BACKGROUND: The study is a post-marketing surveillance study conducted for a one month period, with two visits at two-week intervals.

METHODOLOGY: The design was prospective, open-label and observational, which included adult patients 18 years old and above, diagnosed with mild to moderate hypertension, requiring treatment with anti-hypertensive. Data collected were analyzed descriptively. Heart rate and systolic and diastolic BP were described by the total number of observations, mean and standard deviation. Efficacy and safety were determined and student's t-test was used to calculate statistical significance.

RESULTS/CONCLUSION: At the end of the study period, S(-) amlodipine was found to a have positive effect on heart rate and both systolic and diastolic blood pressure and this effect is sustained over four weeks. A very low of transient adverse events were recorded, with headache still the most common.

Human ; Male ; Female ; Aged 80 and over ; Aged ; Middle Aged ; Adult ; Adolescent ; Amlodipine ; Safety ; Treatment Outcome ; Hypertension