No abstract available.
Breast* ; Osteosarcoma*

The purpose of this study was to provide fundamental data to propose further directions of education on rehabilitation nursing by investigating the adequacy of the educational contents of rehabilitation nursing. This study was a descriptive survey study. The data collected at 25 universities and 24 junior colleges through questionnaires to answer the research questions from August 10 to September 30, 2000. The questionnaire was consisted of 24 items. The contents of rehabilitation nursing education were developed by consulting with the rehabilitation nursing professionals. The results are as follows Rehabilitation nursing was taught as an independent class in 15 universities and 9 junior colleges. Most professors majoring in adult nursing(66.8%) were in charge of teaching the courses. For the adequacy of the teaching contents of rehabilitation nursing, conceptual bases for rehabilitation was the highest score(4.0), and interdisciplinary rehabilitation team, activities of daily living, clients of rehabilitation, nursing process in rehabilitation nursing, functional evaluation, movement and mobility, physical therapy, occupational therapy, sensation and perception, communication/language, eating and swallowing, bladder elimination, community based rehabilitation nursing, sleep, rest &, fatigue, bowel elimination., historical perspectives of rehabilitation nursing, sexuality, pulmonary rehabilitation, pain, cardiac rehabilitation, skin integrity, family care was ordered.
Activities of Daily Living ; Adult ; Deglutition ; Eating ; Education ; Fatigue ; Humans ; Nursing Process ; Occupational Therapy ; Surveys and Questionnaires ; Rehabilitation Nursing* ; Rehabilitation* ; Sensation ; Sexuality ; Skin ; Urinary Bladder

PURPOSE: Tamoxifen has been well known as an effective anti-tumor agent against breast cancer. The important role of bcl-2 and p53 proteins in tamoxifen-induced apoptosis of breast cancer cells has been suggested. However, the paradoxical fact that bcl-2 over-expression is assdegrees Ciated with better prognosis in clinic has not yet been clearly explained. To investigate this paradox, we analyzed the effect and dynamics of bcl-2 and p53 on the apoptosis after treatment of breast cancer cells with tamoxifen. MATERIALS AND METHODS: The human breast cancer cell lines MCF-7 and MB MDA-468 were treated with 17-betaestradiol (E2) and tamoxifen. RESULTS: Following tamoxifen treatment, MCF-7 cells underwent apoptosis accompanied by reduced bcl-2 expression. E2 pre-treatment led to the inhibition of tamoxifen-mediated apoptosis and bcl-2 down-regulation. When MB MDA-468 cells were treated with E2 or tamoxifen, bcl-2 and p53 protein expression did not change and apoptosis did not develop. CONCLUSION: We observed that the down-regulation of bcl-2 by tamoxifen treatment can facilitate the apoptosis of breast cancer cells without p53 mutations. This finding was consistent with clinical experiences in which bcl-2 positive tumors were assdegrees Ciated with more indolent phenotypes in breast cancer.
Apoptosis* ; Breast Neoplasms* ; Breast* ; Cell Line* ; Down-Regulation ; Humans* ; MCF-7 Cells ; Phenotype ; Prognosis ; Tamoxifen

This study was conducted to investigate the nursing diagnosis applying to rehabilitation unit. The subject of this was consisted of 101 nurses who have been working over 1 year in rehabilitation unit. The clssification of nursing diag-nosis used NANDA's system and analysis of the validity was based on Fehring's model. In summury of this study, some dirrerences were found in related factors in nursing diagnosis between rehabilitation and general unit. Major re-lated factors of nursing diagnosis were physical factors associated with neuromuscular disorder. Valid related factors in altered nutrition: more than body requirements was not found for re-habitation unit. It is helpful for the nurses who work at re-habilitation unit to apply the nursing diagnosis validated in this study. This finding can be used as the database for accomplished nursing diag-nosis appropriate for improving the rehabilitation nursing practice.
Nursing Diagnosis* ; Nursing* ; Rehabilitation Nursing* ; Rehabilitation*

The development of standards and guidelines of rehabilitation nursing has been the major concerns for providing better nursing to the rehabilitation clients. As the patients with stroke and spinal cord injuries are the most prevalent physical disabilities in Korea, this study focussed on the nursing diagnoses of these two groups of patients. In order to identify the nursing diagnoses frequently used in their practice for the patients with stroke and spinal cord injuries, a survey was done with the questionnaire form developed by the research team. The surveyee were the staff nurses working at rehabilitation wards more than 2 years from 8 general hospitals in Korea. They identified and set the priorities of 13 nursing diagnoses from 79 stroke patients and 10 nursing diagnoses from 35 patients with spinal cord injuries during the periods from March 1 to June 2, 1999. The identified nursing diagnoses for the stroke patients are impaired physical immobility, sensory-perceptual alterations, activity intolerance, self -care deficit, altered defecation, altered urination, risk for injury, unilateral neglect, impaired skin integrity, altered thought processes, pain, altered health maintenance, dysreflexia. The identified nursing diagnoses for spinal cord injuries are altered urination, altered defecation, impaired skin integrity, pain, risk for injury, reflex incontinence, impaired physical immobility, self-care deficit, activity intolerance, knowledge deficit.
Defecation ; Diagnosis* ; Hospitals, General ; Humans ; Korea* ; Nursing ; Nursing Diagnosis ; Surveys and Questionnaires ; Reflex ; Rehabilitation Nursing* ; Rehabilitation* ; Self Care ; Skin ; Spinal Cord Injuries* ; Spinal Cord* ; Stroke* ; Urination

