1.Expression of CD30 and CD30 - mediated Enhancement of ICAM - 1 Expression on Mouse Splenic B Lymphocytes.
Korean Journal of Immunology 2000;22(4):287-298
No abstract available.
Animals
;
B-Lymphocytes*
;
Mice*
3.Efficacy of a 20% Aluminum Chloride in Alcohol Solution in the Treatment of Hyperhidrosis: A Study Using a Hydrometer.
Nam Joon CHO ; Seung Hun LEE ; Doo Yun LEE
Annals of Dermatology 1998;10(1):20-24
BACKGROUND: Excessive sweating, especially of the palms, soles and axillae, is a socially and an occupationally distressing, and sometimes disabling condition. A variety of treatment methods are used to reduce profuse sweating including topical agents, iontophoresis and symphatectomy. OBJECTIVE: We investigated whether a 20% aluminum chloride solution is efficient in the treatment of axillary and palmoplantar hyperhidrosis using a skin surface hydrometer. METHODS: We treated 31 patients (7; male, 24; female) by Drysol once a day at bedtime for four weeks. We had measured the conductances on the stratum corneum of the palms, soles and axillae using a skin surface hydrometer before and after treatment every week for four week RESULTS: There was a reduction of conductances after the treatment by Drysol (p<0.05). The reduction of conductances was continued for four weeks (p<0.05). CONCLUSION: Drysol is an efficient, safe, and simple method for initial treatment of the primary hyperhidrosis.
Aluminum*
;
Axilla
;
Humans
;
Hyperhidrosis*
;
Iontophoresis
;
Male
;
Methods
;
Occupations
;
Skin
;
Sweat
;
Sweating
4.The Meniscal Cyst of the Knee
Duck Yun CHO ; Jai Gon SEO ; Sung Nam BAEK
The Journal of the Korean Orthopaedic Association 1990;25(5):1414-1421
Cysts of the meniscus are rare lesion of the knee. They may present as a local tumor or mimic signs of an internal derangement of the knee. So it is difficult to diagnose and apt to overlook in physical examination. Also they almost always have combined pathology of the involved meniscus, such as, meniscal tear or discoid meniscus. The pathologic basis of the meniscal cyst is controversial, but rece 2. Most of the patients had tear of the involved meniscus, but the patients with discoid meniscus did not have gross tears or previous trauma history. nt works suggest the etiology is infiltration of joint fluid through micro and macro tears in the meniscus. In the past, complete excision of the meniscus as well as cyst was thought to be the treatment of choice to prevent recurrences. But nowadays, the trend is changed as preserving the involved meniscus, when no tear of the meniscus is found to prevent enevitable degenerative changes after total meniscectomy. We experienced 6 cases of meniscal cyst during recent 2 years and obtained following results. 1. Precise joint line evaluation is much more important in the diagnosis of the meniscal cyst before making special study. 2. Most of the patients had tears of the involved meniscus, but the patients with discoid meniscus did not have gross tears or previous trauma history. 3. When the cyst is located anteriorly in the joint line, it is prominent in flexed position of the knee; and when located posteriorly, prominent in extended position of the knee. 4. Excision of the cyst and reattachment of the meniscus were thought to be good method when the cyst was located in the parameinscal area without gross tear of the involved meniscus.
