1.Epidemiological survey of Helicobacter pylori infection and analysis of related factors among adult population receiving physical examination in Yunnan plateau area
Demei JIA ; Qiang WANG ; Nanjiang CHU ; Tingting CHEN ; Qun FENG ; Yunfan GU
Chongqing Medicine 2018;47(7):950-956
Objective To survey the infection status and related factors of Helicobacter pylori(H.pylori) among adult population receiving physical examination in Yunnan plateau area so as to provide a basis for control and treatment of H.pylori infection at the present stage.Methods The epidemiological survey method was applied to collect the intact data on adult health physical examination from Jan.2013 to Feb.2015,including the results of survey by adopting the unified national questionnaire and 13 C-urea breathe test for detecting H.pylori.The guestionniare contents had the basic conditions,socid economy stalus,personal and family health status cinecluding whether sufferring from digestive diseases or symptoms,dietary habit,etc.Results A tatae of 1 680 eligi ble subjects were included in this study.The total infection rate of H.pylori was 33.5%,which of male and female were 33.2% and 34.5 % respectively,the difference was not statistically significant (P>0.05).The peak of H.pylori infection rate was in the age group 40-49 years(36.7 %),but the difference among different age groups had no statistical significance(P>0.05).The univariate analysis indicated that H.pylori infection was not correlated with nationality,permanent residence,occupation,education level,marital status and number of living together members(P>0.05);H.pylori infection had no correlation with whether the individual or family members having digestive system disease or symptoms(P>0.05);washing hands before meals and after defecation,stress of work,living and study,mainly used latrine type,daily means of transportation,work and rest time,sharing cutlery,diets habits,brushing teeth frequency per day and source of drinking water had no influence on H.pylori infection(P>0.05),and smoking,alcohol drinking and frequently contacting with animals also had no influence on H.pylori infection(P>0.05).H.pylori infection was significanly correlated with the social economical status,daily means of transportation and alcohol drinking(P<0.05).The multiple unconditional Logistic regression analysis results indicated that there was negative correlation between H.pylori infection and monthly income,the OR (95%CI)value was 0.848(0.759-0.949).Conclusion The H.pylori total infection rate in adult population receiving physical examination in Yunnan plateau area is lower than the national population natural infection rate.It should focus on middle-aged population and low-income people.
2.Correlation between Helicobacter pylori infections and serum lipid abnormality in adult population of healthy physical examination
Demei JIA ; Qiang WANG ; Nanjiang CHU ; Tingting CHEN ; Yunfan GU ; Qun FENG
Chongqing Medicine 2018;47(10):1325-1328
Objective To explore the relationship between Helicobacter pylori (HP) infection and dyslipidemia in adult people undergoing the healthy physical examination in Kunming city.Methods The intact population data of adult people undergoing the healthy physical examination and conducting the HP detection by adopting the 13C breath test (13 C-UBT)in the Cadres Physical Examination Center,Yunnan Provincial Second People's Hospital from January 2013 to February 2015 were retrospectively analyzed.The data included the basic information and serum fipids indexes[total cholesterol (TC),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C)].All subjects were divided into the HP positive group and HP negative group according to whether having HP infection.The levels of TC,TG,HDL-C,LDL-C and the incidences of single index of dyslipidemia and total dyslipidemias were compared between 2 groups and Logistic regression analysis was performed for investigating the relationship between HP infection and dyslipidemia.Results A total of 1 354 subjects were included in the study.The HP infection rate was 33.2%.The levels of TC,TG,HDL-C and LDL-C were no statistical significance between positive HP group and negative HP group (P>0.05).The incidence rate of TC≥6.22 mmol/L of HP positive group was lower than that of HP negative group (P<0.05).The occurrence rate of TC increase abnormality in the HP positive group was lower than that in the HP negative group (P<0.05);the occurrence rate of dyslipidemia had no statistical difference between the HP positive group and HP negative group in the stratification according to sex,age and BMI (P>0.05).The regression analysis showed that the HP infection was an independent influencing factors of TC increase abnormality (OR=0.644,P<0.05).Conclusion The HP infection affects the incidence of TC increase abnormality,but might not affect the occurrence rate of dyslipidemia.
3.The epidemiological investigation of major depressive disorder and dysthymia in mosuo ethnic minority of Ninglang area, Yunnan province
Li XU ; Qiang WANG ; Jinmei YANG ; Yuanyuan LIN ; Haiyin ZHANG ; Guohua FENG ; Xianwei ZENG ; Hua ZHONG ; Fang CHEN ; Nanjiang CHU ; Jing YUAN ; Yan ZHANG ; Yujun WEI ; Fang ZHOU ; Jianzhong YANG
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(8):758-762
Objective To explore the prevalence of depressive disorder in the Mosuo ethnic minority in Ninglang district,Yunnan Province.Methods By stratified random sampling,1 121 Mosuo subjects aged 15 or above were selected and assessed by the MINI-international neuropsychiatric interview according to the Structured Clinical Interview for DSM-V-TR Axis I Disorders-Patient Edition for mental disorders.Results The standardized time-point prevalence of major depressive disorder in Mosuo nationality was 1.74%,and 1.69% (95 % CI =1.32%-2.15 %) in males and 1.77% (95 % CI =1.39%-2.15 %) in females.There was no statistically significant difference in the prevalence of major depressive disorder between males and females (x2 =0.051,P>0.05).The standardized time-point prevalence of dysthymic disorder in Mosuo nationality was 0.78%,and 0.66% (95% CI=0.54%-0.78%) in males and 0.88% (95% CI=0.74%-1.02%) in females (x2=1.232,P>0.05).Those aged 40-54 years old had the highest adjusted prevalence of depressive episodes(1.48% (95%CI=0.77%-2.18%)).Conclusion The prevalence of depressive disorder in Mosuo nationality is in a low level,and the middle-age Mosuo people has the highest time-point prevalence.