1.Juvenile Granulosa Cell Tumor of the Ovary: Report of a Case of Malignant Form with Unusual Pleomorphism.
Chong Jai KIM ; Jin Suk SUH ; Sung Hye PARK ; Je G CHI
Korean Journal of Pathology 1990;24(3):316-320
A case of Juvenile Granulosa Cell Tumor (JGCT) of the ovary with unusual pleomorphic histologic and malignant biologic behaviour is described. The tumor occurred in a 10-year-old girl and was associated with clinical features of isosexual pseudoprecosity and a marked elevation of serum estradiol. The mass manifested initially in the right ovary and subsequently involved the contralateral ovary. A multi-organ metastasis developed during a 6-month-interval despite chemotherapy. She received two operations at 6-month interval, and tissues were obtained from the tumor mass. A marked histologic difference was observed between these two samples. The second biopsy showed profound cellular pleomorphism with numerous multinucleated tumor giant cell formation and hyaline bodies. The differential diagnosis from germ cell tumor and the possible factors for the pleomorphism are discussed.
Diagnosis, Differential
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Biopsy
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Neoplasm Metastasis
2.Clinical and paraclinical features of primary liver cancer
Journal of Vietnamese Medicine 2001;263(9):54-57
Primary liver cancer occurs frequently in male. It has a fatal outcome within the first 6 months and deaths are mainly due to coma and cachexia. 3 initial symptoms are often seen: anorexia, pain under the right costal margin and diarrhea. Liver cancer occurs frequently on a cirrhotic liver. Mass cancer and nodular cancer are the prevailing forms. Microscopically, hepatocellular carcinoma is the predominant picture. Metastasis to the liver pedicle nodes is often noted and distant metastasis is uncommon
Liver Neoplasms
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Neoplasm Metastasis
;
diagnosis
3.Solitary Cerebellar Metastasis from Primary Uterine Cervical Carcinoma: A Case Report.
Jeong Ha PARK ; Chang Seong CHO ; Kwan Young SONG ; Eun Joo HA ; Yun Kyung HAHN ; Choong Hyun KIM ; Youn Il HA
Journal of Korean Neurosurgical Society 1996;25(8):1668-1672
Brain metastasis from primary uterine cervical carcinoma have been described but are extremely rare and usually occur in the presence of widely disseminated diseases. The authors report a case of solitary cerebellar metastasis from uterine cervical carcinoma, which was confirmed by histopathological examination. The patient has shown no evidence of metastatic lesions elsewhere, thus far, but had undergone a radical hysterectomy under the diagnosis of uterine cervical carcinoma 52 months prior to the surgical excision of the cerebellar metastasis.
Brain
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Diagnosis
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Humans
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Hysterectomy
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Neoplasm Metastasis*
4.A Case of Metastatic Malignant Melanoma of the Gallbladder.
Tae Hoon KIM ; Jin Young JANG ; Min Gew CHOI ; Yoo Seok YOON ; Sun Whe KIM ; Yong Hyun PARK
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2004;8(3):198-201
A metastatic melanoma is a ubiquitous tumor that spares no organ from metastases. Gastrointestinal involvement is a common occurrence in patients with a metastatic melanoma, and post mortem records have shown gallbladder involvement in about 15% of all gastrointestinal metastatic localizations. However, metastasis to the gallbladder as an isolated site is rare. Herein, an unusual case of a young man in whom a single metastatic gallbladder melanoma was the first and only metastatic site of the disease is reported. The clinical presentation, diagnosis, histopathology, prognosis and treatment of metastatic melanomas of the gallbladder are also reviewed.
Diagnosis
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Gallbladder*
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Humans
;
Melanoma*
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Neoplasm Metastasis
;
Prognosis
5.HRCT findings of pulmonary metastases.
Sang Hee CHOI ; Ki Nam LEE ; Seok Hyun SON ; Kyung Jin NAM ; Byeong Ho PARK ; Duck Hwan CHUNG
Journal of the Korean Radiological Society 1993;29(5):981-986
The authors retrospectively reviewed the high resolution computed tomographic scans of 19 patients who had hematogenous or lymphangitic metastatic lung lesions. In all patients, the histologic diagnosis for primary cancers and the radiographic manifestations of pulmonary metastasis were established. Certain characteristic findings of metastatic lung tumors on HRCT scans were evident: uneven thickening of bronchovascular bundles, multiple small nodules, thickening of interlobular septum, and the presence of polygonal lines. The nodules are more predominent in hematogenous metastasis. The prevalent site of nodules is cortical portion of lung.
Diagnosis
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Humans
;
Lung
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Neoplasm Metastasis*
;
Retrospective Studies
6.The Expression of c-myc and AAT in Gastric Carcinoma.
