The effect of surgical traumata upon the epiphyseal plate of the growing bone has been controversial among many authors. The resultant deformity subsequent to the epiphyseal plate injury-yields numerous different pattens and any of the explarations of the pathogenesis is also not accepted for all. Therefore, the author made an experiment to elucidate more clearly the histological changes of the epiphyseal plate of immature rabbits following insertion of Kirschner-wire and screw. Thirty rabbits weighing 700–1200gm were divided into 2 groups, as following snd the direction of longitudinal insertion from articular surface of the epiphysis of the distal femur. Group 1: lnsertion of Kirschner-wire Group 2: Insertion of screw The animals were sacrificed at 1, 2, 4, 8, and 10 weeks after the operative procedure and the histological examination of the injured epiphyseal plate of distal femur were made. The summary of the histological findings were follows: 1. The margin of the epiphyseal plate adjoining the Kirschner wire showed a new osseous tissue which formed a bony bridge running from the epiphysis to the metaphyseal bony trabeculae. 2. The margin of the damaged epiphyseal plate adjoining the screw revealed new bone formation and the amounts of the reactive new bone is less than Kirschner-wire. 3. Histological findings of the epiphyseal plate showed to be uniform and normal except in the adjacent area of the Kirschner-wire and screw.
Animals ; Clothing ; Congenital Abnormalities ; Epiphyses ; Femur ; Growth Plate ; Osteogenesis ; Rabbits ; Running ; Surgical Procedures, Operative

No abstract available.
Gastrectomy* ; Stomach Neoplasms* ; Stomach*

No abstract available.
Anesthesia, Local* ; Arthroscopy* ; Knee*

Malignant tumor is found in 1-2% of ovarian benign cystic teratomas. Among these malignant neoplasms, squamous cell carcinoma is by far the most common malignancy, whereas the incidence of struma ovarii is less than 5% in mature teratoma. As far as concerned the struma ovarii, a very small percentage is associated with carcinoid, mucinous or serous cystadenoma, or Brenner tumor. However, any reports of struma ovarii associated with squamous cell carcinoma in the same ovary could not be found in English literature. Recently we have experienced a case of squamous cell carcinoma and struma ovarii arising in an ovarian benign cystic teratoma in 72 year old female patient.
Female ; Humans ; Incidence

The alterations in the localization of keratinocyte membrane glycoconjugates in allergic contact dermatitis were investigated in guinea pig skin treated with topical application of 2.4-dinitro-chlorobenzene. We employed the avidin-biotin complex(ABC) method for the detection of localization of 10 commercially available lectins labelled with biotin: Con-A, SBA, WGA, DBA, UEA-1, RCA-1, PNA, HP, MPA, and ECA. Staining with WGA showed a remarkably decreased intensity in basal and spinous layers of the allergic skin in comparison to those of the control skin, suggesting loss of terminal sialic acids in cell membrane glycoconjugates. The other lectins showed no remarkable difference in the staining patterns between the normal and the allergic ski. The results suggest that epidermal cell membrane glycoconjugates undergoes selective perturbations in acute allergic contact dermatitis, and that the keratinocytes might be an active part of the cutaneous immune system.

Fibrous pseudotumor of the testicular tunics is a rare benign fibrous proliferative disorder, but it is the second most common mass-forining lesion of the testicular tunics. While these lesions are not strict neoplasms, they do form nodules and are often mistaken for neoplasms. Herein, we report 2 cases of fibrous pseudotumor with characteristic histologic findings. Both cases had been incidentally found as slow growing scrotal masses and underwent excision. There were several nodules along the testicular tunics which had bulging whitish-gray cut surface with focal myxoid change and a whorling appearance. These two cases showed the histologic spectrum seen in fibrous pseudotumor from a haphazard arrangement of fibroblastic type cells with intervening collagen and focal lymphocytic infiltrates in case 1, to a densely collagenized lesion in case 2.

