OBJECTIVE:To evaluate the clinical outcome of arterial perfusion with chemotherapy medicine together with elemenum emulsion injection solution via Port-Catheter System(PCS)in treating middle-late malignant tumors.METHODS:A total of63patients with middle-late malignant tumors were enrolled,31were randomly assigned to receive arterial perfusion of chemotherapeutics in combination with elemenum emulsion(group A),and32cases to receive single arterial perfusion of chemotherapeutics(group B),the short-term curative effects of the2groups were then compared.RESULTS:The total effec_ tive rate of group A and B were66.7%and46.7%,respectively with one-year survival of which respectively at56.7%and43.3%.There was significant difference between two groups(P

Objective To investigate the electrocardiogram and clinical data of people taking cough syrup or addicted to heroin. Methods A total of 450 people took cough syrup or addicted to heroin who were treated in the addiction medicine department of our hospital were collected from December 2007 to December 2011 and divided into two groups according to the addition type, with 200 cases in the cough syrup group and 250 cases in the heron group, and the con-trol group consists of 200 normal healthy persons. The patients' fasting glucose, total cholesterol, serum triglycerides, blood low-density lipoprotein cholesterol, blood high-density lipoprotein cholesterol, blood pressure and electrocardio-gram were recorded. Results The cough syrup group compared with the heroin group, the control group had higher hemoglobin, total cholesterol, triglycerides, systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol and low density lipoprotein cholesterol, with statistically significant differences (P<0.05); Compared with the cough syrup group, the heroin group had lower hemoglobin, total cholesterol, triglycerides, systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol and low density lipoprotein cholesterol, with statistically significant differences (P<0.05); The control group had the lowest incidences of bradycardia, sinus tachycardia, prema-ture atrial contraction, premature ventricular contraction, left anterior branch conduction block, left posterior branch conduction block, atrioventricular conduction block, ST-T change, limb leads low voltage, QT interval prolongation change, complete right bundle branch block and incomplete right bundle branch block, and the heroin group had the highest incidences, with statistically significant differences (P<0.05). Conclusion Of the 3 groups, the heroin group has the severest myocardial and biochemical damage and the cough syrup group also has varying degrees of damage. Anti-drug publicity should be strengthened in order to improve the awareness of drug harm.

Objective To survey the infection status and related factors of Helicobacter pylori(H.pylori) among adult population receiving physical examination in Yunnan plateau area so as to provide a basis for control and treatment of H.pylori infection at the present stage.Methods The epidemiological survey method was applied to collect the intact data on adult health physical examination from Jan.2013 to Feb.2015,including the results of survey by adopting the unified national questionnaire and 13 C-urea breathe test for detecting H.pylori.The guestionniare contents had the basic conditions,socid economy stalus,personal and family health status cinecluding whether sufferring from digestive diseases or symptoms,dietary habit,etc.Results A tatae of 1 680 eligi ble subjects were included in this study.The total infection rate of H.pylori was 33.5％,which of male and female were 33.2％ and 34.5 ％ respectively,the difference was not statistically significant (P＞0.05).The peak of H.pylori infection rate was in the age group 40-49 years(36.7 ％),but the difference among different age groups had no statistical significance(P＞0.05).The univariate analysis indicated that H.pylori infection was not correlated with nationality,permanent residence,occupation,education level,marital status and number of living together members(P＞0.05);H.pylori infection had no correlation with whether the individual or family members having digestive system disease or symptoms(P＞0.05);washing hands before meals and after defecation,stress of work,living and study,mainly used latrine type,daily means of transportation,work and rest time,sharing cutlery,diets habits,brushing teeth frequency per day and source of drinking water had no influence on H.pylori infection(P＞0.05),and smoking,alcohol drinking and frequently contacting with animals also had no influence on H.pylori infection(P＞0.05).H.pylori infection was significanly correlated with the social economical status,daily means of transportation and alcohol drinking(P＜0.05).The multiple unconditional Logistic regression analysis results indicated that there was negative correlation between H.pylori infection and monthly income,the OR (95％CI)value was 0.848(0.759-0.949).Conclusion The H.pylori total infection rate in adult population receiving physical examination in Yunnan plateau area is lower than the national population natural infection rate.It should focus on middle-aged population and low-income people.

Objective To explore the relationship between Helicobacter pylori (HP) infection and dyslipidemia in adult people undergoing the healthy physical examination in Kunming city.Methods The intact population data of adult people undergoing the healthy physical examination and conducting the HP detection by adopting the 13C breath test (13 C-UBT)in the Cadres Physical Examination Center,Yunnan Provincial Second People's Hospital from January 2013 to February 2015 were retrospectively analyzed.The data included the basic information and serum fipids indexes[total cholesterol (TC),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C)].All subjects were divided into the HP positive group and HP negative group according to whether having HP infection.The levels of TC,TG,HDL-C,LDL-C and the incidences of single index of dyslipidemia and total dyslipidemias were compared between 2 groups and Logistic regression analysis was performed for investigating the relationship between HP infection and dyslipidemia.Results A total of 1 354 subjects were included in the study.The HP infection rate was 33.2％.The levels of TC,TG,HDL-C and LDL-C were no statistical significance between positive HP group and negative HP group (P＞0.05).The incidence rate of TC≥6.22 mmol/L of HP positive group was lower than that of HP negative group (P＜0.05).The occurrence rate of TC increase abnormality in the HP positive group was lower than that in the HP negative group (P＜0.05);the occurrence rate of dyslipidemia had no statistical difference between the HP positive group and HP negative group in the stratification according to sex,age and BMI (P＞0.05).The regression analysis showed that the HP infection was an independent influencing factors of TC increase abnormality (OR=0.644,P＜0.05).Conclusion The HP infection affects the incidence of TC increase abnormality,but might not affect the occurrence rate of dyslipidemia.

Objective To explore the prevalence of depressive disorder in the Mosuo ethnic minority in Ninglang district,Yunnan Province.Methods By stratified random sampling,1 121 Mosuo subjects aged 15 or above were selected and assessed by the MINI-international neuropsychiatric interview according to the Structured Clinical Interview for DSM-V-TR Axis I Disorders-Patient Edition for mental disorders.Results The standardized time-point prevalence of major depressive disorder in Mosuo nationality was 1.74％,and 1.69％ (95 ％ CI =1.32％-2.15 ％) in males and 1.77％ (95 ％ CI =1.39％-2.15 ％) in females.There was no statistically significant difference in the prevalence of major depressive disorder between males and females (x2 =0.051,P＞0.05).The standardized time-point prevalence of dysthymic disorder in Mosuo nationality was 0.78％,and 0.66％ (95％ CI=0.54％-0.78％) in males and 0.88％ (95％ CI=0.74％-1.02％) in females (x2=1.232,P＞0.05).Those aged 40-54 years old had the highest adjusted prevalence of depressive episodes(1.48％ (95％CI=0.77％-2.18％)).Conclusion The prevalence of depressive disorder in Mosuo nationality is in a low level,and the middle-age Mosuo people has the highest time-point prevalence.