We present a case of nasopharyngeal carcinoma complicated with hyperleucocytosis. After ruling our other causes we concluded that the hyperleucocytosis was due to paraneoplastic leukemoid reaction (PLR). The overall survival was 15 months which is rare among patients with PLR
Nasopharyngeal Neoplasms

No abstract available.
Nasopharyngeal Neoplasms*

Studying the dynamy of immunobiological parameters after radiotherapy and estimating its prognostic values on 77 NPC patients with T1-3No-3Mo (UICC 1979) at Hanoi K hospital from 11/1994 to 12/1998. We have some results: The prognostic values have been found significantly in the quantity of leukocytes, the level of serum IgA/VCA, IgG/EBNA before radiotherapy, the frequency of HLA antigens A11, A2, B17 and the desequilibre linkage A11-B17, A2-B17. Especially, the increase of serum IgA/VCA after radiotherapy has significantly predicted recurrence of studied NPC patients
Nasopharyngeal Neoplasms ; Nasopharyngeal Diseases ; Radiotherapy

No abstract available.
Induction Chemotherapy* ; Nasopharyngeal Neoplasms*

1.The incorrect diagnosis ratio: 11.22%, less than our retrospective analysis; 31.25% and other reported analysis: 28.08-35%. 2.Overcoming used methods: endoscopic examination and biopsy; DNA extraction from tumor sample and PCR-EBV with primer EBNA2A, additionally by Dot Blot hybridization in accordance with ECL protocol and technique (Amersham RPN-3000). Obtained results of investigated 31 NPC patients showed that: 27/28 case with Undifferentiated carcinoma Nasopharyngeal Type (UCNT): (96.43%) are in conformity with histology, of which 2/27 cases (7.40%) are positive before histological diagnosis (6 months and 9 months). 1/28 cases (3.75%) are not in conformity with histology. In all 3 cases with Spinocellular carcinoma (S.C): (100%) the DNA-EBV is negative in tumor samples.
Nasopharyngeal Neoplasms ; Endoscopy

EVB DNA fragments from 3 biopsies obtained from Vietnamese patients with NPC have been examined by PCR detection method, using a mixture of primers TH1,2. PRC products were cloned by using vector PCM TM II and were sequenced on Automated sequencer. The result showed that our PCR products were similar to the specific sequence of EBV have been reported in EMBL data library, confirmed that PCR products are specific fragments of EBV, we can successfully use the mixture of primers TH1,2 in PCR detection of EBV DNA in biopsies of NPC patients
Nasopharyngeal Neoplasms ; Base Sequence

15 patients with NPC were diagnosed by pathology were undifferentated carcinoma. The authors used the indirected immuno-fluorescent technique with the monoclonal antibody to determine HLA class I at squarmous cell of NPC tissue. HLA class I expressed weakly: 2112.8% Pan ABC; 10.838.37% B2M. There was a correlation between the prognosis groups and expressing of HLA class I
Nasopharyngeal Neoplasms ; Carcinoma ; Diagnosis

By the technique of indirect immunofluoresceine using 18 diverse markers, in the hospital K- Ha Noi, study was performed to determine the capacity of foreign antigene expression of tumor cells in the cell surface making them identified by immunology system through HLA system on NPC < 75 years old age patients. This system played an essential role in the regulation and realization of immune response.
Carcinoma ; Nasopharyngeal Neoplasms ; Nasopharyngeal Diseases ; Diagnosis

p style=text-align: justify;strongOBJECTIVE: /strongTo describe a case of nasopharyngeal carcinoma coexistent with primary nasopharyngeal tuberculosis and review the literature.METHODS:br /Design:/strong Case Reportbr /strongSetting:/strong Tertiary Public University Hospitalbr /strongPatient:/strong One RESULTS:/strong A 28-year-old man presented with recurrent sore throat and neck pain with clinically enlarged tonsils. He underwent a routine adenotonsilectomy. Histopathologic examination revealed non-keratinizing squamous cell carcinoma with caseating granulomatous inflammation typical for tuberculosis in the same adenoid specimen. Nasopharyngeal carcinoma was staged T2bN2M0. He was treated with concurrent chemoradiotherapy and 9-month course of anti tuberculosis treatment. He recovered and remained symptom free year after treatment.CONCLUSION: /strongNasopharyngeal carcinoma (NPC) and tuberculosis (TB) are both very common diseases in Sabah, East Malaysia. However, it is very rare that both diseases present at the same time and same anatomical area in a patient. Diagnosis can be very challenging and confusing. Multidisciplinary consultations are warranted for appropriate treatment. Combined anti-tuberculosis treatment and concurrent chemoradiotherapy may be appropriate and effective./p
Human ; Male ; Adult ; Nasopharyngeal carcinoma ; Nasopharyngeal Neoplasms

Artificial Intelligence ; Humans ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms