No abstract available.
Appendectomy* ; Lymphocyte Subsets* ; Lymphocytes*

No abstract available.
Hemorrhoids*

No abstract available.
Drainage* ; Humans ; Retrospective Studies*

BACKGROUND: Palpable breast tumors have traditionally been diagnosed with open biopsy. We propose fine needle aspiration (FNA) cytology as a reliable, safe initial procedure in these patients. METHODS: We performed 248 fine needle aspiration (FNA) cytology of breast tumors, among which 106 cases were histologically examined during the period of form Jan. 1994 to Dec. 1997 at the Department of Surgery, Chonbuk National University Hospital. RESULTS: Main clinical symptom was palpable mass on breast at the time she visited the hospital. Clinical diagnosis based on symptoms and physical examination had 96.9% of sensitivity, 57.5% of specificity. Based on definite histologic diagnosis, the sensitivity of FNA cytology was 96.9% specificity 91.7%, diagnostic accuracy 93.5%, respectively. 86.1% of cytologic malignancy were proven malignant histologically, and 100% of cytologically benign cases turned out hitologically benign. CONCLUSIONS: A fine needle aspiration (FNA) cytology of solid palpable breast lesions should be diagnostic procedure of choice for those patients classified clinically as probably benign or clinically as malignant.
Biopsy ; Biopsy, Fine-Needle* ; Breast Neoplasms ; Breast* ; Diagnosis ; Humans ; Jeollabuk-do ; Physical Examination ; Sensitivity and Specificity

No abstract available.
Charcoal* ; Drug Therapy* ; Mitomycin* ; Stomach Neoplasms*

The malignant fibrous histiocytoma (MFH) was first introduced in 1963 to refer to a group of soft-issue tumors characterized by a storiform or cartwheel-ike growth pattern and predominantly fibroblastic appearance. It was postulated that they were derived from histiocytes that could assume the appearance and function of fibroblasts. MFH has been recognized to be the most common sarcoma in the soft tissue of late adult life which involves the deep fascia or skeletal muscles of the extremities or retroperitoneum. It has been noted in other organs, however, it rarely arises in the liver. We report two cases of primary malignant fibrous histiocytoma of the liver histopathologically confirmed after surgical resection-storiform pleomorphic and myxoid subtypes in the 55 year old male and 49 year old female patients, respectively, and describes the clinical courses, characteristics and pathologic aspects with review of the related literatures.
Adult ; Extremities ; Fascia ; Female ; Fibroblasts ; Histiocytes ; Histiocytoma, Malignant Fibrous* ; Humans ; Liver* ; Male ; Middle Aged ; Muscle, Skeletal ; Sarcoma

The factors affecting the survival rate of breast-cancer patients were studied in 185 cases treated at the Department of Surgery, College of Medicine, Chonbuk National University from January 1987 to December 1996. The results are as follows: 1) The most prevalent age group was the 5th decade (57 cases, 30.8%). 2) The most common initial symptom was a palpable mass (167 cases, 90.3%). 3) In 134 cases (72.4%), the patients visited the hospital within 6 months of the onset of the first symptom. 4) The primary tumor was located on the left side in 101 cases (54.6%) and on the right side in 84 cases (45.4%), and the most frequent tumor location was the upper outer quadrant (113 cases, 61.1%). 5) The pathological types, according to the WHO classification, were an invasive ductal carcinoma (179 cases, 96.7%) and a medullary carcimona (22 cases, 11.9%) in that order. 6) According to the TNM system, the most common stage was stage II (100 cases, 54.1%). The overall 5-year survival rates according to pathologic stage were 96.0% for Stage I, 83.1% for Stage II, 67.8% for Stage III, and 12.5% for Stage IV. 7) The estrogen and the progesterone receptor status had no significance for the survival rate. 8) The most common type of operation was a modified radical mastectomy (Patey) (150 cases, 81.0%). 9) Axillary lymph node metastases were present in 77 cases (41.6%). 10) The most common distant metastasis was the bone (12 cases, 6.5%). 11) The overall 5-year actuarial survival rate after surgery was 76.6%. The 5-year survival rates according to the number of invaded lymph-node were 83.5% for 0 nodes, 77.6% for 1~3 nodes, 57.5% for 4~9 nodes, and 49.4% in cases of more than 10 nodes.
Breast Neoplasms* ; Breast* ; Carcinoma, Ductal ; Classification ; Estrogens ; Humans ; Jeollabuk-do ; Lymph Nodes ; Mastectomy, Modified Radical ; Neoplasm Metastasis ; Receptors, Progesterone ; Survival Rate

