1.Spontaneous Regression of Hyperplastic Gastric Polyps.
Soo Yong CHOI ; Jong Kyu PARK ; Sang Jin LEE ; Woo Jin JUNG ; Hak Soo KIM ; Gab Jin CHEON ; Dae Woon EOM
The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2017;17(4):213-217
Although gastric hyperplastic polyps are recognized as benign lesions, there is concern regarding carcinomatous changes in the polyps, depending on their size. If the polyp size is larger than 1.0~2.0 cm, endoscopic resection is usually recommended. Gastric hyperplastic polyps easily undergo changes in their shape and size over time. However, spontaneous regression of hyperplastic polyps is very rare. We present a recent case wherein gastric hyperplastic polyps disappeared spontaneously. We present the case along with a literature review.
Neoplasm Regression, Spontaneous
;
Polyps*
;
Stomach
2.A Case of Gastric Langerhans Cell Histiocytosis with Spontaneous Regression.
Keum Bit HWANG ; Jun Soo HAM ; Subin HWANG ; Suk Hyeon JUNG ; Jun Haeng LEE
The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2015;15(4):270-273
A 44-year-old male was followed-up with esophagogastroduodenoscopy due to an esophageal submucosal tumor. On the lesser curvature of the gastric low body, a 0.5 cm sized round elevated lesion with hyperemia was noticed. Two pieces of biopsy were taken from this lesion for histopathologic examination. Histology showed Langerhans cell infiltration. Immunohistochemical staining was positive for CD1a antigen, which confirmed the diagnosis of Langerhans cell histiocytosis. There was no evidence of other organ involvement. The lesions spontaneously disappeared 4 months later without any treatment. We report a very rare case of gastric Langerhans cell histiocytosis.
Adult
;
Biopsy
;
Diagnosis
;
Endoscopy, Digestive System
;
Histiocytosis, Langerhans-Cell*
;
Humans
;
Hyperemia
;
Male
;
Neoplasm Regression, Spontaneous
;
Stomach
3.Spontaneous regression of tumors.
Chinese Journal of Pathology 2009;38(9):642-646
4.Spontaneous Regression of Non-Small Cell Lung Cancer in a Patient with Idiopathic Pulmonary Fibrosis: A Case Report.
Eu Dong HWANG ; Young Jae KIM ; Ah Young LEEM ; Ah Young JI ; Younjeong CHOI ; Ji Ye JUNG ; Se Kyu KIM ; Joon CHANG ; Ji Hye PARK ; Seon Cheol PARK
Tuberculosis and Respiratory Diseases 2013;75(5):214-217
Treatment of lung cancer in patients with idiopathic pulmonary fibrosis (IPF) is difficult because the mortality rate after surgery or chemotherapy is high for these patients. Spontaneous regression of cancer is rare, especially in lung cancer. A 62-year-old man, previously diagnosed with IPF, presented with stage IIIC (T2N3M0) non-small cell lung cancer. About 4 months later, spontaneous regression of the primary tumor was observed without treatment. To the best of our knowledge, this is the first report of spontaneous regression of lung cancer in a patient with IPF.
Carcinoma, Non-Small-Cell Lung*
;
Drug Therapy
;
Fibrosis
;
Humans
;
Idiopathic Pulmonary Fibrosis*
;
Lung Neoplasms
;
Middle Aged
;
Mortality
;
Neoplasm Regression, Spontaneous
5.Spontaneous Regression of Primary Renal Cell Carcinoma: A Case Report.
Seung Kang CHOI ; Soo Kee CHANG ; Jin Moo LEE ; Woo Hee JUNG ; Chan Il PARK
Yonsei Medical Journal 1986;27(4):314-318
Spontaneous regression of metastases or primary lesions of malignancy is a most intriguing phenomenon. However there were no reports of spontaneous regression of primary renal cell carcinoma. We reviewed a case of renal mass which was considered to be a spontaneously regressed renal cell carinoma. This diagnosis was supported by the size of the renal mass, its total necrosis, and the discovery of a few remaining tumor cells. We cautiously report this case as a spontaneously regressed primary renal cell carcinoma in a 54 year old woman.
Carcinoma, Renal Cell/pathology*
;
Female
;
Human
;
Kidney/pathology
;
Kidney Neoplasms/pathology*
;
Middle Age
;
Necrosis
;
Neoplasm Regression, Spontaneous*
6.Spontaneous regression of hepatocellular carcinoma: a case report.
Tae Jung JANG ; Jong Im LEE ; Dong Hoon KIM ; Jung Ran KIM ; Hyeon Kyeong LEE
The Korean Journal of Internal Medicine 2000;15(2):147-150
Spontaneous regression of cancer is a rare phenomenon seldom described in patients with hepatocellular carcinoma. A 54-year-old Korean woman suffered from cytologically-proved advanced hepatocellular carcinoma, for which she received no treatment. Papanicolaou's smears revealed high cellularity. Many clusters of polygonal cells showed long, thick anastomosing cords covered by flattened endothelial cells. The polygonal cells showed small hepatocytoid appearance, characterized by increased nuclear/cytoplasmic ratio. She remained in good clinical condition and, at 4 years of follow-up, the hepatocellular carcinoma could not be visualized radiologically. To date, only 14 case reports of apparently spontaneous regression of hepatocellular carcinoma have been published in the English literature. The mechanisms underlying this intriguing phenomenon remain unknown.
