Humans ; Hypopharyngeal Neoplasms ; therapy ; Laryngeal Neoplasms ; therapy

Background: Gastric cancer is the second common disease among types of cancer, followed by lung cancer for male and breast cancer for female. The selection of appropriate regimens for illness and economic conditions of patients is always a difficult problem for clinicians. Objectives: To assess preliminary results of chemotherapy in treatment of gastric cancer in Hai Phong. Subjects and method: A longitudinal, cross-section study was conducted on 57 patients with gastric cancer (35 male, 21 female), treated in Viet Tiep hospital from January, 2002 to June, 2006. All of them were in stage of Dukes C, treated postoperative supported chemotherapy. Results: Side effects were common seen as vomit, nausea and diarrhea. They were often mild and disappeared after stopping medication. 30/57 patients responded to treatment. 21 patients were treated with regimen 5FU, however, amount of treatment cycles was very scattered and treatment effect was unclear. 36 patients were treated with multi-chemical regimens as FUFA, FAM and ELF. Their response to treatment was more clearly than regimen 5FU. During treatment, there were 6 patients who had not completely responded to treatment. In which, 4 patients developed more seriously: metastasis to liver, ovary, bone and lung. 2 patients had died. Conclusion: Regimen 5FU had a little toxicity. Regimen FUFA was more effective. The role of chemotherapy in supported treatment was unclear. Chemotherapy could be applied to patients with early stage of Dukes B.
Stomach Neoplasms/ therapy ; Drug Therapy ;

Genetic Therapy ; Mouth Neoplasms ; therapy

No abstract available.
Colorectal Neoplasms* ; Drug Therapy*

No abstract available.
Drug Therapy* ; Stomach Neoplasms*

No abstract available.
Drug Therapy* ; Stomach Neoplasms*

No abstract available.
Drug Therapy* ; Stomach Neoplasms*

No abstract available.
Drug Therapy* ; Stomach Neoplasms*

Background: Surgical treatment of esophageal carcinoma is a main operation in term of both technique and anesthesiology. The Orringer technique is one of the treatments. Objectives: 1. To describe clinical and subclinical characteristics of the middle and lower-third esophageal carcinoma. 2. To assess preliminary results of Orringer technique in treating of the middle and lower-third esophageal carcinoma. Subjects and method: A prospective, descriptive, following by time study was conducted in the patients who were diagnosed the middle and lower third esophageal carcinoma and operated by Orringer technique at the Department of Digestive Surgery in Viet Duc Hospital from January/2000 to June/2006. Results: The subclinical symptoms included difficult swallow (98.5%), anorexia and loss weight (98.5%), pain in chest (23.5%), loss of voice (2.9%) and bloody vomiting (5.9%). For clinical symptoms, 54/68 patients (79.4%) had lesions in lower-third esophageal, 14/68 (20.6%) had lesions in the middle-third esophageal. The average length of the lesions was 6.23\xb12.22cm (95% CI=5.69-6.77). The average operation time was 273.38 \xb154.56 minutes (range: 140-420), which is much faster than those in esophagectomy via thoracotomy: Lewis-Santy technique (324 minutes) and Akiyama technique (480 minutes). Both intraoperative and post-operative complications of Orringer technique were less than those of esophagectomy via thoracotomy. Conclusion: In this study, the clinical and subclinical strongest characteristics of the patients with the middle-third esophageal carcinoma appear in the advanced period (III period and IV period (over 70%)). Orringer technique had faster operation time, less complications and lower mortality than those of esophagectomy via thoracotomy.
Esophageal Neoplasms/ surgery ; therapy

The minimal condition for chemotherapy is the malignant nature of tumor must be identified exactly, the clinical criteria must be established adequately and accurately, contraindications should be excluded, the following-up factors were enough and the cooperation of patients should be available. In this clinical trial, patients were divided randomly into 3 groups. Group 1 received surgery alone. Group 2 received surgery plus 5FU. Groups 3 received surgery plus 5FU and false ginseng. Result: The 5-year survival rate increased more than 15% for groups received post-operative adjunctive therapy. The 5-year survival in adjunctive therapy groups is 45%.
Immunotherapy ; Drug Therapy ; neoplasms