1.Bacteriologic Study on Normal Conjunctival Flora and Change of Antibiotic Susceptability.
Hyung Jun PARK ; Ga Young YI ; Nam Ju MOON
Journal of the Korean Ophthalmological Society 2001;42(6):817-824
We evaluated the distribution of normal conjuctival flora and the change of antibiotic sensitivity of cultured bacteria. Specimens were obtained from inferior conjunctiva cul de sac with sterile cotton-tipped applicator from healthy 216 human beings. Antibiotic sensitivity test was done by disk diffusion method. The results indicated that overall positive culture rate was 47.7% and major organisms were Coagulase-negative Staphylococcus(55.7%), Staphylococcus aureus(16%), Gram negative bacteria(7.5%), Streptococcus(4.7%). Antibiotic sensitivity test of cultured Gram positive bacteria demonstrated less than 60% rate of susceptability in gentamicin, tetracyclin, erythromycin and 80.5% rate of susceptability in ciprofloxacin. Gram negative bacteria demonstrated less than 60% rate of susceptability in cephalothin, ampicillin. From the above results, we concluded that antibiotic resistance of normal conjunctival flora was increased from the past and the principle of antiviotic eye drop use should be emphasized.
Ampicillin
;
Bacteria
;
Cephalothin
;
Ciprofloxacin
;
Conjunctiva
;
Diffusion
;
Drug Resistance, Microbial
;
Erythromycin
;
Gentamicins
;
Gram-Negative Bacteria
;
Gram-Positive Bacteria
;
Humans
;
Staphylococcus
2.Lumpectomy as a Surgical Treatment of Primary Benign Pleomorphic Adenoma of the Parotid Gland.
Hyung Suk YI ; Jun Sik KIM ; Nam Gyun KIM ; Kyung Suk LEE ; Yoon Jung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2010;37(4):447-451
PURPOSE: Pleomorphic adenoma is the most common benign neoplasm in parotid gland. Superficial parotidectomy was usually used to remove the pleomorphic adenoma. But, this method has to remove tumor with normal parotid tissue. Authors did lumpectomy to remove pleomorphic adenoma in parotid gland, because pleomorphic adenoma is wrapped in a capsule as it grows. The purpose of this study is to evaluate the efficacy of lumpectomy as a treatment of pleomorphic adenoma in parotid gland. METHODS: From 2002 to 2008, 8 patients underwent the lumpectomy of the pleomorphic adenoma in parotid gland. Occurrence of the complications and recurrance were evaluated. RESULTS: Patients were followed-up for a mean 45 months. There were no recurrance or no complication after lumpectomy. CONCLUSION: Authors suggest that the lumpectomy lead to decrese complications, recurrane and can be used as a procedure for the resection of pleomorphic adenoma in parotid gland.
Adenoma, Pleomorphic
;
Humans
;
Mastectomy, Segmental
;
Parotid Gland
3.Simple Identification of Symmetric Reduction in Unilateral Depressed Zygomatic Fracture.
Hyung Suk YI ; Kyung Suk LEE ; Jun Sik KIM ; Nam Gyun KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2010;37(2):195-198
PURPOSE: The zygoma is a key element which composes the facial contour. Zygomatic fracture induces facial asymmetry. We use radiologic evaluation or inspections mainly for identification of symmetry after reduction depressed zygomatic fracture. But the disadvantages of such methods are time-consuming and complicated process. So we tried to develop a new testing method with a ruler and a level. METHODS: In unilateral depressed zygomatic fracture patient, parallel to the patient's head to make sure lay horizontaly. Put the leg of a ruler on the malar eminence so that it is at the same distance from the facial midline. Then take the level of malar eminence as put the level above the ruler. This process was performed before and after the reduction. RESULTS: We were able to fix with plate and screw after checking the results of reduction fast and easily. Good results were obtained at post-operative radiologic evaluation. CONCLUSION: We can easily get the ruler and level around life. This method is not only simple but also short-time process compared with other method-radiologic evaluation or inspection. And the operator can explain the results to the patients easily and objectively. Authors obtained the good results with this new method, and would introduce it for another method of identifying the result of reduction in depressed zygomatic fractures.
