ObjectiveTo investigate the test-retest reliability about the lower extremities static joint position sense which was tested with the Tetrax balance-test-training system, and the dynamic joint position sense which was tested with the Functional Squat System; and to investigate the relationship between the static and the dynamic joint position sense of lower extremities of the patients with knee osteoarthritis. Methods30 patients with knee osteoarthritis were tested with the lower extremities static and dynamic joint position sense twice within 7 d with the Tetrax balance-test-training system and the Functional Squat System. ResultsThe intraclass correlation coefficient (ICC) of the sum of the coefficient of medium-to-high-frequency in postural sway was 0.95 (P<0.001). The ICC of the reposition accuracy error mean of the unaffected/mild or affected/severe extremity were respectively 0.59 and 0.60 (P<0.001). The Pearson correlation coefficients of the sum of the coefficient of medium-to-high-frequency in postural sway and the reposition accuracy error mean of the unaffected/mild or affected/severe extremity were respectively 0.40 and 0.54 (P<0.05). ConclusionThe lower extremities static joint position sense test of the Tetrax balance-test-training system is well reliable, as well as the dynamic joint position sense of the Functional Squat System. They can be used together to evaluate the lower extremities proprioception in the patients with knee osteoarthritis.

Falls occurring in populations of elder people are prevalent as dangerous public health events that can result in the considerable institutionalization or even postfall morbidity and mortality. The prevention and intervention of falls in the elderly are the important fields of geriatric rehabilitation medicine. This paper reviewed the literature related to the falls in the elderly, involving the conception, incidence, evaluation and identification of risk factors, and multiple-risk-factor intervention strategy, and indicates the further research direction.

Objective To further improve the awareness of the clinical feature of acute fibrinous and organizing pneumonia (AFOP).Methods One case of AFOP treated in our department was described in details.The relevant cases were searched in Wanfang database using key words acute fibrinous and organizing pneumonia [in Chinese].Results Four reports containing 9 cases were identified from published literature.A total of 10 cases (including this one) were analyzed.The patients included 7 males and 3 females (43 to 78 years of age).Eight patients presented with cough.Chest tightness and dyspnea were reported in 8 cases,and fever in 9 cases.Velcro crackles were heard in 4 patients.Laboratory tests showed WBC increased in 2 cases,increased neutrophil count in 6 cases,elevated C-reactive protein in 9 cases,and faster erythrocyte sedimentation rate in 8 cases.The partial oxygen pressure (PO2) ranged from 54 mmHg to 69 mmHg.Chest CT scan showed unilateral lesions in 3 cases and bilateral lesions in 7 cases initially.The main CT findings were patchy,consolidation and ground-glass opacities,sometimes associated with air bronchogram.The diagnosis was confirmed by lung biopsy in all the 10 cases.Bronchoscopy biopsy was conducted in 6 cases,and percutaneous lung biopsy in 3 cases.One patient received both bronchoscopy biopsy and percutaneous lung biopsy.Methylprednisolone was used in all cases.No patient received mechanical ventilation.One patient died.Conclusions AFOP is a new type of interstitial lung disease,the etiology of which is unknown.AFOP often occurs in middle-and old-aged patients.AFOP is easily misdiagnosed due to its unspecific clinical manifestations,which are similar to common pneumonia.The confirmation of AFOP diagnosis depends on pathological biopsy.Corticosteroids treatment is appropriate,but the dosage,duration,and long term effect of corticosteroids are not established.

Objective To assess the test-retest reliability of Tetrax posturographic balance assessment system in determining the balance function in elderly individuals. Methods 22 elderly subjects (66~84 years old) were measured with the stability index (ST), the spectrum analysis of postural sway and the weight distribution harmony between two foots or heels and toe parts in standing on solid surface with eyes open using Tetrax balance system. All tests were repeated 1 week after the initial test and each subject underwent the test under the same instructions and conditions. The intraclass correlation coefficients (ICC) were used to determine the test-retest reliability. Results ICC of all balance functional parameters ranged from 0.797~0.882 (P<0.01). Conclusion The posturographic balance assessment system has good test-retest reliability for determining the balance function in elderly people.

ObjectiveTo determine the static equilibrium of elderly individuals over the age of 60 and the correlation to the age. Methods142 elderly subjects (60～95 years old) were divided into 7 groups: 60～65 years old group, 66～70 years old group, 71～75 years old group, 76～80 years old group, 81～85 years old group, 86～90 years group, and >90 years old group, 24 cases 18～30 years old as the control. The static equilibrium was examined by measuring the stability index （ST） and the spectrum analysis of postural sway under following 4 conditions: standing on solid surface with eyes open （NO），standing on solid surface with eyes closed （NC）， standing on pillows with eyes open （PO）， and standing on pillows with eyes closed （PC） using Tetrax Balance System. ResultsThe ST and the intensity of postural sway increased in the elderly group compared with the control group. NO: there were significant differences (P<0.01) in ST, F1, F4, F6, F8 among the 81～85 years group, 86～90 years old group, >90 years old group and the control group. NC: there were significant differences (P<0.01) in ST, F1, F4 among all the elderly groups and the control group, and in F6, F8 among the >66 years groups and the control group（P<0.05）. PO: there were significant differences (P<0.01) in ST, F4, F6 among the >66 years old groups and the control group, and in F1, F8 among the >71 years old groups and the control group（P<0.05）. PC: there were significant differences (P<0.01) in ST, F4 among all the elderly groups and the control group, in F6 among the >66 years groups and the control group, in F8 among the >76 years old groups and the control group, and in F1 among the >80 years old groups and the control group（P<0.05）. The ST distributed as NOP<0.01）. There were similar changes in the intensity of postural sway of F1, F4, F6, F8 bands. ConclusionThere is the significant decline of the static equilibrium in the subjects aged 80 or over and no significant decline of the static equilibrium in the subjects aged 60～80 whose compensation in the static balance may decrease.

