Hypereosinophilir. dermatitis, which was first described in 1981, is a clinically distinet disease within the spectrum of the hypereosinophilic syndrome. It is characterized by a generalized polymorphous pruritic eruptions and blood eosinophilia with minimal or no extracutaneous involvement known cause hypereosinophilia, namely parasites, allergies and drug association are absent in these patients. We present a patient with hypereosinophilic dermatitis who did not show evidence of systemic disease. The patient was a 18-year old male who had pruritic erythematous brownish elevated plaque on both lower extremities for 5 months. A)though the patients skin lesions improved after treatment with steroids and dapsone, after discontinuing medication, hypereosinophilia recurred.
Adolescent ; Dapsone ; Dermatitis* ; Eosinophilia ; Humans ; Hypereosinophilic Syndrome ; Hypersensitivity ; Lower Extremity ; Male ; Parasites ; Skin ; Steroids

No abstract available.
Anemia, Iron-Deficiency* ; Blood Platelets* ; Child* ; Humans ; Iron* ; Platelet Count*

BACKGROUND: Most studies of Mycoplasma pneumonia involve a group of admitted patients in hospital, usually with major medical illness. So we investigated the epidemiologic and radiologic features during the course of outbreak of pneumonia in Chunnam coastal area. METHODS: We retrospectively studied the epidemiologic and clinical feature of 105 patients with serologically proven Mycoplasma pneumonia treated at Kwang-Yang Hospital during a epidemic period of Jun. 1993 to Dec. 1993. All cases of pneumonia developed in this period were also reviewed and compared with serologically proven group. RESULTS: 1) There were 63 males and 42 females. 2) More than half(57%) of cases belonged to 5-9 years of age group, and mean age was 6.5 years old. Mean age was steadily decreased as prevalence of Mycoplasma pneumonia had been subsided. 3) A major determinant of the outbreak seemed to .to the population density rather than the population size. 4) The common radiologic features were interstitial in type, and 67 cases was restricted to one lobe. Lobar types are more common in late childhood, and interstitial or diffuse types in early childhood. CONCLUSION: These epidemiologic and radiographic characteristics would contribute to the diagnosis of Mycoplasma pneumonia.
Diagnosis ; Female ; Humans ; Male ; Mycoplasma pneumoniae* ; Mycoplasma* ; Pneumonia* ; Pneumonia, Mycoplasma* ; Population Density ; Prevalence ; Retrospective Studies

Supersoft roentgen rays called grenz rays, generated in a tube at low voltages and having wave lengths of 1 to 3 angstroms(H.V.L. 0. 01 to 0. 035mm. Al. ), are employed in the treatment of superficial derrnatoses patients (112 cases) in the Department of Dermatology, Cho Sun University hospital from March 1, 1972 to April 30, 1974. Results of these Series are as Follows: 1) Among the ll2 patients, including 28 patients of neurodermatitis, 14 patients of nummular eczema and. 10 patients of atopic dermatitis showed therapeutic success. 2) Grenz ray irradiations were remarkably effective for 6 cases of capillary hemangioma, 2 cases of basal celI epithelioma and 3 cases of verruca plana juvenilis, and less effective for psoriasis vulgaris, tinea pedis, acne vulgaris, nevus verrucosus and alopecia areata. 3) Complications included 21 cases of hyperpigmentation and burning sensations in neurodermatitis and nummular eczema.
Acne Vulgaris ; Alopecia Areata ; Burns ; Carcinoma ; Dermatitis, Atopic ; Dermatology ; Eczema ; Hemangioma, Capillary ; Humans ; Hyperpigmentation ; Neurodermatitis ; Nevus ; Psoriasis ; Sensation ; Solar System ; Tinea Pedis ; Warts