Facial Asymmetry
;
Head
;
Humans
;
Leg
;
Zygoma
;
Zygomatic Fractures
4.Subcellular localization of the transmembrane inner ear (Tmie) protein in a stable Tmie-expressing cell line.
Sankarapandian KARUPPASAMY ; Yoon Yi NAM ; Harry JUNG ; Byoungkwon PARK ; Hyung Joo KWON ; Jun Gyo SUH
Laboratory Animal Research 2011;27(4):339-342
Mutations in the transmembrane inner ear (Tmie) gene, which encodes the Tmie protein, have been attributed to deafness autosomal recessive 6 (DFNB6), an autosomal nonsyndromic recessive hearing loss disorder. Although the Tmie gene was identified a few years ago, little is known about subcellular localization of the Tmie protein. In order to address this, we developed a stable cell line expressing Tmie protein. The expression of Myc-tagged Tmie protein was confirmed by Western blot analysis using an anti-Myc antibody and localization of the Tmie protein was confirmed by immunostaining, using the anti-Myc antibody as well as the anti-tmie antibody. Our study demonstrates that the Tmie protein is localized mostly in the cellular membrane and to a lesser extent in cytoplasm. These results suggest that our Tmie expressing stable cell line provides a suitable in vitro model to explore Tmie synthesis and functions.
Blotting, Western
;
Cell Line
;
Cytoplasm
;
Deafness
;
Ear, Inner
;
Hearing Loss
;
Membranes
5.Result of Modular Necks in Primary Total Hip Arthroplasty with a Average Follow-up of Four Years.
Jemin YI ; Kye Young HAN ; Young Jun NAM ; Keun Woo KIM
Hip & Pelvis 2016;28(3):142-147
PURPOSE: This study aimed to investigate the outcomes of modular neck-utilization in primary total hip arthroplasty (THA). MATERIALS AND METHODS: Thirty patients (34 hips) who had modular stem THA between April 2011 and January 2013 were evaluated. There were 19 men and 11 women with a mean age of 61.2 years at the time of surgery. There were 20 cases of osteonecrosis of femoral head, 7 cases of osteoarthritis, 6 cases of femur neck fracture, and 1 case of rheumatoid arthritis. No patients presented with anatomical deformity of hip. Patients were operated on using a modified Watson-Jones anterolateral approach. All patients underwent clinical and radiological follow-up at 6 weeks, 3, 6, and 12 months, and every year postoperatively. The mean duration of follow-up was 48.2 months (range, 39 to 59 months). RESULTS: The average Harris hip score improved from 63.7 to 88.1 at the final follow-up. Radiographically, mean acetabular cup inclination was 45.3°(range, 36°-61°) and anteversion was 21.7°(range, 11°-29°). All were neutral-positioned stems except 5 which were varus-positioned stems. In only 3 cases (8.8%), varus or valgus necks were required. A case of linear femoral fracture occurred intraoperatively and 1 case of dislocation occurred at postoperative 2 weeks. No complications at modular junction were occurred. CONCLUSION: Our study shows that the use of modular necks had favorable clinical and radiographic results. This suggests that the use of modular neck in primary THA without anatomical deformity is safe at a follow-up of 39 months.
Acetabulum
;
Arthritis, Rheumatoid
;
Arthroplasty
;
Arthroplasty, Replacement, Hip*
;
Congenital Abnormalities
;
Dislocations
;
Female
;
Femoral Fractures
;
Femoral Neck Fractures
;
Follow-Up Studies*
;
Head
;
Hip
;
Humans
;
Male
;
Neck*
;
Osteoarthritis
;
Osteonecrosis
6.Focal Sparing of the Fatty Liver Caused by a Nontumorous Arterioportal Shunt.
