Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tractinfection. Most surgical site infections occur after discharge from the hospital and increasingly beingused as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidencebasedguidelines recommended the use of prophylactic antibiotics before surgical incision. An exceptionis made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cordclamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision,broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage tothe neonate. The beneficial effect of prophylactic antibiotics in reducing the occurrence of infectiousmorbidity form caesarean section, whether elective or emergency is well established. A single dose offirst-generation cephalosporin is as effective as multiple doses of broad-spectrum agents. Prophylacticantibiotics for caesarean section are commonly used worldwide, and in most institutions a single dose isadministered, generally after clamping of the umbilical cord. However, a recent survey (published in 2011)of maternal and fetal medicine physicians in the USA revealed that 84% of those who responded (theresponse rate was 25%) used preoperative administration. The effectiveness of prophylactic antibioticsdepends on their presence in effective concentrations throughout the operative period. Classen et al.found that administration of prophylactic antibiotics within a 2-hour period preoperatively was associatedwith the lowest surgical wound infection rate. Because of concerns about unnecessary fetal exposure,masking of fetal infection, increases in neonatal septic work-up and the emergence of resistant strainswhen prophylactic antibiotics are given preoperatively, it is a common obstetric practice to administerprophylactic antibiotics after cord clamping.Conclusion:1. Probability for occurring wound infection happens in case of urgent caesarean delivery for patientswho have not administered by preventative antibiotic.2. It has been confirmed that preventative antibiotic administration is proper in special occasions ofcaesarean delivery for women who suffer from anaemia obesity, diabetes, or chronic inflammatorydisease prior to their delivery.3. When preventative antibiotic administration is used 60 minutes before the caesarean delivery,concentration in blood and tissue reaches up to the maximum amount.

Background: High blood pressure is both a cause and a complication of chronic kidney disease. As complication, high blood pressure may develop early during course of chronic kidney disease and is associated with adverse outcomes, in particular faster loss of kidney function and development of cardiovascular disease. The purpose of this study is early detection of chronic kidney disease in patients with hypertension by defining the prevalence of microalbuminuria.Methods: The study population consisted of 169 subjects with a hypertension. Individuals were considered to have hypertension if the blood pressure measured greater than 140/90 mmHg or if they were taking blood pressure lowering medications. Microalbuminuria was defined as 20 mg/l or greater. Results: We are presenting data on 169 subjects :male 38 (22.5%) female 131 (77.5%), average age 51.6±0.89 At screening, 14.8% of all participants were smokers, 62.1 % engaged in low levels of physical activity, 72.8% - were having tea with salt (table1). Microalbuminuria and renal failure, as GFR<60 ml/ min/1.73 m2, were documented in 34.3% and 16.6% of subjects, respectively. There is positive correlation between MAU and increasing-range of blood pressure (table2). Correlation was found between albuminuria and GFR(r= -0.2 p<0.01) and serum creatinine(r=0.31 p<0.01) the regression result has shown that GFR is associated with MAU and serum creatinine (table 3).Conclusions:1. In 34.3% of patient with hypertension was found nephropathies with MAU2. Microalbuminuria is increased with decline of GFR and raise of systolic blood pressure. GFR decline is with the raise of age and serum. It is important to implement in clinical practice screening of MAU hypertensive patients.3. In 2/3 of all screened subjects was found 1 and more risk factors for CVD.