No abstract available.
Neurilemmoma*

No abstract available.
Chordoma*

A retrospective study 40 patients with moderate or severe diffuse axonal injury which is defined as posttraumatic coma for over 24 hours without mass lesions or ischemic insults was conducted in order to identify prognostic parameters. The sign of hypothalamic damage and motor reactivities of 40 patients were reviewed and compared to the outcome. The results were as follows ; 1) The ratio of male to female was about 3 to 1 and the peak incidence was at the first decade. 2) Of abnormal brain stem signs, fever of central origin was observed at the early posttraumatic phase and correlated with nonrecovery of consciousness(P<0.05). 3) Of abnormal brain stem signs, abnormal ADH secretion was significantly correlated with nonrecovery of consciousness(P<0.005). 4) Abnormal motor reactivity to pain was significantly correlated with nonrecovery of consciousness(P<0.005). 5) In the group of recovery of consciousness, initial Glasgow coma scale in 40 patients with moderate or severe DAI was significantly correlated with their outcome(P<0.005).
Brain Stem ; Coma ; Consciousness ; Diffuse Axonal Injury* ; Female ; Fever ; Glasgow Coma Scale ; Humans ; Incidence ; Male ; Retrospective Studies

A retrospective study was made in 21 patients who angiographically diagnosed as moyamoya or moyamoya-like disease over the last 10 years. Computed tomography of the patients showed semorrhage, infarction or normal. Carotid angiography revealed various stages unilaterally or bilaterally. Seventy-five percent of the venous phase on the side of arterial occlusion demonstranted some abnormalities. Two children with unilateral abnormality showed arterial occlusion at supraclinoid portion of internal carotid arteries. On the other hand 5 adults with unilateral abnormality showed occlusion at variable sites of internal carotid artery.
Adult ; Angiography ; Carotid Artery, Internal ; Child ; Hand ; Humans ; Infarction ; Moyamoya Disease* ; Retrospective Studies

Anisakiasis refers to the infestation of humans by species of marine nematode larvae belonging to the subfamily Anisakiae. An acute abdominal symptom may occur after ingestion of raw marine fish containing nematode larvae of the genus Anisakis. Migration of the parasite into the wall of gtomach, small intestine or, less commomly, the colon elicits a striking eosinophilic granulomatous tissue response. A 39 year old man was visited St. Vincent Hospital because of abdominal distension and tenderness. The plain abdominal X-ray showed ileus pattern suggesting intestinal obstruction. Hence we presented a case of intestinal Anisakiasis combined with intstinal obstruction.
Adult ; Anisakiasis* ; Anisakis ; Colon ; Eating ; Eosinophils ; Humans ; Ileus ; Intestinal Obstruction ; Intestine, Small ; Larva ; Parasites ; Strikes, Employee

OBJECTIVE: We report an investigation of cerebral blood flow(CBF) and the expression of p53 and p21 at peri-infarct area of focal cerebral infarction in rats. METHODS: Adult Sprague-Dawley male rats were used for the experiment. In Group 1(n=7), the right middle cerebral artery(MCA) was coagulated. In Group 2(n=11), the right MCA and common carotid artery(CCA) were coagulated, and the left CCA was occluded for 30 minutes. Cerebral blood flow was measured at two areas, 2mm and 8mm distal to the MCA coagulation site. The rats were killed after 24 hours. After immunohistochemical staining, the width of the p53 or p21 positive area was measured. The p53 and p21 positive glial cells were counted at the peri-infarct area adjacent to the infarction core in Group 2. RESULTS: A focal infarction was found invariably in Group 2. CBF's at 2 mm and 8 mm areas were 8.3+/-2.1, 36.4+/-4.2 in Group 1 and 0.0+/-0.0, 6.7+/-1.5ml/100g/min in Group 2, respectively. All of the measured CBF's except that of the 8mm site in Group 1 were significantly lower than preoperative level(p<0.001), which were between 20.8+/-4.5% and 16.3+/-3.3% of preoperative CBF. The ratio of p21 and p53 positive cells was 1.0+/-0.1. CONCLUSION: We could note that the expression of p53 and p21 was the highest at an adjacent peri-infarct area. The degree of CBF reduction is more responsible for infarction than CBF itself.
Adult ; Animals ; Cerebral Infarction* ; Humans ; Infarction ; Male ; Neuroglia ; Rats* ; Rats, Sprague-Dawley

