No abstract available.
Neoplasm, Residual*

No abstract available.
Leukemia* ; Neoplasm, Residual*

No abstract available.
Gallium* ; Neoplasm, Residual* ; Wounds and Injuries*

Interpretation of the pathologic margin of a specimen from a resected tumor is important because local recurrence can be predicted by the presence of tumor cells in the resection margin. Although a sufficient resection margin is recommended in the resection of gastrointestinal adenocarcinoma, it is not usually regarded strictly in cases of mesenchymal tumor, especially gastrointestinal stromal tumor (GIST), because the tumor is usually encapsulated or well demarcated, and not infiltrative. Therefore, margin positivity is not rare in the pathological evaluation of surgically or endoscopically resected GIST, and does not always indicate incomplete resection. Although a GIST may have a tumor-positive pathologic margin, complete resection may be achieved if no residual tumor is visible, and long-term survival can be predicted as in the cases with a negative pathologic margin.
Adenocarcinoma ; Gastrointestinal Stromal Tumors* ; Neoplasm, Residual ; Recurrence

This report describes the usefulness of positron emission tomography-computed tomography (PET-CT) for evaluating recurrent or residual tumors following surgery. CT and 18F-fluorodeoxyglucose PET-CT were pre- and post-operatively applied to multiple masses in a dog with hemangiosarcoma. The distinction between the left subcutaneous mass and the peritoneum was clarified on pre-operative CT examination, and malignancy was suspected based on PET-CT. A recurrent or residual tumor in the left subcutaneous region was suspected on post-operative PET-CT, and confirmed through histopathologic examination.
Animals ; Dogs ; Electrons* ; Hemangiosarcoma* ; Neoplasm, Residual ; Peritoneum

BACKGROUND: The principle of Mohs micrographic surgery is to examine microscopically the entire peripheral margin of an excised tissue specimen to precisely localize the site of any residual tumor and enable its subsequent removal. In processing in the tissue for frozen horizontal sections, a technical difficulty arises in manipulating the deep and lateral margins into the same flat plane. OBJECTIVE: Our aim was to develop a new method allowing the optimal tissue preperation for Mohs micrographic smgery and to evaluate the usefulness of this methad. METHODS: The technique involves conversion of a non-planar surgical margin to a planar surface by applying and freezing the specimen against a flat glass surface. We compared this modified method used in our laboratory with standard methods for tissue preparation of Mohs micrographic surgery.
Freezing ; Glass ; Mohs Surgery ; Neoplasm, Residual

In prostate cancer patients without local invasion and metastasis, radical prostatectomy is performed as a rule for the resection of residual cancer. In a few cases, little amount of cancer volume is identified in radical prostatectomy specimens. This finding has been described as 'minimal residual cancer' or 'vanishing cancer phenomenon' and some reports have demonstrated an increase in the incidence of minimal residual prostate cancer. However, only few cases with 'minimal residual cancer' or 'no residual cancer' despite efforts searching for other possibilites have been reported. We report a case of no residual cancer in radical prostatectomy specimens of biopsy-proven prostate cancer.
Humans ; Incidence ; Neoplasm Metastasis ; Neoplasm, Residual* ; Prostate* ; Prostatectomy* ; Prostatic Neoplasms*

Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.
Accounting ; Hypercalcemia ; Hyperparathyroidism ; Neoplasm, Residual ; Parathyroid Hormone ; Parathyroid Neoplasms ; Recurrence

OBJECTIVE: This study was performed to evaluate the diagnostic accuracy of cytology, colposcopically directed biopsy and conization and to analyze predictive factors for residual tumor after conization in patients with cervical neoplasia. METHODS: We reviewed 167 patients who had undergone cytology, colposcopically directed biopsy and conization followed by subsequent hysterectomy depending on their current disease status at the Department of Obstetrics & Gynecology, Catholic University of Korea Medical College, Holy Family Hospital from January, 1993 to August, 1998. The diagnostic accuracy of cytology, colposcopically directed biopsy and conization were investigated. Also, we investigated the significance of the margin status and the presence of HPV which were used to predict residual tumors in hysterectomy specimens after conization. RESULTS: The results of each methods were analyzed with regard to the histopathologic findings of the surgical specimen. The accuracy rates of cytology, and colposcopically directed biopsy were 59.3% (99 of 167) and 71.3% (119 of 167), respectively. After conization, residual tumors were found in 30.1% of subsequent hysterectomized specimens (51 of 167). Underestimation by conization occurred in 2.0% of cases (1 of 51) and overestimation in 7.8% (4 of 51). Residual tumors were significantly more frequent in patients with positive conization margins than in those with negative margins (P<0.001). But the presence of HPV was not significant. CONCLUSION: These results suggest that diagnostic conization seems to be essential procedure in patients showing abnormal results by cytology and colposcopically directed biopsy, especially in those with CIN III or microinvasion, for the further proper management of cervical neoplastic lesion and margin status is useful in predicting residual tumor after conization.
Biopsy* ; Conization* ; Gynecology ; Humans ; Hysterectomy ; Korea ; Neoplasm, Residual* ; Obstetrics

OBJECTIVE: To evaluate the significance of the expression of HER-2/neu oncoprotein as a prognostic factor, we retrospectively examined its overexpression rates in epithelial ovarian cancer and their relationships with prognostic factors. METHODS: Immunohistochemistry for Her-2/neu oncoprotein was performed on formalin-fixed, paraffin-embedded tissues from 45 epithelial ovarian cancer operated between 1999 and 2002. We analyzed relationships between the overexpression of HER-2/neu oncoprotein and prognostic factors including age, histologic type, surgical stage, residual tumor > or =2 cm, and recurrence. RESULTS: The rate of overexpression of HER-2/neu oncoprotein in epithelial ovarian cancer was 31.1% (14/47). The overexpression of HER-2/ neu oncoprotein showed associations with residual tumor > or =2 cm (p=0.049) and recurrence (p=0.029) in univariate analysis. But, there were no associations between the overexpression of HER-2/neu oncoprotein and overall survival. CONCLUSION: The overexpression of HER-2/neu oncoprotein was associated with residual tumor and recurrence in univariate analysis, but appeared to have no prognostic significance for overall survival of epithelial ovarian cancer. Further and larger prospective studies using multivariate analysis are necessary to establish the clinical applicability of these observations.
Immunohistochemistry ; Multivariate Analysis ; Neoplasm, Residual ; Ovarian Neoplasms* ; Recurrence ; Retrospective Studies