Peritoneal lavage cytology was performed at the time of gastrectomy for 295 patients with gastric cancer from September 1991 to January 1996 in the Department of Medical Sciences,Chonbuk National University Graduate School. The results were as follows;1) Positive intraperitoneal free cancer cells were observed in 9.8% of all case. And,the higher the S-category, the higher the increase in positive intraperitoneal free cancer cells, but the lower the rate of survival. 2) The higher the spatial extent of the invasion of the gastric serosa,the higher the increase in the positive intraperitoneal free cancer cells. However, There was no statiscal relation between the areas of gastric serosa invasion and the 3-year survival rate. But, especially when the areas of serosa invasion are 5-10cm2, the 3-year survival rate was statiscally higher in the negative intraperitoneal free cancer cell group than in the positive free cancer cell group.(P<0.012). 3) The rate of positive intraperitoneal free cancer cells become higher progressively with increasing the peritoneal invasion, but, there were no 3-year survival patients who have positive peritoneal invasion . In patients with no evidence of peritoneal spread, negative intraperitoneal free cancer cell group had a statistically signigficant higher 3-year survival rate than the positive group.(P<0.0004). 4) For histopathological types of tumors, the incidence of positive intraperitoneal free cancer cells was higher in undifferentiated adenocarcinomas than in differentiated types, though the difference was statistically insignificant. For signet-ring cell carcinomas, the 3-year survival rate of the negative intraperitoneal free cancer cell group was statistically higher than that of the positive group.(P<0.0005). 5) The incidence of positive intraperitoneal free cancer cells increased as the stage of gastric cancer increased, but the survival rate was decreased. 6) In the noncurative resection group, the incidence of positive intraperitoneal free cancer cells was higher, but the survival rate was lower, than in the curative resection group. The 3-year survival rates were higher for the patients with curative resection and negative intraperitoneal free cancer cells than for the patients with curative resection and positive intraperitoneal free cancer cells (P<0.0009). The difference in the 3-year survival rate between the noncurative resection with positive intraperitoneal free cancer cell group and the noncurative resection with negative intraperitoneal free cancer cell group was stastistically significant. (P<0.0000). 7) For the types of recurrence, hematogenous metastasis was the most common type of recurrence in the negative intraperitoneal free cancer cell group; peritoneal metastasis was the most common type of recurrence in the positive intraperitoneal free cancer cell group. In conclusion; at the time of gastrectomy, peritoneal lavage cystology is very impotant and basic examination which can help early detection of intraperitoneal free cancer cells. Therefore, when intraperitoneal free cancer cells are negative,radical curative gastrectoy make the high survival rate of patients.
Adenocarcinoma ; Gastrectomy ; Humans ; Incidence ; Neoplasm Metastasis ; Peritoneal Lavage ; Prognosis* ; Recurrence ; Serous Membrane ; Stomach Neoplasms ; Survival Rate

Primary hyperparathyroidism is a relatively rare disease entity in Korea. It is characterized by severe skeletal and renal changes due to hypersecretion of parathyroid hormone and rarely shows peptic ulceration, hypertension, pancreatitis and impaired mentality. Primary hyperparathyroidism is most commonly caused by an adenoma, or hyperplasia and rarely by cancer of the parathyroid gland. The authors experienced a case involving a giant parathyroid adenoma in a 62-year-old female. The main symptoms were general weakness, anorexia, and constipation. We detected the giant parathyroid adenoma on the anterior neck by using preoperative localization methods, such as ultrasonography, and a thallium-technetium subtraction scan. A parathyroidectomy was carried out, and the parathyroid adenoma measured 5.0 cm 3.2 cm in size and 12 gm in weight. Clinical laboratory reports and symptoms were normalized with no sequelae. We report this case with a review of the literature related to sizes and weights of adenomas.
Adenoma ; Anorexia ; Constipation ; Female ; Humans ; Hyperparathyroidism, Primary* ; Hyperplasia ; Hypertension ; Korea ; Middle Aged ; Neck ; Pancreatitis ; Parathyroid Hormone ; Parathyroid Neoplasms* ; Parathyroidectomy ; Peptic Ulcer ; Rare Diseases ; Ultrasonography ; Weights and Measures

The Krukenberg tumor refers to a wide variety of cancers that metastasize in the ovaries with well defined histopatholoigical characteristics and in over half of all cases they metastasize bilaterally. The ovary is a relatively frequent site of metastasis from malignant neoplasia arising elsewhere in the body- in a majority of instances the gastrointestinal tract, breast or other gynecologic organs. The bile duct and gallbladder are a rare source of metastasis. The microscopic appearance of these metastases is as varied as that of the primary cancers. The best known tumor of this type is a mucin secreting signet-ring cell adenocarcinoma of gastric origin. We report a case of a 50-year-old woman with a Krukenberg tumor with galactorrhea diagnosed by surgical resection. She has a past history of surgical treatment for Klatskin tumor which invaded the Hartman's pouch of gallbladder directly one year before this operation. Histologic examination revealed that the proximal and distal margin of bile duct were free of disease, and the level of CA 19-9 returned to normal at 2 months after surgical intervention. During the period of follow-up, she notified the sudden onset of increased serum level of CA 19-9 with hyperprolactinemia at that time point. However no evidence of hepatic recurrence was found despite pelvic evidence of diffuse recurrence. Radical pelvic surgery was accomplished in this patient by hysterosalpingo-oophorectomy.
Adenocarcinoma ; Bile Ducts ; Breast ; Female ; Follow-Up Studies ; Galactorrhea ; Gallbladder ; Gastrointestinal Tract ; Humans ; Hyperprolactinemia ; Klatskin's Tumor* ; Krukenberg Tumor* ; Laparotomy* ; Middle Aged ; Mucins ; Neoplasm Metastasis ; Ovary ; Pregnancy ; Prolactin* ; Recurrence