Purpose: The purpose of this study was to translate Duke University Religion Index (DUREL) and the Daily Spiritual Experience Scale (DSES) into Korean and test the validity and reliability of the instruments. Methods: Korean version of DUREL and DSES were translated and back-translated by 6 bilingual experts and group discussions. Data analyses were performed using SPSS 26.0 and AMOS 22.0. Both exploratory and confirmatory factor analyses were conducted with two data sets of secondary analysis study to examine the factor structure and construct validity. Correlations with other variables were used to test validity and reliability. Results: For K-DUREL, the final evaluation yielded two factors with 5 items: intrinsic religiosity and institutional religious activity. K-DSES had two factors with 16 items: transpersonal spiritual experience, and interpersonal & environmental spiritual experience. Cronbach’s ⍺ of K-DUREL and K-DSES were .67 and .96, respectively. Both instruments showed good reliability and validity for the translated Korean versions. Conclusion Applying K-DUREL and K-DSES in theory-based research may contribute to knowledge about the religious activity and spiritual experiences in the health and well-being of a Korean. Also, two instruments have the potential to measure changes in religion and spirituality after spiritual or holistic nursing interventions.

Purpose: The purpose of this study was to translate Duke University Religion Index (DUREL) and the Daily Spiritual Experience Scale (DSES) into Korean and test the validity and reliability of the instruments. Methods: Korean version of DUREL and DSES were translated and back-translated by 6 bilingual experts and group discussions. Data analyses were performed using SPSS 26.0 and AMOS 22.0. Both exploratory and confirmatory factor analyses were conducted with two data sets of secondary analysis study to examine the factor structure and construct validity. Correlations with other variables were used to test validity and reliability. Results: For K-DUREL, the final evaluation yielded two factors with 5 items: intrinsic religiosity and institutional religious activity. K-DSES had two factors with 16 items: transpersonal spiritual experience, and interpersonal & environmental spiritual experience. Cronbach’s ⍺ of K-DUREL and K-DSES were .67 and .96, respectively. Both instruments showed good reliability and validity for the translated Korean versions. Conclusion Applying K-DUREL and K-DSES in theory-based research may contribute to knowledge about the religious activity and spiritual experiences in the health and well-being of a Korean. Also, two instruments have the potential to measure changes in religion and spirituality after spiritual or holistic nursing interventions.

Purpose: The study aimed to translate the Couple Satisfaction Index (CSI 32) into Korean, to evaluate the reliability and validity of CSI 32 and short-form (CSI 16, 4) in the Korean context, and to determine a cut-off score for Korean couples. Methods: Korean Versions of the Couple Satisfaction Index (K-CSI) 32 was translated, back-translated, and reviewed by five bilingual experts. Confirmatory factor analysis (CFA) was conducted with data from a sample of 218 couples (N = 436) to test construct validity. Validity and reliability were evaluated. The receiver’s operating characteristics curve analysis was used to obtain the cut-off score. Results: The construct validities of K-CSI 32, 16, and 4 were verified using one-factor structures. The results of CFA showed a slightly better fit for K-CSI 16 and 4 than for K-CSI 32. Convergent validity was supported by significant positive correlations of K-CSI with Kansas Marital Satisfaction Scale, Dyadic Adjustment Scale, and Family Relationship Assessment Scale. Moreover, the significant differences in K-CSI between normal and depressive group demonstrated known-group validity. Cut-off scores of 105.5 on K-CSI 32, 50.25 on K-CSI 16, and 13.25 on K-CSI 4 were validated to identify distressed couple relationships. Conclusion For clinical practice, the reliable and valid K-CSI 32 has the potential to measure changes in couple satisfaction after couple therapy or interventions. Applying K-CSI 32 may facilitate research on couple and family relationships in nursing and contribute to the discussion on the role of couple satisfaction in mental health.

Differential diagnosis between autoimmune pancreatitis (AIP) and pancreatic cancer is often difficult due to similar clinical manifestations and radiological findings. Serum immunoglobulin G4 (IgG4) is a marker to differentiate AIP from pancreatic cancer. Although serum IgG4 can be elevated in 10% of patients with pancreatic cancer, most of serum IgG4 elevation in pancreatic cancer is limited within two times of upper normal limit. Herein, we report a case of pancreatic cancer with markedly elevated serum IgG4 over six times of upper normal limit that needed steroid trial to differentiate from AIP.
Diagnosis, Differential ; Humans ; Immunoglobulin G ; Immunoglobulins* ; Pancreatic Neoplasms* ; Pancreatitis

PURPOSE: This study was conducted to describe qualitatively the entities of nurse's experiences in general hospitals and to suggest basic data guiding research on developing Standards of clinical nursing practice in Korea. METHOD: Fourteen nurses working at general hospitals with over 300 beds in Seoul were interviewed in-depth until saturation using tape-recorders and transcription. RESULT: The central theme of clinical nursing practice experienced by subjects was "being with clients" that means accepting client's personal character, solving client's needs and providing client-centered nursing. A also "being with clients" was felt to be the responsibility of nurses which was learned from their nursing schools. The nursing strategies performed in order to be with patients were proving skillful nursing techniques, accepting, educating, emotional support, advocating, and self-reflecting, the subjects experienced somewhat problematic affects such as difficulties in interpersonal relationship, work overload, negative image of nursing, deficit of self-confidence for nursing actions, poor working conditions, and unfair treatment. Nurses at the hospital practiced with pride when they felt that they were accepted by clients. CONCLUSION: Further research is needed to analysis problems in clinical practice and the comparison of nurses' experiences of clinical practice, with nurses' experiences in various settings.
Hospitals, General ; Humans ; Korea ; Nursing ; Schools, Nursing ; Seoul