Sun Mi PARK ; Ho Dae YOU ; Pok Keun KIM ; Won Sup OHO ; Seon Ja PARK ; Man Ha HUH ; Ja Young KOO
Journal of the Korean Cancer Association 1997;29(5):774-784
PURPOSE: We have conducted this study to investigate the role of c-myc and AAT in gastric carcinoma progression and to see if clinical application of its expression in cancer tissue is of help for the diagnosis or in determining prognosis of gastric carcinoma. MATERIALS AND METHOD: The expression of c-Myc and AAT by immunohistochemical method applied to paraffin-embedded tissue sections of endoscopic biopsy materials of 71 cases of gastric carcinoma (24 early and 47 advanced) and immunoreactivities of antigens were correlated with histological differentiation of carcinoma, degree of tumor infiltration of mononuclear cells, serum levels of carcinoembryonic antigen (CEA) and presence of distant metastases. RESULTS: c-Myc in gastric carcinoma tissue was expressed in 24 cases (33.8%), and the rate of immunoreactivity of c-Myc was higher in the advanced carcinoma cases (38.2%) than early carcinoma cases (25.0%), but the difference was not stastistically significant. The elevated c-Myc expression correlated well with the elevation of serum CEA levels (P<0.05), with the presence of distant metastses (p<0.05), especially with peritoneal metastsis (p<0.05). AAT expression in gastric carcinoma was shown in 11 cases (14.1%), and the rate of immunoreactivity of AAT was significantly higher in advanced carcinoma cases (21.3%) than early carcinoma cases (4.2%) (p<0.05). The elevated expression of AAT correlated well with the elevation of serum CEA levels (p<0.05), and showed negative correlation with the degree of mononuclear cell infiltration in tumor area (p<0.05). The increased expression of c-Myc and AAT in gastric carcinoma correlated well (p=0.05, k= 0.31), which suggests the cooperative action of the two in gastric carcinoma progression. CONCLUSIONS: Our findings suggest that c-Myc expression may be a good marker of high grade malignancy in gastric carcinoma, and may be able to be used clinically in predicting distant metastases, especially for peritoneal dissemination. Our data also imply that c-myc, through its proliferative action, may play an important role in the progression of gastric carcinoma in cooperation with AAT which has immunosuppresive action.
Biopsy
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Carcinoembryonic Antigen
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Diagnosis
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Neoplasm Metastasis
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Prognosis
7.Cutaneous Metastasis Presenting as an Indurated Plaque Preceding the Diagnosis of Lung Adenocarcinoma.
Eo Gin LEE ; Kyu Young SEO ; Sang Eun LEE ; Hee Jung LEE ; Moon Soo YOON
Korean Journal of Dermatology 2014;52(1):59-60
No abstract available.
Adenocarcinoma*
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Diagnosis*
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Lung Neoplasms
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Lung*
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Neoplasm Metastasis*
8.A case of primary leiomyosarcoma of the mesentery with hepatic metastasis.
Ho Ah KIM ; Sang Il PARK ; Heung Seop SONG ; Mung In KIM ; Beob Jong KIM ; Moon Hong KIM ; Suck Chul CHOI ; Sang Young RYU ; Eui Don LEE ; Kyung Hee LEE ; Soo Yung JUNG
Korean Journal of Gynecologic Oncology 2005;16(3):264-267
Primary tumors of the mesentery are uncommon, and primary leiomyosarcoma of the mesentery is especially rare, and thus an accurate preoperative diagnosis is difficult. We experienced a case of 32-year female with primary leiomyosarcoma of the mesentery. We report this case with a brief review of the literature.
Diagnosis
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Female
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Humans
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Leiomyosarcoma*
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Mesentery*
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Neoplasm Metastasis*
9.Primary Malignant Melanoma of the Esophagus: A Case Report.
Jae Wook LEE ; Mi Suk PARK ; Ki Whang KIM ; Ju Yeon PYO ; Seung Hwan CHA ; Joon Seok LIM ; Myeong Jin KIM
Journal of the Korean Radiological Society 2007;57(1):37-41
Primary malignant melanoma of the esophagus is extremely rare, with less than 200 cases reported in the literature. However, primary malignant melanoma is an aggressive tumor. We report a case of primary esophageal malignant melanoma that presented with a large polypoid mass in the lower esophagus, and subsequently showed multiple metastatic nodules in the subcutaneous layer, skin and retroperitoneum. Primary malignant melanoma should be included in the differential diagnosis of a polypoid esophageal mass, especially in cases where metastases to unexpected areas occur or in cases of unexpected metastatic patterns.
Diagnosis, Differential
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Esophagus*
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Melanoma*
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Neoplasm Metastasis
;
Skin
10.Bone scan for diagnosis of metastasis induced bone cancer
Journal of Vietnamese Medicine 1999;233(2):54-57
During 1994-1997, the nuclear medicine department of Cho Ray hospital diagnosed clinically 1938 patients with the cancer and implemented the scintigraphy to discover the metastasis. 816 patients with the cancer with the high risk of metastasis including the breast cancer, vaginal cancer, lung cancer, prostate gland cancer and thyroid cancer which arranged as kind of cancer and age. The bone scintigraphy help classifying the cancer with metastaisi and the comparision of the rate of metastasis into bone in this study with this rate reported by the Utrecht University of Ha Lan.
Bone Neoplasms
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diagnosis
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Neoplasm Metastasis
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Bone and Bones