A study was made on 1,302 cases of skin tumors which were obtained mainly from surgical pathology specimen during the period of 14 years from 1973 to 1986 at Department of Dermatology in Korea University Hospital. The results were summarized as follows : 1. Of the 1,302 cases of skin tumors, 1,143 cases(87.8%) were benigh tumor, 159 cases(12.2%) of malignant tumor and male to female ratio was 1.1: l. 2. Among the 1,143 cases of benign tumors, 301 cases of epidermal cyst, 183 cases of lipoma, 173 cases of pigmented nevi and 88 cases of hemangioma were noted. 3. Among the 159 cases of malignant tumors, 46 cases of squamous cell carcinoma, 27 cases of basal cell carcinoma, 26 cases of malignant melanoma, and 17 cases of metastatic carcinoma were observed. 4. The sites of predilection of the epidermal cysts were trunk (21.9%), face (20.9%), and neck (13.9%) and lipoma was trunk (48.6%). The sites of predilection of the suamous cell carcinomas were penis (11.1%), sclap (12.9%), face (18.5%), and leg (11.1%), basal cell carcinoma was face (55.6%) and malignant melanoma was sole (26.9%). 5. Among the 17 cases of cutaneous metastatic cancer, primary sites were breast (4 cases), pancreas (1 cases), lung (2 cases), stomach (1 cases) and unkown sites (9 cases).
Breast ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Epidermal Cyst ; Female ; Hemangioma ; Humans ; Korea ; Leg ; Lipoma ; Lung ; Male ; Melanoma ; Neck ; Nevus, Pigmented ; Pancreas ; Pathology, Surgical ; Penis ; Skin* ; Stomach

Leiomyosarcoma of small intestine is an uncommon tumor, comprising less than 20 percent of all primary malignant tumors of small intestine. Duodenal leiomyosarcoma is rare disease which amount to about 20 percent of all small bowel malignancy but potentially curable tumors often diagnosed at an advanced age, so its five-year survival following resection approximates 50% in reported series. Recently, several cases of leiomyosarcomas of duodenum were diagnosed by hypotonic duodenograhy in Korea. We experienced a woman with duodenal leiomyosarcoma that was diagnosed by endoscopic duodenal biopsy and received currative resection of the tumor(Whipple's operation). We report the case with review of the literatures.
Biopsy ; Duodenum ; Endoscopy ; Female ; Humans ; Intestine, Small ; Korea ; Leiomyosarcoma* ; Rare Diseases

No abstract available.
Malocclusion*

No abstract available.
Neck* ; Urinary Bladder Neck Obstruction* ; Urinary Bladder*

