURPOSE: To evaluate the efficiency of digital retinal nerve fiber layer (RNFL) photographs converted from a non-mydriatic digital fundus camera for detecting RNFL defects. METHODS: Ninety-five eyes were evaluated with both a non-mydriatic digital fundus photograph and a digital RNFL photograph by two glaucoma specialists independently. The red-free, monochrome modified digital fundus photograph was acquired from non-mydriatic digital fundus photographs using Photoshop 7.0. Whether a localized wedge-shaped or diffuse RNFL defect existed or not was evaluated on a non-mydriatic digital fundus photograph and a modified digital fundus photograph, and inter- and intraobserver agreement were also evaluated. Regarding the use of digital RNFL photographs as a standard method, we calculated the sensitivity, specificity, and positive and negative predictive values of the two types of photographs. RESULTS Interobserver agreement (Cohen's kappa values) about localized RNFL defects observable on digital RNFL photographs, non-mydriatic digital fundus photographs, and modified digital fundus photographs were 0.749, 0.634, and 0.793, respectively, but all were 0.417 or less with regard to diffuse RNFL defects. Regarding localized RNFL defects, the sensitivity, specificity, and positive and negative predictive values of modified digital fundus photographs were 85.7%, 95.5%, 85.7% and 94.1%, respectively, showing superiority to those of non-mydriatic digital fundus photographs. But, in cases of diffuse RNFL defect, the sensitivity and specificity of modified digital fundus photographs were 60.0% and 97.8%, respectively, indicating no superiority to non-mydriatic digital fundus photographs. CONCLUSIONS: The localized RNFL defect can be detected more efficiently with modified digital fundus photographs than non-mydriatic digital fundus photographs, but the diffuse RNFL defect cannot.
Glaucoma ; Nerve Fibers ; Retinaldehyde* ; Sensitivity and Specificity ; Specialization

PURPOSE: To evaluate the efficiency of digital retinal nerve fiber layer (RNFL) photographs converted from a non-mydriatic digital fundus camera for detecting RNFL defects. METHODS: Ninety-five eyes were evaluated with both a non-mydriatic digital fundus photograph and a digital RNFL photograph by two glaucoma specialists independently. The red-free, monochrome modified digital fundus photograph was acquired from non-mydriatic digital fundus photographs using Photoshop 7.0. Whether a localized wedge-shaped or diffuse RNFL defect existed or not was evaluated on a non-mydriatic digital fundus photograph and a modified digital fundus photograph, and inter- and intraobserver agreement were also evaluated. Regarding the use of digital RNFL photographs as a standard method, we calculated the sensitivity, specificity, and positive and negative predictive values of the two types of photographs. RESULTS Interobserver agreement (Cohen's kappa values) about localized RNFL defects observable on digital RNFL photographs, non-mydriatic digital fundus photographs, and modified digital fundus photographs were 0.749, 0.634, and 0.793, respectively, but all were 0.417 or less with regard to diffuse RNFL defects. Regarding localized RNFL defects, the sensitivity, specificity, and positive and negative predictive values of modified digital fundus photographs were 85.7%, 95.5%, 85.7% and 94.1%, respectively, showing superiority to those of non-mydriatic digital fundus photographs. But, in cases of diffuse RNFL defect, the sensitivity and specificity of modified digital fundus photographs were 60.0% and 97.8%, respectively, indicating no superiority to non-mydriatic digital fundus photographs. CONCLUSIONS: The localized RNFL defect can be detected more efficiently with modified digital fundus photographs than non-mydriatic digital fundus photographs, but the diffuse RNFL defect cannot.
Glaucoma ; Nerve Fibers ; Retinaldehyde* ; Sensitivity and Specificity ; Specialization

The Nerve Fiber Layer Anlyzer (LDT Inc., U.S.A.) is a scanning laser polarimetric ophthalmoscopy that uses the polarizing properties of the retinal nerve fiber layer. I performed 10 consecutive measurements from 15degrees peripapillary area in 10 normal eyes and 10 glaucomatous eyes to evaluate the reproducibility of the instrument. The nerve fiber layer thickness was are 76.8+/-9.0m for normal subjects and 81.5+/-8.4m for galucoma patients. The mean coeffitient of variation of the 1.5 disc diameters (15degrees) for normal subjects was 11.6(3.14-11.27) and for glaucoma eyes was 10.4(2.4612.46). This results indicate that the reproducibility of NFA was good in measuring the retinal nerve fiber layer thickness. Further investigation seems warranted to compare normal and glaucomatous eyes.
Glaucoma ; Humans ; Nerve Fibers* ; Ophthalmoscopy ; Retinaldehyde*

No abstract available.
Glaucoma* ; Humans ; Nerve Fibers* ; Photography* ; Retinaldehyde*

PURPOSE: To compare retinal nerve fiber layer (RNFL) thickness obtained with Stratus optical coherence tomography (OCT) and Cirrus OCT. METHODS: Sixty-one normal eyes were evaluated with Stratus and Cirrus OCT on the same day, and the RNFL thicknesses measured by the two OCT machines were compared. The correlation between the two data sets was obtained using Pearson's correlation coefficient. The correlation between RNFL thickness and the difference in data measured by the two OCT machines was then assessed. RESULTS: The average RNFL thickness was significantly higher with Stratus OCT by 6.54+/-4.48 micrometer (p=0.0008). A strong correlation was present between the two RNFL thickness data sets (r=0.883), and the difference between Stratus and Cirrus values tended to increase as RNFL thickness increased. CONCLUSIONS: RNFL thickness measurements in normal eyes scanned with Cirrus OCT correlate well with Stratus OCT measurements. Average RNFL thickness was significantly higher with Stratus OCT, and as the RNFL thickness increased, the difference between Stratus and Cirrus values increased.
Eye ; Nerve Fibers ; Retinaldehyde ; Tomography, Optical Coherence