Objective To assess clinical features and treatment of angiosarcoma.Methods A retrospective study was carried out among seven patients hospitalized for angiosarcoma in the Department of Plastic Surgery,Zhongshan Hospital of Fudan University from January 2004 to March 2012.Clinical behaviors,therapeutic strategies and outcomes of angiosarcoma were analyzed in these patients.Results Of the seven patients,four were male,and three were female,with a median age of 67 years (range,37-77 years).Clinical presentations were various,including irregular ulcerous nodular masses in four patients,localized ulcer in one patient,and irregular erythematous nodules in two patients.All the patients were treated surgically with or without postoperative adjuvant therapy.Pathological examination revealed various degrees of differentiation and atypia of tumor cells,as well as obvious proliferation of endothelial cells,and all of these patients were diagnosed as angiosarcoma.Immunohistochemical analysis revealed a positive staining for CD31 and CD34.After surgical treatment,angiosarcoma recurred in four patients with the median time to the first recurrence being 3.5 months (range,1-6 months),cerebral metastasis occurred in one patient 5 months later,and two patients died.Conclusions Angiosarcoma is a rare and heterogeneous sarcoma with diverse clinical presentations.Local wide resection is the cornerstone of angiosarcoma treatment,and adjuvant therapy may improve its prognosis.

Objective To introduce our experience about the breast reconstruction using latissimus dorsi (LD) flap combined with breast implant.The details of the operative method were prescribed.Methods During the LD mycutaneous breast reconstruction,the insertion of LD was cut off and rotated to fulfil ipsilateral axillary fossa.The breast reconstruction was performed using LD and breast implant.Results 237 cases of breast reconstruction were performed from 1998 to 2017.The axillary contour deformity was successfully restored.The results were satisfied and stable during the follow-up.Conclusions Using proximal LD flap to repair axillary fossa deformity is a safe,effective and easy operating method in LD and implant flap breast reconstruction.