Decreased sensitivity of N. gonorrhoeae to many existing antibiotics and the emergence and increase of penicillinase producing and of spectinomycin resistant N. gonorrhoeae necessitate intensive efforts to study on resistance. Male patients with uncomplicated gonococcal urethritis treated during the year 1990 at the VD clinic of Choong-ku Public Health Center in Seoul were included in this study. A total of 85 strains, 44 strains of non-PPNG and 41 strains of PPNG isolated from the patients were studied to evaluate their sensitivities to ampicillin, penicillin, cefoxitin, kanamycin, tetracycline, erythromycin, spectinomycin and cotrimazole. The results are summerized as follw: In non-PPNG strains, the range of MICs. MIC50 and MIC90 for both ampicillin and penicillin were 0.125-32, 2 and 16 mcg/ml respectively. For cefoxitin, they were 0.125-8, s and 16 mcg/ml respectively, and for kanamycin, 8--<64, 32 and 64 mcg/ml, respectively. For tetracycline, they were 1-64, 8 and 32 mcg/ml, while for erythromycin, 0.06-16, 2 and 8 mcg/ml respectively. For spectinomycin, they were 4--<64, 32 and 64 mcg/ml and for cotrimazole, 5--<160, 40 and 160 mcg/ml respectively. In the case of PPNG, the range of MICS, MIC50 and MIC90 for ampicillin were 8--<128, 32 and 128 mcg/ml respectively but for penicillin, 8--<128, 64 and 128 mcg/ml respectively. And for cefoxitin, they were 0.5-32, 4 and 16 mcg/ml while for kanamycin, 16--<64, 64 and >64 mcg/ml respectively. For tetracycline, the values were 2-64, 16 and 32 mcg/ml, and for erythromycin, they were 0.5-16, 4 and 8 mcg/ml respectively. for spectinomycin, they were 8--<64, 32, and 64 mcg/ml and finally for cotrimazole, 5--<160, 80 and 160 mcg/ml respectively. From these results, it is concluded that the MICs of both PPNG and non-PPNG were about 2 folds higher than the results of sensitivity tests at the same instituition in 1985. 2) The prevalence of PPNG among 35 gonorrhoeae patients who received treatment before the visit was 60% (21/35), while that among the patients without previous treatment was 40% (20/50). 3) In the cases of ampicillin, penicillin and cotrimazole, their MIC values were found to be significantly higher for the strains isolated from the patients with previous treatment history than those without previous treatment (p<0.05). 4) In non-PPNG strains, a significant positive correlation is found between the sensitivities to most pairs of ampicillin, penicillin, cefoxitin, kanamycin, tetracycline, erythromycin and spectinomycin. However this excludes some pairs such as : tetracycline-cefoxitin, erythromycin-penicillin, erythromycin-cefoxitin, spectinomycin-penicillin, and spectinomycincefoxitin (p<0.05). 5) In PPNG strains, a significant positive correlation is also found between the sensitivities to most pairs of ampicillin, penicillin, cefoxitin, tetracycline, erythromycin and spectinomycin. However, the exceptional cases include tetracycline-cefoxitin, erythromyoinpenicillin, erythromycin-cefoxitin, spectinomycin-penicillin, and spectinomycin-cefoxitin pairs. In addition, the sensitivity to kanamycin was found to be strongly correlated with that to tetracycline, erytheromycin and spectinomycin (p<0.05). Therefore it is essential for the management fo gonorrhoeae, together with a correct diagnosis, to use currently most effective treatment regimens which would also prevent the emergence of resistant strains. It is also suggested that when a treatment is failed, to use the durg which do not show correlation in sensitivities on re-treatment.
Ampicillin ; Anti-Bacterial Agents ; Antibodies* ; Cefoxitin ; Diagnosis ; Erythromycin ; Humans ; Kanamycin ; Male ; Penicillinase ; Penicillins ; Prevalence ; Public Health ; Seoul ; Spectinomycin ; Tetracycline ; Urethritis

PURPOSE: Osteoporosis is generally regarded as disease of women and there are extensive data about post-menopausal osteopotosis, but there is relatively little information concerning the osteoporosis in aging male. We aimed to determine the relationships between age ,androgen and bone mineral density (BMD) in elderly korean men. MATERIALS AND METHODS: We evaluated the sex hormones and BMD of 82 elderly men between May 1999 and April 2000. Serum free testosterone (FT), total testosterone (TT), DHT, LH, FSH and Prolactin were measured by RIA. BMD at anteroposterior L2-4, femoral neck, ward's triangle, femoral trochanter and femoral shaft were determined by dual-energy X-ray absorptiometry. We defined group I as free testosterone <10ng/dl and group II as 10ng/dl. RESULTS: Serum LH and FSH increased with age. There was a significant decrease in serum FT with age, but T concentrations remained unchanged. There were significant declines with age in BMD at femoral neck, Ward's triangle, femoral trochanter, femoral shaft. Serum FT were significantly correlated to BMD at anteroposterior L2-4, femoral neck, Ward's triangle, femoral trochanter, femoral shaft. After controlling for age, serum FT were significantly correlated to BMD at femoral trochanter, femoral shaft. Mean BMD was significantly lower in group I than group II at anteroposterior L2-4, femoral shaft. CONCLUSIONS: We suggest that FT is a male osteoporotic marker in man older than 50 years and bone mineral density should be considered for diagnosis of male osteoporosis associated with PADAM, especially when FT is lower than 10ng/dl.
Absorptiometry, Photon ; Aged ; Aging* ; Bone Density* ; Diagnosis ; Female ; Femur ; Femur Neck ; Gonadal Steroid Hormones ; Humans ; Male* ; Osteoporosis ; Prolactin ; Testosterone