In this study, using PC server. we developed large scale hospital order communication system which is classified into 3 categories of business: clinical business, clinical support business, patient management business. In all the programs to build OCS, the user's convenience was considered as a top priority. which was built in the environment of 'window'; in this, the tool to develop the programs was a 'Visual Basic' In consideration of the aspect of operation. the programs were consolidated into one kind. The database was built into a relation-type database. MS/SQL which is easily interchangeable or portable personal database: and data exchange with real users was also made casy. Since all kinds of business concerned built in open system, this hospital information system can actively cope with any of environmental changes, and since this system was developed by manpower within an organization of a hospital. the system can flexibly and efficiently correspond to its operation.
Commerce ; Hospital Information Systems ; Humans

OBJECTIVE: The development of information communication technology (ICT) and the demand for managing the healthy lives of individuals are accelerating the informatization of the health and medical field. Considering this environment and the needs of the individual, this paper has designed and developed a web and mobile storage device-based personal health record (PHR) system that individuals can manage by themselves anywhere, anytime, whether on-line or off-line. Based on the experience of implementing the system, its development method, results, and relevant technical issues are described. SYSTEM DESIGN AND DESCRIPTION: This system is implemented to manage PHR, including vital signs and ingested/consumed calories for a lifetime by connecting a PHR-integrated web server to each hospital's information system, and the PHR programs installed in the individual's PC or USB flash memory drive. To achieve this, an interface module, web server system, and PHR viewer program for individuals are developed. RESULTS: When it is off-line, the PHR program is operated to inquire the data saved in the DB, and the self-measured information can be inputted. When it is on-line, it calls the web service function to inquire the medical information, including hospital visit history, prescription history, diagnosis result, image inspection result and medical treatment result. CONCLUSION: This system connects home and mobile healthcare to hospitals but minimizes information leakage because the data is not accumulated. By loading a plug & play, PHR viewer to an easy-to-carry mobile storage device, the systems supports a sustainable health management.
Access to Information ; Delivery of Health Care ; Health Records, Personal ; Humans ; Information Systems ; Medical Records ; Memory ; Prescriptions ; Vital Signs

In this study, using the HL7 protocol, we developed patient management system gateway which is composed of 2 parts; message transferring-receiving and sentcncc generating-parsing part. To make the gateway more transplantable, it was developed on the PC operated with Windows OS. To make the gateway more productive, it was developed with Visual Basic 6.0. The database was built into MS SQL. Server which is most optimized on MS Windows NT system environment. This gateway system has the advantage of easy data-exchange capability between the patient management systems of medical facility and the messages transferred can he managed systematically and he transplanted easily into PC base hospital information system.
Hospital Information Systems ; Humans

In this study, we developed an order communication system (OCS) gateway, which observe the protocol of HL7 standard and is operated on PC. In the aspect of architecture, the OCS gateway consists of three modules, which are message transmission/reception, data processing, and security. In the aspect of user interface, the OCS gateway consists of two main screens, which are order data management and message transmission. The main function of the OCS gateway is to convert the order records such as pharmacy, observation and diagnostic study, radiology, other diagnostic study, and treatment to a message, which observe the protocol that presented by HL7 standard, and transmit the message to other OCS gateway. To enforce the security of this gateway, we applied a hybrid security method using both Rivest-Shamir-Adleman (RSA) and Data Encryption Standard (DES). With the developed OCS gateway, different OCS systems in the inside and outside of the country can exchange their order data effectively and safely. Because it is developed for PC base Windows operating system, this gateway is more transplantable to the existing hospital information system (HIS) which is constructed on PC.
Hospital Information Systems ; Pharmacy

The purpose of this study was to delineate the various factors that affect the growth characteristics of human cancer xenografts in nude mice and to reveal the relationship between the growth characteristics and radiosensitivity. We retrospectively analyzed 390 xenografts comprising nine different human cancer lines grown in nude mice used in our institute between 2009 and 2015. Tumor growth rate (TGR) was calculated using exponential growth equations. The relationship between the TGR of xenografts and the proliferation of the cells in vitro was examined. Additionally, we examined the correlations between the surviving fractions of cells after 2 Gy irradiation in vitro and the response of the xenograft to radiation. The TGR of xenografts was positively related to the proliferation of the cells in vitro (r(P)=0.9714, p<0.0001), whereas it was independent of the histological type of the xenografts. Radiation-induced suppression of the growth rate (T/C%) of xenografts was positively related to the radiosensitivity of the cells in vitro (SF₂; r(P)=0.8684, p=0.0284) and TGR (r(P)=0.7623, p=0.0780). The proliferation of human cancer cells in vitro and the growth rate of xenografts were positively related. The radiosensitivity of cancer cells, as judged from the SF₂ values in vitro, and the radiation-induced suppression of xenograft growth were positively related. In conclusion, the growth rate of human xenografts was independent of histological type and origin of the cancer cells, and was positively related to the proliferation of the cancer cells in vitro.
Animals ; Heterografts* ; Humans* ; In Vitro Techniques ; Kinetics* ; Mice ; Mice, Nude ; Radiation Tolerance* ; Retrospective Studies*