Min Woo LEE ; Young Jun KIM ; Hae Jeong JEON ; Nam Ju LEE ; Sung Gyu MOON ; Jeong Geun YI
Journal of the Korean Society of Medical Ultrasound 2007;26(2):83-87
We present two cases of focal fatty sparing caused by a nontumorous arterioportal shunt. Two patients underwent ultrasonography (US) as a part of routine medical screening, which revealed a hypoechoic lesion in the diffuse fatty liver. Each lesion appeared to be an arterioportal shunt on triphasic mutidetector computed tomography (CT) and was seen as being slightly hyperdense on noncontrast CT. No tumors were delineated around or within the arterioportal shunt. Both lesions remained unchanged on six-month follow-up US.
Fatty Liver*
;
Follow-Up Studies
;
Humans
;
Mass Screening
;
Ultrasonography
7.Role of Pulmonary Metastasectomy of Hepatocellular Carcinoma after Liver Transplantation.
Hyun Soo KIM ; Kyung Suk SUH ; Young Min JUN ; Taehoon KIM ; Woo Young SHIN ; Nam Joon YI ; Kook Nam HAN ; Young Tae KIM ; Tae You KIM ; Kuhn Uk LEE
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2009;13(4):251-258
PURPOSE: Liver transplantation (LT) has been advocated as a good management option for patients with hepatocellular carcinoma (HCC). The rate of HCC recurrence after LT is about 20%. Although the median survival time of patients with HCC recurrence is 7~9 months, the role of surgical treatment for metastatic tumors has been reported on. In this study, we evaluated the role of metastasectomy for treating patients with pulmonary metastasis from HCC after LT. METHODS: We retrospectively analyzed 10 patients with pulmonary metastasis after LT and who were treated between April 2005 and October 2007. The underlying liver disease was cirrhosis caused by chronic viral hepatitis. The surveillance protocol for HCC recurrence was as follows: assessing the serum alpha-fetoprotein level every 1 month, chest and abdomen-pelvic computed tomography every 3 months and a bone scan every 1 year or when bone metastasis was suspected. The patients with less than 3 metastatic lesions were recommended to undergo metastasectomy (Group S, n=6) and the patients with more 4 lesions were recommended nonsurgical management, including chemotherapy (Group N, n=4). RESULTS: All the metastatic lesions were detected on the protocol chest CT scans. The median recurrence time was 7.4 months (0.8~18.2) after LT; this was 11.0 (4.8~18.2) months for Group S and 2.0 (0.8~3.3) months for Group N. One patient had a single lesion and the others had multiple lesions on multilobes. The median survival times of Group S were 29.3 (18.5~41.3) months after pulmonary metastasis and 40.3 (23.3~48.0) months after transplantation; 5 patients had no recorded evidence of their disease status. The median survival time of Group N was 4.3 (4.0~6.3) months after metastasis and 6.2 (5.3~7.1) months after transplantation; all the patients have since died. CONCLUSION: The survival outcome seemed to be good for the patients who underwent pulmonary metastasectomy for HCC, if it was detected earlier and it was resectable (< or =3 lesions). However, further study is required for validating the survival benefit of pulmonary metastasectomy.
alpha-Fetoproteins
;
Carcinoma, Hepatocellular
;
Fibrosis
;
Hepatitis
;
Humans
;
Liver
;
Liver Diseases
;
Liver Transplantation
;
Metastasectomy
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Thorax
8.Role of Pulmonary Metastasectomy of Hepatocellular Carcinoma after Liver Transplantation.