Diagnosis
;
Humans
;
Joints
;
Knee
;
Methods
;
Pathology
;
Physical Examination
;
Recurrence
;
Tears
5.A Comparative Study of anterior Interbody Fusion with and without Anterior Instrumentation in Multi-level Tuberculosis of Thoraco-Lumbar Spine
Duck Yun CHO ; Eung Ha KIM ; Eun Sung KOH ; Kye Nam CHO
The Journal of the Korean Orthopaedic Association 1995;30(2):298-306
The anterior decompression and anterior interbody fusion have been the choice of surgical treatment for spinal tuberculosis since 1960. But, multi-level spinal tuberculosis involved more than three vertebrae resulted in large post-debridement defect and spinal instability. So, failure of the graft was very common & postoperative maintenance of the kyphotic angle correction was very difficult. In part of such cases as multi-level spinal tuberculosis, we performed supplementary anterior instrumentation in a single-stage procedure. The authors analyzed total 39 surgical cases of multi-level tuberculosis of the thoracolumbar spine from January 1985 to June 1992. The patients treated only with a strut graft were designated as group I(n=23) and the patients added by anterior instrumentation as group II(n=16). Mean age of 39 cases was 33.1 years, and mean follow-up period was 31.6 months. The purpose of this study was to compare the postoperative results of group I with those of group II by measuring the angular kyphosis on serial lateral roentgenograms, and to provide an aid in selecting method of surgery before treatment of multi-level spinal tuberculosis with high risk of progression of kyphosis. The results were as follows: 1. There were 16 cases of thoracolumbar, 14 cases of thoracic, 9 cases of lower lumbar lesions, and numbers of vertebrae involved were 4.2 in mean. 2. By standard Cobb lateral measurement, mean preoperative angle of segmental kyphosis was 32.5° in group I, and 45.1° in group II, and group II proved as more kyphotic. After operation, mean angle of segmental kyphosis was 24.7° in group I and 32.4° in group II. 3. On final F/U, mean angle of segmental kyphos was 32.7° in group I, and 37.3° in group II, and final loss of correction was 8.0° in group I, 4.9° in group II. 4. There were 8 patients(34.8%) of graft-related complications in Group I, and 2(12.5%) in group II. And graft failure in group I resulted in severe loss of correction of segmental kyphosis, but graft failure in group II did not, through graft protection by anterior instrumentation. 5. There were 3 patients(18.8%) of implant-related problems in group II; two during and one after union. In these former two cases, bony union was obtained without loss of correction by prolonged application of brace. No cases of group II was associated with persistence or recurrence of infection after instrumentation. In our opinion, anterior interbody fusion and combined anterior instrumentation can be effective and safe one of methods in surgical treatment for multi-level tuberculosis of the spine which has been considered as the most important determinant of the result by its extensive vertebral involvement with resulting large post-debridement defect to be struted.
Braces
;
Decompression
;
Follow-Up Studies
;
Humans
;
Kyphosis
;
Methods
;
Recurrence
;
Spine
;
Transplants
;
Tuberculosis
;
Tuberculosis, Spinal
6.Loss of the Sagittal angle in the Instrumented Segments after Pedicular Screw Fixation of the Degenerative Lumbar Diseases
Duck Yun CHO ; Eung Ha KIM ; Eun Sung KOH ; Kye Nam CHO
The Journal of the Korean Orthopaedic Association 1995;30(4):842-851
Vertebral stabilization using transpedicular screw fixation device is widely used in the surgical treatment of degenerative lumber diseases such as spinal stenosis, pseudospondylolisthesis, and spinal instability. The use of transpedicular screw fixation devices provides substantial advantages with regard to an increase of the rate of solid arthrodesis, early rehabilitation, short segment spinal fusion, and restoration of sagittal lumbar lordosis. The authors analyzed 11 patients showing definite postoperative loss of the lumbar sagittal lordosis in a total of 110 surgical cases of degenerative lumbar diseases who underwent segmental spinal fusion using transpedicular screws from January 1981 to December 1993. The purpose of this study was to analyze the causes of loss of lumbar sagittal lordosis in the instrumented segments and to present some precautions in transpedicular screw fixation for surgical patients with degenerative lumbar spines to maintain corrected lumbar sagittal lordosis. The results from this study were as follows: 1. By standard Cobb lateral measurements, eleven cases in a total of 110 patients showed definite loss of lumbar sagittal lordosis more than 4 degrees. 2. The period reflecting loss of lordosis was roughly within postoperative four months which were critical fusion time of the grafted bone mass, which lasted an average of 4.8 months in this study. 3. The implants led to loss of lordosis consisted of 6 cases in 53 Diapasons, 4 cases in 32 Wiltses, and a case in 15 Steffee plate systems. Diapason & Steffee plate systems were classified as a rigid type and Wiltse system as a flexible one. 4. The causes of postoperative loss of lordosis were recognized as 2 cases of screw toggling, 5 cases of screw-rod locking failure and 4 cases of rod bending. 5. The group resulted in more loss of lordosis in degrees was related to significant change between preoperative and postoperative lordosis, distraction of disc space during operation, extensive discectomy, and reduction of degenerative spondylolisthesis which were the cases of the anterior column deficiency.
Animals
;
Arthrodesis
;
Diskectomy
;
Humans
;
Lordosis
;
Rehabilitation
;
Spinal Fusion
;
Spinal Stenosis
;
Spine
;
Spondylolisthesis
;
Transplants
7.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(I).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1991;23(2):218-229
No abstract available.
8.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(II).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1992;24(3):365-377
No abstract available.
9.Coronary and Left Ventricular Angiographic Findings of Acute Myocardial Infarction in Korean Adults.
