No abstract available.

The malignant fibrous histiocytoma (MFH) was first introduced in 1963 to refer to a group of soft-issue tumors characterized by a storiform or cartwheel-ike growth pattern and predominantly fibroblastic appearance. It was postulated that they were derived from histiocytes that could assume the appearance and function of fibroblasts. MFH has been recognized to be the most common sarcoma in the soft tissue of late adult life which involves the deep fascia or skeletal muscles of the extremities or retroperitoneum. It has been noted in other organs, however, it rarely arises in the liver. We report two cases of primary malignant fibrous histiocytoma of the liver histopathologically confirmed after surgical resection-storiform pleomorphic and myxoid subtypes in the 55 year old male and 49 year old female patients, respectively, and describes the clinical courses, characteristics and pathologic aspects with review of the related literatures.
Adult ; Extremities ; Fascia ; Female ; Fibroblasts ; Histiocytes ; Histiocytoma, Malignant Fibrous* ; Humans ; Liver* ; Male ; Middle Aged ; Muscle, Skeletal ; Sarcoma

Argon laser trabeculoplasty(ALT) is commonly used in the treatment of uncontrolled open angle glaucoma. The authors retrospectively reviewed the efficacy of ALT in 52 patients(57 eyes) with primary open angle glaucoma. The mean follow-up was 28 months(range 2-48 months). The decrease in intraocular pressure 10P) was 10.1 +/- 3.5 mmHg at 1 month, 8.2 +/- 2.8 mmHg at 1 year, 6.2 +/- 5.1 mmHg at 2 years and 51% at 3 years. Failure was most common in the first 6 months after treatment(29%) and thereafter failure occurred at a rate of 5% to 15% per year. The sex and age of patients had no significant effect on success rate. The success rate was high in the patients with baseline IOP of 26 to 30 mmHg. A mild iritis in all cases, transient rise in IOP, peripheral anterior synechia and microscopic hyphema were noted as early complications of ALT.
Argon* ; Follow-Up Studies ; Glaucoma, Open-Angle* ; Humans ; Hyphema ; Intraocular Pressure ; Iritis ; Retrospective Studies ; Trabeculectomy*

We had two cases of hepatitis developing after surgery. Case 1. A 47 year old male underwent surgery for amputation of the lower leg under enflurance anesthesia. Preoperative liver function test were slightly abnormal. On the 25th portoperative day, serum transaminases were elevated and the A/G ratio was reversed. On the 65th postoperative day, the liver function tests returned to near normal leve. Case 2. A 37 year old male underwent the first surgery for reduction of a pateliar fracture under spinal anesthesia. Preoperative serum transaminages were elevated and other laboratory findings at normal levels. On the 20th postoperative day serum transaminases were more elevated and on the 120th postoperative day, ti became normal again. This patient underwent the second surgery for removal of a K-wire under enflurane anesthesia and afterwards hepatitis recurred. On the 60th 2nd postoperative day LEFs became nearer to normal level and he was discharged in good health. Possible causes of the hepatitis in these cases were considered to be the preoperative liver disease, blood transfusion, the stress of the surgery and anesthesia.
Adult ; Amputation ; Anesthesia ; Anesthesia, Spinal ; Blood Transfusion ; Enflurane ; Hepatitis* ; Humans ; Leg ; Liver Diseases ; Liver Function Tests ; Male ; Middle Aged ; Transaminases

Infantile fibrosarcoma is a rare malignant soft tissue tumor occurring especially in newborn and young children under 2 years. We experienced three cases of infantile fibrosarcoma presenting in the neonatal period. Case 1 presented with a multiseptated cystic mass on his left thigh at birth that was diagnosed as lymphangioma. After picibanil injection, we noted the size of the mass doubled and a solid lesion was prominent in the magnetic resonance image. Case 2 was found to have a reddish mass on his lower back mimicking hemangioma. Over 2 weeks, the mass grew rapidly with internal hemorrhaging. Case 3 was noted to have an encircling mass around the splenic flexure, which developed into congenital bowel obstruction. All of the tumors were resected completely, but microscopic resection margin was not clear in two patients. The two patients received adjuvant chemotherapy and all patients are well without evidence of recurrence.
Chemotherapy, Adjuvant ; Child ; Colon, Transverse ; Fibrosarcoma ; Hemangioma ; Humans ; Infant, Newborn ; Lymphangioma ; Magnetic Resonance Spectroscopy ; Parturition ; Picibanil ; Recurrence ; Thigh

The increasing use of intravenous polyethylene catheters has led to a growing incidence of accidental catheter breakage and migration of fragments into the central vascular system usually in the inferior vena cave, the right atrium, of the pulmonary artery. The most common complications were formation of a thrombus in the area of the foreign body, infection with endocarditis, and perforation of the heart. And so obviously the polyethylene catheter must be removed. In 1967, Massumi and Ross et al have been successful in removing a catheter fragment from the right atrum percutaneously with a snare device. With some modification as suggested by Curry, method of retrieving fragments of polyethylene catheters from the heart without chest surgery utilize wire snares or endoscopic forceps. This report describe the technique and its use in successfully managing these complications in four consecutive cases.
Catheters* ; Endocarditis ; Foreign Bodies ; Heart Atria ; Heart* ; Incidence ; Polyethylene ; Pulmonary Artery ; SNARE Proteins ; Surgical Instruments ; Thorax ; Thrombosis