Objective To study characteristics and current situation of physically restrains (PR) patients in ICU in third-level hospitals.Methods The physical restrains of ICU patients from January to June 2017 in a third-level hospital in Jiangsu Province was prospectively analyzed.Results The usage rate of physical restraint was 69.4％,and the usage number of restraint was 19 ～ 37.5,with median number of 19 times.The proportion of total restraints to total hospitalized restraint was 79.4％.The PR tools and restraint locations were single.The restraint complication occurred 78 times,with the complication rate of 45.7％ (59/129).Conclusion ICU patients have higher body constraint usage,longer constraint time,higher incidence of complications.So the nurses need to strengthen PR-related education and training to reduce the PR usage and complications.

Objective To study characteristics and current situation of physically restrains (PR) patients in ICU in third-level hospitals.Methods The physical restrains of ICU patients from January to June 2017 in a third-level hospital in Jiangsu Province was prospectively analyzed.Results The usage rate of physical restraint was 69.4％,and the usage number of restraint was 19 ～ 37.5,with median number of 19 times.The proportion of total restraints to total hospitalized restraint was 79.4％.The PR tools and restraint locations were single.The restraint complication occurred 78 times,with the complication rate of 45.7％ (59/129).Conclusion ICU patients have higher body constraint usage,longer constraint time,higher incidence of complications.So the nurses need to strengthen PR-related education and training to reduce the PR usage and complications.

At present, there are few reports on the surgical treatment of female urethral mucosal prolapse in China, and the selection of surgical methods and surgical plans need to be optimized. In this study, we retrospectively analyzed the data of 43 female patients with urethral mucosal prolapse treated by " three-way circumcision" in our hospital. The length of hospital stay was (10.02±2.23) days, the postoperative indwelling catheter was (6.42±0.88) days, and the postoperative hospital stay was (7.28±1.26) days. Only 2 patients had a prolonged hospital stay due to urinary tract infection after surgery. This surgical procedure has a short operation time, low surgical difficulty, few postoperative complications, low postoperative recurrence rate, and is generally simple, safe and effective.

AIMTo determine the effect of piperazinyl estrone, a new estrogen derivative, on bone turnover, bone mass and uteri in ovariectomized rats.

METHODSFemale Sprague-Dawley rats were ovariectomized (OVX) or sham operated (sham) at the age of 3 months and treated with estrone (E) at 0.75 mg.kg-1.d-1, or with piperazinyl estrone (P-E) at 1 or 10 mg.kg-1.d-1, orally, for 3 months. At the time of death, the uterine weight was measured. Bone histomorphometric analysis of proximal tibial metaphyses (PTM) was performed in undecalcified sections.

RESULTSBone histomorphometric data showed that the percent trabecular area (% Tb.Ar) of OVX rats with bone high turnover was significantly decreased. The uteri were atrophied. The percent trabecular area (% Tb.Ar) of estrone treated group was increased in decreasing bone turnover manner. But the size and weight of uteri in this group were increased vs OVX group. The bone loss induced by OVX was preserved by P-E treatment, but the mechanism of maintaining bone is different from that of E-treated rats. P-E treatment in low dose did not decrease any bone formation indices, such as percent labeling perimeter, bone formation rate per bone volume (BFR/BV), except bone mineral apposition rate (MAR) compared with E-treated group, and maintained them at OVX level. The uteri were found to be in atrophy compared with the match dose (0.75 mg) of E-treated OVX rats. But rats treated with high dose of P-E showed the same change like E-treated group.

CONCLUSIONThe finding of this study shows that lower dosage of piperazinyl estrone has effect on preventing the bone losses in OVX rats, while the bone formation and the uterus are not affected, thus supporting the hypothesis that piperazinyl estrone has the potential to prevent postmenopausal bone loss in women with less side effects.

Animals ; Atrophy ; prevention & control ; Bone Density ; Estradiol Congeners ; pharmacology ; therapeutic use ; Estrone ; analogs & derivatives ; pharmacology ; therapeutic use ; Female ; Organ Size ; drug effects ; Osteogenesis ; drug effects ; Osteoporosis ; prevention & control ; Ovariectomy ; Rats ; Rats, Sprague-Dawley ; Uterus ; pathology

Aged ; Endoscopy ; methods ; Female ; Humans ; Laparoscopy ; Lymph Node Excision ; methods ; Video-Assisted Surgery ; methods ; Vulvar Neoplasms ; surgery