Hyun Soo KIM ; Kyung Suk SUH ; Young Min JUN ; Taehoon KIM ; Woo Young SHIN ; Nam Joon YI ; Kook Nam HAN ; Young Tae KIM ; Tae You KIM ; Kuhn Uk LEE
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2009;13(4):251-258
PURPOSE: Liver transplantation (LT) has been advocated as a good management option for patients with hepatocellular carcinoma (HCC). The rate of HCC recurrence after LT is about 20%. Although the median survival time of patients with HCC recurrence is 7~9 months, the role of surgical treatment for metastatic tumors has been reported on. In this study, we evaluated the role of metastasectomy for treating patients with pulmonary metastasis from HCC after LT. METHODS: We retrospectively analyzed 10 patients with pulmonary metastasis after LT and who were treated between April 2005 and October 2007. The underlying liver disease was cirrhosis caused by chronic viral hepatitis. The surveillance protocol for HCC recurrence was as follows: assessing the serum alpha-fetoprotein level every 1 month, chest and abdomen-pelvic computed tomography every 3 months and a bone scan every 1 year or when bone metastasis was suspected. The patients with less than 3 metastatic lesions were recommended to undergo metastasectomy (Group S, n=6) and the patients with more 4 lesions were recommended nonsurgical management, including chemotherapy (Group N, n=4). RESULTS: All the metastatic lesions were detected on the protocol chest CT scans. The median recurrence time was 7.4 months (0.8~18.2) after LT; this was 11.0 (4.8~18.2) months for Group S and 2.0 (0.8~3.3) months for Group N. One patient had a single lesion and the others had multiple lesions on multilobes. The median survival times of Group S were 29.3 (18.5~41.3) months after pulmonary metastasis and 40.3 (23.3~48.0) months after transplantation; 5 patients had no recorded evidence of their disease status. The median survival time of Group N was 4.3 (4.0~6.3) months after metastasis and 6.2 (5.3~7.1) months after transplantation; all the patients have since died. CONCLUSION: The survival outcome seemed to be good for the patients who underwent pulmonary metastasectomy for HCC, if it was detected earlier and it was resectable (< or =3 lesions). However, further study is required for validating the survival benefit of pulmonary metastasectomy.
alpha-Fetoproteins
;
Carcinoma, Hepatocellular
;
Fibrosis
;
Hepatitis
;
Humans
;
Liver
;
Liver Diseases
;
Liver Transplantation
;
Metastasectomy
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Thorax
9.A Case of Periosteal Chondroma of the Cervical Spine: Case Report.
Hyeong Joong YI ; Young Soo KIM ; Hyung Suk LEE ; Seung Ro LEE ; Chang Kok HAHM ; Yong KO ; Seong Hoon OH ; Suck Jun OH ; Nam Kyu KIM ; Kwang Myung KIM
Journal of Korean Neurosurgical Society 1995;24(5):601-607
The authors experienced a case of cervical periosteal chondroma presenting with symptoms of spinal cord compression in 26-year-old woman. The diagnosis was based on the characteristic features of computed tomographic scan and magnetic resonance imaging scan. Total surgical removal in two-staged operation was followed by full neurological recovery. Extensive spinal canal and extradural involvement in case of chondroma of the cervical vertebral column was observed and rarely reported in this literature.
Adult
;
Chondroma*
;
Diagnosis
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Spinal Canal
;
Spinal Cord Compression
;
Spine*
10.Abdominal Aortic Aneurysm Infection Caused by Citrobacter freundii.
Je Ho YI ; Sang Jun PARK ; Yu Gene OH ; Dong Woo KANG ; Chang Woo NAM ; Joseph JEONG ; Hee Jeong CHA ; Hong Rae CHO
Journal of the Korean Society for Vascular Surgery 2008;24(1):60-63
Citrobacter freundii is frequently isolated in antimicrobial-resistant nosocomial infections. Many strains of Citrobacter freundii are capable of producing an inducible broad-spectrum beta-lactamase. We report a case of an abdominal aortic aneurysm infected with Citrobacter freundii. A 55-year-old woman presented with acute lower back pain. Contrast enhanced computed tomography revealed a saccular aneurysm of the infrarenal abdominal aorta, with impending rupture. She underwent emergency surgery, during which a segment of aneurysmal aorta and infected tissue were completely removed and an in situ graft was placed for vascular reconstruction. The anastomotic site and inserted graft were wrapped with greater omentum. Citrobacter freundii was isolated by tissue culture from the resected aneurysmal wall.
Aneurysm
;
Aorta
;
Aorta, Abdominal
;
Aortic Aneurysm, Abdominal
;
beta-Lactamases
;
Citrobacter
;
Citrobacter freundii
;
Cross Infection
;
Emergencies
;
Female
;
Humans
;
Low Back Pain
;
Middle Aged
;
Omentum
;
Rupture
;
Transplants