No abstract available.
Follow-Up Studies* ; Magnetic Resonance Imaging* ; Radiculopathy*

Rhabdomyosarcoma is a highly aggressive and the most common soft tissue sarcoma in children. Sites of involvement include the orbit, the nose, the paranasal sinuses, the oropharynx, soft tissue, the nasopharynx, and the external ear or mastoid; however, the nasal vestibule, in particular, is an uncommon site. Rhabdomyosarcoma in the nasal vestibule has been reported in only one case in the literature so far and has never been reported in Korea. We experienced a case of embryonal rhabdomyosarcoma of the nasal vestibule which was managed with total excision of tumor mass and chemotherapy. We report the case and discuss the therapy and management of this unusual problem.
Child ; Drug Therapy ; Ear, External ; Humans ; Korea ; Mastoid ; Nasopharynx ; Nose ; Orbit ; Oropharynx ; Paranasal Sinuses ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Embryonal ; Sarcoma

No abstract available.
Emergencies* ; Emergency Medicine* ; Internship and Residency*

Solid pseudopapillary tumor of the pancreas is a rare tumor that affects young females with low malignant potential and good prognosis with more than 90% survival at 5 years. Metastasis is very rare. We report the case of a 74-year-old female who had pancreatic solid-pseudopapillary tumor and synchronous hepatic metastasis.
Aged ; Female ; Humans ; Neoplasm Metastasis ; Pancreas ; Pancreatic Neoplasms ; Prognosis

No abstract available.
Shoulder Fractures*

Basaloid squamous cell carcinoma (BSCC), an uncommon tumor with predilection for the upper aerodigestive tract, is a distinct variant of squamous cell carcinoma, because of its unique histological features and ominous clinical behavior. Basaloid squamous cell carcinoma is a high-grade variant of squamous cell carcinoma. Reports subsequent to its initial description in 1986 by Wain et al. have confirmed that the head and neck region is the most frequently involved region, with majority of the cases arising in the supraglottic larynx, hypopharynx, tonsil and base of tongue. Other head and neck sites include the palate, buccal cavity, floor of mouth, nasopharynx, trachea, and sinonasal tract. BSCC is not limited to the head and neck region but has also been described in the esophagus, lung, thymus, anus and cervix among other sites. We experienced and treated a case of BSCC extended to the temporal bone with characteristic histopathologic and immunologic features. Therefore, we report here the rare case of BSCC invading the temporal bone with literature.
Anal Canal ; Carcinoma, Squamous Cell* ; Cervix Uteri ; Esophagus ; Female ; Head ; Hypopharynx ; Larynx ; Lung ; Mouth Floor ; Nasopharynx ; Neck ; Palate ; Palatine Tonsil ; Temporal Bone* ; Thymus Gland ; Tongue ; Trachea

BACKGROUND AND OBJECTIVES: Fas and Fas ligand (Fas-L) interactions mediate apoptosis of eosinophils. It is possible that reduction of Fas/Fas-L or Fas-L expression on eosinophils could induce the eosinophilia seen in Samter's triad. The purpose of this study was to analyse the release of LT and Fas/Fas-L expression pattern following exposure to varying concentrations of aspirin in aspirin sensitive nasal polyp (ASP) and non-aspirin sensitive nasal polyp (NASP) patients. MATERIALS AND METHODS: Twenty NASP patients and 16 ASP patients were recruited. Nine healthy subjects served as normal controls. LT levels and Fas/Fas ligand expressions were analysed by ELISA and flow cytometry. RESULTS: Both NASP and ASP patients showed increased release of LT on aspirin exposure in blood and nasal polyps. But ASP patients showed an even greater release of LT on aspirin exposure in blood as compared to NASP patients (p<0.05). LT release from peripheral blood elements do not necessarily coincide with those results obtained from nasal polyps. Eosinophils in ASP patients have significantly decreased Fas expression when compared to NASP patients (p<0.0001). CONCLUSION: These results suggested the role of LT and eosinophils in aspirin intolerance mechanisms in both blood and nasal polyp tissues. The decreased expression of the Fas receptor or defect of Fas/Fas-L interaction could be an important role in pathogenesis of nasal polyp regardless of their association with aspirin sensitivity.
Antigens, CD95 ; Apoptosis ; Aspirin* ; Enzyme-Linked Immunosorbent Assay ; Eosinophilia ; Eosinophils ; Fas Ligand Protein ; Flow Cytometry ; Humans ; Nasal Polyps* ; Viperidae

PURPOSE: To determine the relationship between expression pattern of E-cadherin, Beta-catenin and cyclin D1, and clinicopathologic parameters in patients with head and neck squamous cell carcinomas (HNSCC). MATERIALS AND METHODS: The authors evaluated the immunohistochemical expression pattern of E-cadherin, Beta-catenin in relationship with cyclin D1 overexpression, degree of histologic differentiation, clinical stage, and nodal status in 146 head and neck squamous cell carcinomas (HNSCC). The authors also evaluated the expression of E-cadherin/Beta-catenin complex, E-cadherin/cyclin D1, and Beta-catenin/cyclin D1 double staining with confocal laser scanning microscope. RESULTS: Aberrant expressions in 78% of E-cadherin, 77% of Beta-catenin, and 69% of cyclin D1 in the HNSCC were observed. There was correlation of aberrant expression of E-cadherin and nodal status. Cyclin D1 overexpression was also correlated to clinical stage and nodal status. Significant relation was observed between E- cadherin and Beta-catenin expression patterns. Co-expression of E-cadherin and Beta-catenin was significantly detected. However, there was no correlation of cyclin D1 overexpression with E-cadherin or Beta-catenin expression patterns. CONCLUSION: These results suggest that aberrant expression of E-cadherin, E-cadherin/Beta-catenin complex, and cyclin D1 may be involved in clinical stage and/or nodal status, and analysis of the pattern of E-cadherin, cyclin D1, and E-cadherin/Beta-catenin complex may be good prognostic marker of HNSCC.
beta Catenin ; Cadherins ; Carcinoma, Squamous Cell* ; Cyclin D1* ; Cyclins* ; Head* ; Humans ; Neck* ; Prognosis

Hemangiopericytoma is an uncommon vascular tumor described first by Stout and Murray in 1942. These tumors arise from Zimmerman's pericytes, which are found outside capillaries and postcapillary venules. Although hemangiopericytomas are well characterized, many controversies still exist regarding their malignant potential and management. The hemangiopericytomas usually present as rapidly growing, painless masses. They are usually detected because of their rapid growth, or become symptomatic secondary to compression of adjacent structures. Pain occurs with local invasion or bony metastasis. The hemangiopericytoma in the nasal cavity and paranasal sinus often has local recurrence but appears to be a lower grade malignancy. And wide surgical excision is the treatment of the choice. We report a case of hemangiopericytoma occurred in the right nasal cavity and paranasal sinus treated by median maxillectomy via lateral rhinotomy incision.
Capillaries ; Hemangiopericytoma* ; Nasal Cavity* ; Neoplasm Metastasis ; Pericytes ; Recurrence ; Venules

No abstract available.
Ossicular Prosthesis*