A choledochal cyst, also referred to as cystic dilatation of bile duct, is a relatively rare lesion. Moreover, carcinoma arising from such a choledochal cyst has rarely been reported on. The incidence of carcinoma in choledochal cyst is much higher than that seen for the normal population. The mechanism of carcinogenesis in choledochal cyst is not clear, although reflux of pancreatic juice and stasis of the bile appears to be important factors. To our knowledge, there is no literature reporting on a case of choledochal cyst combined with a hilar cholangiocarcinoma. We report here on a case of choledochal cyst combined with a hilar cholangiocarcinoma in 46-year-old male patient.
Bile ; Bile Ducts ; Carcinogenesis ; Cholangiocarcinoma* ; Choledochal Cyst* ; Dilatation ; Humans ; Incidence ; Klatskin's Tumor ; Male ; Middle Aged ; Pancreatic Juice

Sixty-two patients with primary liver cancer were treated by surgical resection during a period of 10 years. There were 41 hepatocellular carcinomas, 19 cholangiocellular carcinomas, one mixed hepatocellular and cholangiocellular carcinoma, and one hepatoblastoma. Liver cirrhosis and positive hepatitis B surface antigen were noted in 78.0% and 75.7%, respectively, of the patients with hepatocellular carcinomas. In cholangiocellular carcinomas, clonorchiasis and hepatolithiasis were common associated diseases. The tumor was larger than 5 cm in 61.3% of the patients, and was multiple in 21.0%. Multiplicity of the tumor was more common in hepatocellular carcinomas, and regional lymph node metastases were present in 47.4% of the cholangiocellular carcinomas. The types of surgical procedures were a trisegmentectomy in one patient, an extended lobectomy in four, a lobectomy in 24, a segmentectomy in 12, a subsegmentectomy in 11, and a partial resection in 10. A curative resection with a negative resection margin was obtained in 75.8% of the patients. Operative morbidity developed in 29 patients (46.8%), and pulmonary problems, wound infection, and intra-abdominal abscess were common complications. The operative mortality was 3.2% (two out of 62 patients). The overall cumulative 5-year survival rate was 24.6%, and the median survival time was 14.0 months. The cumulative 5-year survival rate for hepatocellular carcinomas and cholangiocellular carcinomas were 28.2% and 20.0%, respectively. The presence of capsule formation, the absence of vascular invasion, a tumor-free resection margin, and the absence of associated liver cirrhosis were favorable prognostic factors. In patients with hepatocellular carcinomas, a high level of serum alpa -fetoprotein and a large tumor (over 5 cm) were significantly related to a shorter survival time.
Abdominal Abscess ; Carcinoma, Hepatocellular ; Cholangiocarcinoma ; Clonorchiasis ; Hepatectomy ; Hepatitis B Surface Antigens ; Hepatoblastoma ; Humans ; Liver Cirrhosis ; Liver Neoplasms* ; Liver* ; Lymph Nodes ; Mastectomy, Segmental ; Mortality ; Neoplasm Metastasis ; Survival Rate ; Wound Infection

A 69 years old, otherwise healthy male pt. was admitted and soheduled for subtotal gastrectomy under the Dx. of stornach Ca. The induction of anesthesia and beginning of Operation were smooth and unevntful. After peritoneal opening, the surgeon complained of distended stomach which was synch- ronous with ventilation. With repeating tracheogram and endoscopic examination, the authors fecund unsuspected tracheo-esophageal fistula on the low-middle esophagus. Durins convalescenee the pt, had not suffered any pulmonary complication.
Aged ; Anesthesia ; Anesthesia, General* ; Esophagus ; Fistula* ; Gastrectomy ; Humans ; Male ; Stomach ; Ventilation

The Sturge Weber syndrome is an uncommon disorder characterized by port-wine nevus of the face with angiomatosis of the ipsilateral cerebral leptomeninges and extensive calcification in the underlying cerebral cortex. Associated with this syndrome are mental retardation, choroidal angioma, buphthalmus or glaucoma, seizure and hemiplegia. We studied a case of incomplete form of Sturage Weber syndrome in a 12 year-old boy, who had generalized seizure, a homonymous hemianopsia, intracranial calcification and leptomeningeal angiomatosis. There are no characteristic facial nevus, mental retardation, occular changes and hemiplegia.