In recent years,more and more experts and scholars study enhancer of zeste homolog 2 (EZH2) and the relationship of the overexpression of EZH2 gene with the occurrence,development,metastasis,and prognosis of tumor,to explore the early diagnosis of cancer,monitoring metastasis and judging the prognosis to provide the new ideas and the methods,to provide the reference for the basic and clinical research.

Deep vein thrombosis is one of venous thromboembolism clinical manifestations,but also a serious,potentially dangerous disease.Thrombosis can occur in various parts of the body veins,and deep venous thrombosis is the most common.Even though most patients with DVT have no clinical symptoms or with mild symptoms,but failure to timely appropriate treatment is easy to progress to post thrombotic syndrome,shares bruises,stock white swollen,which can occur in severe pulmonary embolism and cause death.Although clinically in a variety of measures to prevent DVT formation,including physical prevention and drug prevention,but the incidence of deep vein thrombosis remains high,9-36％ after total hip arthroplasty,and 52％ after total knee arthroplasty.DVT is a disease combined with genetic and non-genetic factors,60％ DVT patients have hereditary risk factors.Currently genetic factors on the formation of DVT study find that clotting factor Ⅺ gene polymorphisms is associated with DVT.Coagulation factor Ⅺ (F Ⅺ) is a serine protease synthesized by the liver and plays an important role in the coagulation cascade process such as maintain the amplification process and the intrinsic pathway.Research on correlation between single nucleotide polymorphisms (SNPs) of F Ⅺ locus rs2289252 and rs2036914 and deep vein thrombosis has become popular.This paper reviews the discovery of coagulation F Ⅺ single nucleotide polymorphism associated with DVT,the degree of association between coagulation F Ⅺ single nucleotide polymorphism and the formation of DVT,risk allele on the clotting F Ⅺ single nucleotide polymorphism,clinical trials of coagulation F Ⅺ and the formation of DVT,coagulation F Ⅺ single nucleotide polymorphisms interact with other genetic polymorphisms,etc.Although the single nucleotide polymorphism in DVT formation mechanism is still vague,we believe that further study of single nucleotide polymorphisms associated with DVT will provide new approaches to prevention and treatment of DVT.

It is high time to regulate the Chinese medical ethics review system and construct a supervision system of medical ethics review.According to the guideline of WHO,models of supervision system of medical ethic review in certain developed countries,and national conditions,this paper proposes several countermeasures including perfecting related legal system,constructing certification system of ethics review committee,and formulating integrated contents and procedure of supervision.

Moral emotion education of medical students should begin with arousing human nature of students and making them to have the sense of consciousness to patients, which takes sympathy as the core. However, when faced with the increase of doctor-patient contradiction, students are easy to suspect the general sense. So students should be guided to understand the necessity of moral emotion in professional activity of doctors, and thus to adhere to treat patients with emotion due to responsibility. On this basis, through combining the education of having emo-tion to patient with working reasonably, medical students will gradually take treating patients with emotion as their own compulsory emotion, and to realize the transformation from human nature to medicine nature.

Consumer Product Safety ; Drinking Water ; standards ; Equipment Safety ; Food Safety ; Public Health ; instrumentation ; methods ; Safety Management ; Water Supply

Objective: To guarantee the normal treatment of hospital, increasing the diagnosis rate and cure rate and efficiency of health care. Methods: Strengthening the maintenance and management of medical equipment by design computer information management system which can be very useful for daily maintenance management. Results: It is used to manage medical equipment maintenance, such as equipment basic information registration, equipment maintenance, equipment inspection, repair equipment archives management, equipment scrapped etc. Conclusion: The system improves the efficiency of medical equipment maintenance, and increases the benefit of hospital.

Asthma is a chronic airway inflammatory disease,which is caused by both genetic and environmental factors.For one thing, asthma is associated with genetic factors;for another thing, many exogenous triggering factors,such as diatery intake, smoke exposure and air pollution can impact on the development of asthma.Recently,many studies have showed that epigenetic changes which are influenced by the both factors play an important role in the pathophysiology of asthma.This article reviews the update advances about the epigenetic regulation and epigenetic therapy in asthma.

Environmental Monitoring ; methods ; Environmental Pollutants ; analysis ; Microchip Analytical Procedures

Intestinal mucosal barrier has the function to isolate intestinal contents and internal environment,prevent foreign antigens and pathogens invading to lamina propria mueosae and can maintain organic homeostasis and normal activities.Impairment of the intestinal barrier is a key event in various gastrointestinal diseases.Probiotics are live microorganisms which ingested and reach the intestines in sufficient numbers to confer benefit to the host.It can improve or prevent many gastrointestinal diseases.The main reason is probiotics can maintain intestinal barrier function in various paths.This paper reviews its mechanisms of action.

This article is trying to find out the historical and realistic reasons of the restriction of the process of modernization of traditional Chinese medicine (TCM) from the history of TCM theory and practice of TCM institutional setup and related policies and many other aspects.Then it points out that the TCM in the background of the development of science and technology today is already has the necessary conditions of modernization,but the process can not be succeed overnight,it ought to be a systematic engineering.