No abstract available.
Cell Line* ; Glioblastoma* ; Humans*

We experienced 2 cases of cauda equina syndrome with lumbar and lumbosacral disc herniations. They have symptoms of motor paralysis, decreased deep tendon reflex, sensory change on the corresponding dermatome or saddle area, and bladder dysfunction. We had performed neurologic examination, simple spine radiography, lumbosacral myelography, computed tomography, and cystometry for diagnosis. Patients were received operations of laminectomy and discectomy, and revealed significant degree of recovery on motor or sensory change but, not for the bladder dysfunction.
Cauda Equina* ; Diagnosis ; Diskectomy ; Humans ; Laminectomy ; Myelography ; Neurologic Examination ; Paralysis ; Polyradiculopathy* ; Radiography ; Reflex, Stretch ; Spine ; Urinary Bladder

Of eighty-two patients who were hospitalized for acute cervical injuries, seventy five lived, seven died within 5 months of injury, and one was lost to follow-up. These patients were grouped by injury mechanism, level of vertebral injury, level and type of cord injury, and management. Degree of injuries and prognosis were classified by modified Frankel's classification. The ratio of male to female was 3.3 to 1. The causes of traumas were traffic accidents, falling down, sports, diving, slip down. Traffic accident was the most common cause of trauma, and passenger injury was the most frequent cause among that. The most common level of dislocation was C5-6 followed by C4-5 level. The C5 vertebra was most commonly fractured. Injury mechanisms divided into 4 groups(compressive or disruptive flexion, compressive or disruptive extenstion. Disruptive extension was less common than other three groups. Vertebral fractures were more common in flexion mechanism than in the extension mechanism. Cord injuries were more common in the compressive injury groups than disruptive one. Spinal cord was frequently injured by compressive flexion mechanism(p<0.005). Complete cord injury was the most common type of cord injury. And complete cord injuries were most frequently ocured by compressive flexion mechanism(p<0.005). On the other hand, forty one cases of asymtomatic spinal column injuries were frequently seen in disruptive flexion mechanism group(p<0.005). Of twenty four patients were operated, forty one were fused posteriorly, one anteriorly, one was performed discectomy, and one was fused anteriorly and posteriorly. Operations were more frequently applied in the compressive mechanism groups(p<0.005). The rate of neurologic improvement was 76.2%, 91.3%, 73.9% and 75% in compressive flexion, disruptive flexion, compressive extension and disruptive extension group respectively. The rate of neurological improvement in the operated group was 83.3%, and 73.7% in the non-operated group. Common complications were urinary tract infection, pneumonia, bed sore, gastrointestinal bleeding. The more frequent complications were urinary tract infection and pneumonia. The rate of complications was more common when the initial neurologic status was worse(p<0.005). Expire rate was high in the compressive flexion mechanism group. When the initial neurologic statue was A, when cord injury was at C6 or higher levels. The most common cause of was pulmonary problem.
Accidents, Traffic ; Classification ; Diskectomy ; Dislocations ; Diving ; Female ; Hand ; Hemorrhage ; Humans ; Lost to Follow-Up ; Male ; Pneumonia ; Pressure Ulcer ; Prognosis ; Spinal Cord ; Spine* ; Sports ; Urinary Tract Infections

Experimental subarachnoid hemorrhage(SAH) was produced in adult cats by injection of autologous blood(6ml) into prepontine cistern by tranclival approach and cisterna magna. The animals were sacrificed 1, 3, 5, 7 or 14 days later and basilar artery segments were prepared for electron microscopy. The following observations were made: 1) 1 to 7 days after SAH, electron micrograph showed round-shaped endothelial cells in tunica intima and disappearance of zonular occludens. Endothelial detachment from internal elastic membrane and intracytoplasmic vacuolation of endothelial cells as well as destruction of mitochondrial cirstae in tunica media. 2) 14 days after SAH, electron micrograph showed the normal findings in tunica intima and tunica media of the vessel walls. On the basis of the above findings, I found that the ultrastructural changes in the basilar arterial wall, which had presumably developed as a consequence of experimental SAH were reversible.
Adult ; Animals ; Basilar Artery* ; Cats ; Cisterna Magna ; Endothelial Cells ; Humans ; Membranes ; Microscopy, Electron ; Subarachnoid Hemorrhage* ; Tunica Intima ; Tunica Media