Toxoplasmosis is a ubiquitous protozoan infection caused by coccidian Toxoplasma gondii. In an immunocompetent host, the primary infection is generally oligosymptomatic and self-limiting. Fewer than 10% of infected subjects are symptomatic, with lymphadenopathy as the most frequent clinical finding. Here, two cases of Toxoplasmic lymphadenitis are reported for otolaryngologists to consider the clinical findings and natural history aspects of this infection.
Head* ; Lymphadenitis* ; Lymphatic Diseases ; Natural History ; Neck* ; Protozoan Infections ; Toxoplasma ; Toxoplasmosis

An unusual case of embryonal rhabdomyosarcoma of the bladder in a 77 year old man, who presented with difficult urination, gross hematuria and vague lower abdominal pain. Herein, we report a case of rhabdomyosarcoma. which revealed early recurrence and rapid growing up after partial cystectomy.
Abdominal Pain ; Adult* ; Aged ; Cystectomy ; Hematuria ; Humans ; Recurrence ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Embryonal ; Urinary Bladder* ; Urination

Ocular changes such as crescents, posterior staphyloma, retinochoroidal degeneration, lacquer cracks and subretinal or choroidal hemorrhage are common In myopia. We examined 13 patients(13 eyes) who had refractive errors of -6.0 Diopter or more and subretinal hemorrhages at initial visit. According to fluorescein angiographic finding, subretinal hemorrhages in high myopia were divided into two groups: 6 eyes without choroidal neovascularization(CNV) and 7 eyes with choroidal neovascularization. Subretinal hemorrhage without choroidal neovascularization was frequent in patients aged 15-32 years(mean, 23.7 years) and choroidal neovascularization was common in patients aged 34-60 years(mean 47.6 years). In the eyes without choroidal neovascularization, the subretinal hemorrhage disappeared spontaneously after a few months and the visual acuity of these patients was variable at the initial visit(range, 5/200-20/30), and was unchanged or improved during the follow-up period. In the eyes with choroidal neovascularization, the visual acuity was less than 0.1 at the initial visit, except 2 cases, and was unchanged or worsened during the follow-up peroid. It will be helpful to divide the high myopia with subretinal hemorrhage into with or without choroidal neovasculrization according to the flourescein angiography to assess the prognosis.
Angiography ; Choroid ; Choroid Hemorrhage ; Choroidal Neovascularization ; Fluorescein ; Fluorescein Angiography ; Follow-Up Studies ; Hemorrhage* ; Humans ; Lacquer ; Myopia* ; Prognosis ; Refractive Errors ; Visual Acuity

Accurate estimation of the exposure-response relationship between ambient urban particulate matters (PM) and public health is important for regulatory perspective of ambient urban particulate matters (PM). Ambient PM contains various transition metals and organic compounds. PM10 (aerodynamic diameter less than 10 microgram) is known to induce diverse diseases such as chronic cough, bronchitis, chest illness, etc. However, recent evaluation of PM2.5 (aerodynamic diameter less than 2.5 microgram) against health outcomes has suggested that the fine particles may be more closely associated with adverse respiratory health effects than particles of larger size. This study was performed to evaluate PM2.5-induced oxidative stress in rat lung epithelial cell in order to provide basic data for the risk assessment of PM2.5. PM2.5 showed higher cytotoxicity than PM10. Also, PM 2.5 induced more malondialdehyde (MDA) formation than PM10. In Hoechst 33258 dye staining and DNA fragmentation assay, apopotic changes were clearly detected in PM2.5 treated cells in compared to PM10. Expression of catalase mRNA was increased by PM2.5 rather than PM10. PM2.5 induced higher Mth1 mRNA than PM10. In pBR322 DNA treated with PM2.5, production of single strand breakage of DNA was higher than that of PM10. In Western blot analysis, PM2.5 induced more Nrf-2 protein, associated with diverse transcriptional and anti-oxidative stress enzymes, compared to PM10. Our data suggest that PM2.5 rather than PM10 may be responsible for PM-induced toxicity. Additional efforts are needed to establish the environmental standard of PM2.5.
Air Pollutants/chemistry/*toxicity ; Animals ; Apoptosis/physiology ; Benzimidazoles/metabolism ; Blotting, Western ; Cell Line ; Cell Survival/physiology ; DNA Fragmentation/physiology ; DNA Repair Enzymes/genetics/metabolism ; DNA-Binding Proteins/metabolism ; Epithelial Cells/drug effects/enzymology/pathology ; Formazans/metabolism ; GA-Binding Protein Transcription Factor ; Lipid Peroxides/metabolism ; Lung Diseases/*chemically induced/enzymology/pathology ; Oxidative Stress/*physiology ; RNA, Messenger/chemistry/genetics ; Rats ; Reverse Transcriptase Polymerase Chain Reaction ; Tetrazolium Salts/metabolism ; Transcription Factors/metabolism