Carcinoma, Hepatocellular/pathology+ACo-
;
Case Report
;
Female
;
Human
;
Liver Neoplasms/pathology+ACo-
;
Middle Age
;
Neoplasm Regression, Spontaneous+ACo-
7.Pathologically Confirmed Spontaneous Partial Regression of Hepatocellular Carcinoma.
Jeong Ju YOO ; Jeong Hoon LEE ; Kyung Boon LEE ; Jae Moon KOH ; Minjong LEE ; Young Hoon CHOI ; Jung Hwan YOON
Korean Journal of Medicine 2014;86(2):198-203
Spontaneous regression of hepatocellular carcinoma (HCC) is extremely rare, and dozens of cases have been reported in the literature. In this report, we present a case of pathologically confirmed HCC that partially regressed without medical intervention. A 54-year-old Korean male with chronic hepatitis B had a hepatic mass detected by abdominal ultrasonography during a routine visit. A clinical diagnosis of HCC was made after measuring serum alpha-fetoprotein levels followed by dynamic computed tomography and magnetic resonance imaging. The patient delayed surgical resection; however, after 5 months, the size of the HCC decreased from 3.2 to 1.0 cm in diameter without any treatment. At that time the mass was surgically resected. Histopathology confirmed that the hepatic mass was consistent with partially regressed HCC and showed more intra- and peri-tumoral lymphocytes consisting of greater CD4+ T cell infiltration than what is normally seen in resected HCC.
alpha-Fetoproteins
;
Carcinoma, Hepatocellular*
;
Diagnosis
;
Hepatitis B, Chronic
;
Humans
;
Lymphocytes
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Neoplasm Regression, Spontaneous
;
Ultrasonography
8.Pathologically Confirmed Spontaneous Partial Regression of Hepatocellular Carcinoma.
Jeong Ju YOO ; Jeong Hoon LEE ; Kyung Boon LEE ; Jae Moon KOH ; Minjong LEE ; Young Hoon CHOI ; Jung Hwan YOON
Korean Journal of Medicine 2014;86(2):198-203
Spontaneous regression of hepatocellular carcinoma (HCC) is extremely rare, and dozens of cases have been reported in the literature. In this report, we present a case of pathologically confirmed HCC that partially regressed without medical intervention. A 54-year-old Korean male with chronic hepatitis B had a hepatic mass detected by abdominal ultrasonography during a routine visit. A clinical diagnosis of HCC was made after measuring serum alpha-fetoprotein levels followed by dynamic computed tomography and magnetic resonance imaging. The patient delayed surgical resection; however, after 5 months, the size of the HCC decreased from 3.2 to 1.0 cm in diameter without any treatment. At that time the mass was surgically resected. Histopathology confirmed that the hepatic mass was consistent with partially regressed HCC and showed more intra- and peri-tumoral lymphocytes consisting of greater CD4+ T cell infiltration than what is normally seen in resected HCC.
alpha-Fetoproteins
;
Carcinoma, Hepatocellular*
;
Diagnosis
;
Hepatitis B, Chronic
;
Humans
;
Lymphocytes
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Neoplasm Regression, Spontaneous
;
Ultrasonography
9.Spontaneous Regression of a Cystic Tumor in a Postpartum Woman; Is It A Cystic Lymphangioma?.
Seung Ho JOO ; Myeong Jin KIM ; Ki Whang KIM ; Woo Jung LEE ; Mi Suk PARK ; Joon Seok LIM
Yonsei Medical Journal 2007;48(4):715-718
Spontaneous regression of intra-abdominal cystic tumors in adults is unusual. Here, we present the case of an apparently spontaneous regression of a large intra-abdominal cystic mass found in the postpartum period of an 18-year-old woman. The regression was demonstrated using serial computed tomography (CT) examinations over a two-year period.
Abdominal Neoplasms/*radiography
;
Adolescent
;
Female
;
Humans
;
Lymphangioma, Cystic/*radiography
;
*Neoplasm Regression, Spontaneous
;
Postpartum Period
;
Tomography, X-Ray Computed
10.Spontaneous Regression of a Cystic Tumor in a Postpartum Woman; Is It A Cystic Lymphangioma?.
Seung Ho JOO ; Myeong Jin KIM ; Ki Whang KIM ; Woo Jung LEE ; Mi Suk PARK ; Joon Seok LIM
Yonsei Medical Journal 2007;48(4):715-718
Spontaneous regression of intra-abdominal cystic tumors in adults is unusual. Here, we present the case of an apparently spontaneous regression of a large intra-abdominal cystic mass found in the postpartum period of an 18-year-old woman. The regression was demonstrated using serial computed tomography (CT) examinations over a two-year period.
Abdominal Neoplasms/*radiography
;
Adolescent
;
Female
;
Humans
;
Lymphangioma, Cystic/*radiography
;
*Neoplasm Regression, Spontaneous
;
Postpartum Period
;
Tomography, X-Ray Computed