Seung Yun CHO ; Won Heum SHIM ; Nam Sik CHUNG ; Woong Ku LEE ; Heung Jai CHOI
Korean Circulation Journal 1985;15(3):381-391
To delineate the coronary anatomy and the left ventricular function during early myocardial infarction, coronary arteriography and left ventriculography were performed prospectively in 28(34%) of 83 patients who were admitted to the coronary care unit at Severance Hospital from November 1983 to August 1984 within 30 days(median : 14 days;range : 4 hours to 30 days) after the onset of symptoms. The frequency of total occlusion of the infarct related artery was evaluated in the time course of infarction. To prove spontaneous recanalization, 3 patients who had total coronary occlusion underwent serial study within 11-20 days after the first study. We categorized the patients into two comparable groups according to the infarction site, coronary angiographic findings, and age. Comparison of clinical and angiographic findings between each group was made. The following results were obained. 1) There were 23 patients with transmural myocardial infarction(82.1%) and 5 with nontransmural infarction(17.9%). Among 23 patients with transmural infarction, 14 had anterior infarction(60.9%) and 9(39.1%) inferior infarction. 2) The mean age was 51.3 years(range : 31-79 years). The ratio of male to female was 3.7:1. 3) Fifteen patients(53.6%) had one-vessel disease, 10(35.7%) two-vessel disease and 2(7.1%) three-vessel disease, One patient(3.6%) had insignificant disease(less than 50% reduction in luminal diameter). Nontransmural infarction had a tendency to be associated with higher prevalence of multivessel disease than transmural infarction(80% vs 34.8%). 4) In 23 patients with transmural infarction, 12(52.2%) had complete occlusion and 11(47.8%) incomplete occlusion of the infarct related artery. Three patients(13.0%) had subtotal occlusion(90-99%) and 4(17.4%) had lesions of 70-89% luminal diameter narrowing. Three patients(13.0%) had 50-69% lesions and the remaining 1(4.4%) had insignificant obstructive lesions. 5) Of the 23 patients with transmural infarction, 12 were studied within 14 days and 11 in 15-30 days after the onset of symptoms. The frequency of total coronary occlusion was significantly higher in the patients studied within 14 days of symptom onset vs those studied in the 15-30 days period(83.3% vs 18.2%;p<0.001). Serial studies of 3 patients with total coronary occlusion at the initial study demonstrated occurrance of spontaneous recanalization in 2 patients. 6) The left ventricular-ejection fraction was higher in the patients with nontransmural infarction, inferior infarction, and incomplete coronary occlusion(65+/-14%, 58+/-16% and 57+/-17%) than that of the patients with transmural infarction, anterior infarction, and complete coronary occlusion(51+/-15%, 47+/-14% and 46+/-13, p<0.05). But there was no significant difference in left ventricular ejection fraction between the young(<45 year) and the old(> or =45 year) age groups. And also 0-1 vessel disease and 2-3 vessel disease groups did not show significant difference in ejection fraction. The degree of congestive heart failure was more severe in the patients with anterior infarction than in those with inferior infaction. multi-vessel disease group was significantly older than 0-1 vessel disease group(55+/-8 yrs vs 46+/-12 yrs, p<0.05), and the young age group had a tendency to be associated with higher prevalence of single vessel disease. 7) As for the complications of angiocardiography in this study, there was ventricular finbrillation in 2 patients(7.1%) without mortality. It is concluded that coronary arteriography can be safely performed within one month after acute myocardial infarction;high prevalence of one-vessel disease in acute myocardial infarction in the Korean adult patients admitted to a general hospital;lower incidence of total coronary occlusion in the late time course of infarction due to spontaneous recanalization;better left ventricular function in the patient groups with nontransmural infarction, inferior infarction and incomplete coronary occlusion.
Adult*
;
Angiocardiography
;
Angiography
;
Arteries
;
Coronary Care Units
;
Coronary Occlusion
;
Female
;
Heart Failure
;
Humans
;
Incidence
;
Infarction
;
Male
;
Mortality
;
Myocardial Infarction*
;
Phenobarbital
;
Prevalence
;
Prospective Studies
;
Stroke Volume
;
Ventricular Function, Left
10.2 Cases of Dual Left Anterior Descending Coronary Artery.
Kum Soo PARK ; Seung Yun CHO ; Yang Soo JANG ; Nam Sik CHUNG ; Woong Ku LEE
Korean Circulation Journal 1985;15(3):539-544
"Dual LAD" was defined as the early bifurcation of the proximal LAD into two vessels : a short LAD which remained in the anterior interventricular sulcus and does not reach the apex, and a long LAD which leaves the anterior interventricular sulcus only to return to the distal sulcus and continue to the apex. Recognition of "Dual LAD" is essential to prevent errors of interpretation of the coronary arteriogram and for planning of optimal surgical therapy. We report 2 cases of "Dual LAD" with the review of the literatures.
Coronary Vessels*