Congenital mesoblastic nephroma is a slow-growing tumor considered to originate from renal mesenchyme and usually discovered before the age of 6 months. The tumor is almost invariably benign but has been mistaken for Wilms` tumor and unnecessarily overtreated. We report a case of congenital mesoblastic nephroma in 2 months aged infant.
Humans ; Infant ; Mesoderm ; Nephroma, Mesoblastic*

Congenital mesoblastic nephroma is relatively rare congenital disease. It occurs in the early neonatal period as an unencapsulted and locally invasive fibrous lesion. Survival following nephrectomy alone is excellent but local recurrence and metastases have been reported. Herein we present one case of congenital mesoblastic nephroma. A 13-day-old male infant admitted our hospital with chief complaint of palpable left abdominal mass. After nephrectomy, histologic diagnosis is congenital mesoblastic nephroma.
Diagnosis ; Humans ; Infant ; Male ; Neoplasm Metastasis ; Nephrectomy ; Nephroma, Mesoblastic* ; Recurrence

No abstract available.
Humans ; Infant, Newborn ; Infant, Premature* ; Nephroma, Mesoblastic* ; Ultrasonography, Prenatal*

The mesoblastic nephroma is a rare benign renal tumor that frequently appears as a neonatal abdominal mass. This benign tumor is composed primarily of connective tissue that growth between intact nephrons and often replaces most of the renal parenchyme. Contrast media within the calyceal systems are seen within the tumor representing function by nephrons trapped within the mass. Prognosis after complete excision is excellent.
Connective Tissue ; Contrast Media ; Nephroma, Mesoblastic* ; Nephrons ; Prognosis

Mesoblastic nephroma or fetal mesenchymal hamartoma of the kidney is an uncommon congenital tumor of infancy that rarely occurs in adults. This tumor is slow growing tumor considered to originate from renal mesenchyme and is separated this relatively benign lesion from its malignant counterpart, malignant nephroblastoma(Wilms` tumor). We report a case of mesoblastic nephroma incidentally detected left renal mass and treated with radical nephrectomy in 50 years old man.
Adult* ; Hamartoma ; Humans ; Kidney* ; Mesoderm ; Middle Aged ; Nephrectomy ; Nephroma, Mesoblastic*

Mesoblastic nephroma is an important differential diagnosis of a renal mass occurring in the neonatal period or in early childhood. It is a rare monomorphous congenital renal neoplasm most commonly recognized during the first 3 months of life. With the widespread application of ultrasound imaging, many cases are recognized prior to birth. We report a case of mesoblastic nephroma detected by ultrasonograph at 36 weeks of intrauterine fetal life and removed after birth. It showed a well circumscribed, grayish white, solid mass measuring 4x3x2 cm. The tumor was predominantly a classic type with a focal cellular pattern. Immunohistochemical and electron microscopic studies were done.
Diagnosis, Differential ; Kidney ; Kidney Neoplasms ; Nephroma, Mesoblastic* ; Parturition ; Ultrasonography

Mesoblastic nephroma is an uncommon renal tumor reported in infants but rarely in adults. We describe a case of calcified mesoblastic nephroma occurring in an adult. It is difficult, on the basis of radiologic images, to differentiate between calcified mesoblastic nephroma and calcified renal cell carcinoma.
Adult* ; Carcinoma, Renal Cell ; Humans ; Infant ; Nephroma, Mesoblastic*

A multilocular cyst of kidney is a rare pathological entity, which has been reported in the literature under several names. These various names reflect the controversy surrounding their nature. This tumor is traditionally regarded as benign in nature and a nephrectomy has to be performed because of the difficulty in its accurate diagnosis. Malignant recurrence of a multilocular cyst of kidney has an even rarer incidence, with only a few cases having been reported. We report a case of 50-year-old male, with an incidentally detected right renal cystic mass. This mass was pathologically confirmed as a multilocular cyst of kidney after a radical nephrectomy, which locally recurred as a malignant mesoblastic nephroma.
Diagnosis ; Humans ; Incidence ; Kidney Diseases, Cystic ; Kidney* ; Male ; Middle Aged ; Nephrectomy ; Nephroma, Mesoblastic ; Recurrence*

The descriptive term "mixed epithelial and stromal tumor of the kidney" was recently proposed for a group of renal tumors characterized histologically by a mixture of stromal and epithelial proliferation. It is a rare benign neoplasm of the kidney which has been reported under various names such as adult type mesoblastic nephroma or others. We report a case of mixed epithelial and stromal tumor in a 47 yr old female patient presenting as a partly cystic and partly solid renal mass. Microscopically, the tumor exhibited spindle cell component in solid portion and epithelial proliferation around microcystic areas. Immunoreactive profiles and ultrastructural examination suggested myofibroblastic nature of the stromal cells. We believe this case exemplifies a unique adult renal tumor displaying both epithelial and stromal neoplastic component and has a few unusual features worthy of attention.
Nephroma, Mesoblastic/pathology ; Neoplasms, Glandular and Epithelial/*pathology ; Middle Aged ; Kidney Neoplasms/*pathology ; Humans ; Female ; Diagnosis, Differential

Congenital mesoblastic nephroma (CMN) is generally considered to be a rare benign renal tumor in neonates, requiring only total excision. However, an atypical mesoblastic nephroma (AMN) may behave aggressively, in contrast to a congenital mesoblastic nephroma. AMN shows atypical gross and microscopic features such as hemorrhage, necrosis, high cellularity, and a mitotic index. We report a case of atypical mesoblastic nephroma which presented in a 2 month-old male infant. Grossly, the tumor involved the upper and the midportion of the left kidney. On section, the cut surface was flesh,which was hemorrhagic necrotic, multicystic degenerative, grayish-white, and heterogenous. Microscopically, the tumor showed a high degree of cellularity and an arrangement of monophagic ovoid spindle cells in sheets and vague interlacing bundles. The individual tumor cells showed fusiform to oval nuclei, indistinct scanty pale-eosinophilic cytoplasm, and many mitotic features.
Cytoplasm ; Hemorrhage ; Humans ; Infant ; Infant, Newborn ; Kidney ; Male ; Mitotic Index ; Necrosis ; Nephroma, Mesoblastic*