No abstract available.
Neoplasms, Glandular and Epithelial*

No abstract available.
Humans ; Neoplasms, Glandular and Epithelial ; Ovarian Neoplasms

The standard treatment of advanced ovarian cancer is rapidly changing. As we begin to understand that epithelial ovarian cancer is a heterogeneous disease, our treatment strategies are evolving to include novel biologic drugs that specifically exploit altered pathways. Surgery remains an essential component in the treatment of ovarian cancer; however, the importance of surgical specialization and defining "optimal cytoreduction" as no visible residual disease has been further validated. Ongoing studies are defining the role of neoadjuvant chemotherapy in the upfront treatment of advanced ovarian cancer. In addition, clinical trials are evaluating intraperitoneal, dose dense, antiangiogenic drugs as well as targeted maintenance therapies which will establish new standards of care in the near future.
Neoplasms, Glandular and Epithelial ; Ovarian Neoplasms ; Standard of Care

No abstract available.
Biomarkers ; Neoplasms, Glandular and Epithelial ; Ovarian Neoplasms

A study on 537 cases of gastrotrectomy due to the cancer in Viet Duc hospital during 1993-1997 has shown that the gastric cancer that did not belong to the glandular epithelioma accounted for 23 cases (4.3%) of which malignant lymphoma (12/23), malignant peripheral neuroma (7/2) and smooth muscelar tumor (3/23). Most of them hospitalized due to the abdominal pain, 1 cases of gastric perforation and 2 cases of digestive haemorrhage, 12 cases found the abdominal tumor 7 cases had lesion in the cardiapyloric region. The treatment involved the half total gastrectomy and tumor disection, 2 cases received the left hepatic lobe disection, 3 cases of splenectomy. There were no cases treated by the combination of chemotherapy and radiation.
Stomach Neoplasms ; Neoplasms, Glandular and Epithelial ; diagnosis ; therapeutics

PURPOSE: Computed tomographic(CT), ultrasonographic(US) findings of solid and papillary epithelial neoplasm of the pancreas were correlated with pathologic findings for the better understanding of this disease entity. METHODS AND MATERIALS: A retrospective review of CT and US of 14 cases of solid and papillary epithelial neoplasm of the pancreas was carried out in terms of the margin, internal architecture, caicification and septation, and this was correlated with gross pathologic findings. RESULTS: CT and US findings were well defined round masses consisting of both solid and cystic components. Five cases were cystic, four cases were solid and five cases were mixed. Cystic portion of the tumor represented variable degree of hemorrhagic necrosis. Six cases contained foci of calcification, which were linear, marginal and amorphous. Marginal calcification interfered US examination of the mass in three cases. Internal septurn was demonstrated in four cases on CT, one case on US and three cases on gross specimen. CONCLUSIONS: Our results indicate that calcification and internal septurn were considered as a part of radiologic findings in solid and papillary epithelial neoplasm of the pancreas.
Necrosis ; Neoplasms, Glandular and Epithelial* ; Pancreas* ; Retrospective Studies

Cutaneous lymphadenoma is a benign epithelial neoplasm with lymphoepithelial infiltration that is supposed to be from a pilosebaceous origin. We report a 44-year-old man with a nodule on the pre-auricular area showing basaloid proliferation, intraepithelial lymphocytes and immature pilosebaceous structures. The findings of our case make it possible to diagnose a cutaneous lymphadenoma with follicular differentiation and supports this occurs as a variant form of nodular trichoblastoma with adamantinoid features.
Adult ; Humans ; Lymphocytes ; Neoplasms, Glandular and Epithelial

Humans ; Neoplasms, Glandular and Epithelial ; Thymoma ; Thymus Neoplasms ; Thyroid Neoplasms

BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) is not commonly used in the colorectal area because of technical difficulty and due to the characteristics of the organ. We therefore wanted to determine the efficacy and safety of endoscopic submucosal dissection in colorectal neoplasms. METHODS: Colorectal tumor lesions resected by ESD in a single medical center were analyzed retrospectively. RESULTS: A total of 47 patients were treated for 50 lesions. Mean age was 64.3+/-9.8 (43~85) years. Laterally spreading tumors were the most common type (44, 88%) followed by Is+IIa type tumors (6, 12%). The en bloc resection rate was 76% and the complete resection rate was 74%. The mean procedure time was 81.1+/-44.7 (20~180) minutes. The mean size of resected specimen was 26.9+/-10.4 (10~50) mm. The histological diagnosis determined that 24 lesions (48%) were tubular adenoma, 18 lesions (36%) were intramucosal cancer, 7 lesions (14%) were sm1 cancer and 1 lesion (2%) was over sm2 cancer. Bleeding occurred in 6 (12%) and perforations in 13 (26%) of the patients and all were treated successfully by endoscopic or conservative treatment. The concordance rate of pre and post ESD pathological diagnosis was only 47%. CONCLUSIONS: ESD is a feasible technique for treating superficial colorectal tumors with a high complete resection rate, minor invasiveness, and a high safety rate. In addition, ESD might be useful in establishing the complete pathological evaluation of colorectal epithelial neoplasm.
Adenoma ; Colorectal Neoplasms ; Hemorrhage ; Humans ; Neoplasms, Glandular and Epithelial ; Retrospective Studies

PURPOSE: CD24 is a small heavily glycosylated glycosylphosphatidylinositol-linked cell surface protein, which is expressed in hematological malignancies as well as a large variety of solid tumors. The authors aimed to evaluate the CD24 protein expression in fibroadenomas and adenocarcinomas of the breast and its correlation to clinicopathological data. METHODS: Immunohistochemical staining for CD24 was performed on 28 mammary neoplasia, diagnosed as either adenocarcinomas (22 cases) or fibroadenomas (6 cases), to examine the relationship with clinicopathological parameters. The results of the immunohistochemical staining were evaluated by the stainability (negative, weak-, moderate-, strong-positive) and staining patterns (membranous vs. intracytoplasmic) for statistical analyses. RESULTS: The present study clearly demonstrates that CD24 was abundantly expressed in adenocarcinoma, compared to in fibroadenomas of the breast (P<0.001). Intracytoplasmic staining was noted in the adenocarcinomas only but this was not statistically significant between the adenocarcinoma and fibroadenoma groups. No significant correlations of the CD24 stainability or staining pattern were detected with the nodal status, tumor histological grade or histological subtypes. CONCLUSION: Our data suggest that abundant membranous expression or intracytoplasmic expression of CD24, as detected by immunohistochemistry, is an important tissue marker for a mammary epithelial neoplasm, which could help to define adenocarcinomas from fibroadenomas.
Adenocarcinoma ; Breast ; Fibroadenoma ; Hematologic Neoplasms ; Immunohistochemistry ; Neoplasms, Glandular and Epithelial