1.A Case of Epidural Abscess in Middle Cranial Fossa Secondary to Acute Sphenoid Sinusitis.
Jin YU ; Nam Gol KIM ; Wee Hwang KIM ; Won Sang SON
Journal of Rhinology 2006;13(1):60-65
Acute or chronic sinusitis is common disease of ENT. Most cases usually respond to appropriate treatment; however, some cases occasionally progress to the development of serious complication and poor prognosis. The orbital complications are most common complication fallowed by intracranial complications. The incidence of sinogenic intracranial complications is about 3.7-11.0% and these complications are progressively decreasing however the complications occur due to incorrect use of antibiotics, antibiotics resistant pathogens, decreasing host immunity, improper diagnosis and delayed surgical treatment. Therefore the case of epidural abscess in anterior portion of middle cranial fossa secondary to acute sphenoid sinusitis, which was treated with transnasal endoscopic sphenoidotomy and intravenous antibiotics, is being reported.
Anti-Bacterial Agents
;
Cranial Fossa, Middle*
;
Diagnosis
;
Epidural Abscess*
;
Incidence
;
Orbit
;
Prognosis
;
Sinusitis
;
Sphenoid Sinus*
;
Sphenoid Sinusitis*
2.A Case of Cavernous Hemangioma Originated from the Middle Turbinate.
Ki Hun HAN ; Nam Gol KIM ; Wee Hwang KIM ; Won Sang SON
Korean Journal of Otolaryngology - Head and Neck Surgery 2005;48(7):940-942
Hemangiomas are common benign soft tissue tumors in the head and neck, but they occur infrequently in the sinonasal cavity. Most of nasal hemangiomas arise from the nasal septum or vestibule and are of capillary type. Only a few arise from the lateral wall of the nose, and these usually are cavernous. Chief symptoms are recurrent epistaxis and nasal obstruction; if the tumor becomes large, it may cause adjacent bony erosion. Cavernous hemangioma shows essentially little tendency to regress, and in adults, it is more common than capillary hemangioma. Consequently, the majority of cavernous hemangiomas require surgery in contrast to their capillary counterparts. We report a case of cavernous hemangioma of middle turbinate in an adult female, together with a review of the literature.
Adult
;
Capillaries
;
Epistaxis
;
Female
;
Head
;
Hemangioma
;
Hemangioma, Capillary
;
Hemangioma, Cavernous*
;
Humans
;
Nasal Obstruction
;
Nasal Septum
;
Neck
;
Nose
;
Turbinates*
3.A Case of C1 Inhibitor Deficiency Syndrome.
Wee Hwang KIM ; Young Soo PAHN ; Nam Gol KIM ; Ki Joon OH
Korean Journal of Otolaryngology - Head and Neck Surgery 2002;45(2):191-194
C1 inhibitor (C1 INH) deficiency is characterized by recurrent attacks of angioedema. The disorder may be inherited or acquired, with both types presenting a similar phenotypic picture. The angioedema most frequently affects the extremities, gastrointestinal, genital, facial and, airway swelling. The laryngeal angioedema can compromise the integrity of the upper airway, so its early diagonsis is crucial. Acquired angioedema by C1 deficiency is a rare disorder characterized by adult onset and lack of inheritance of the disease. We experienced a case of angioedema in a 37-year old man. He had no family history of angioedema and laboratory data showed depressed C1 inhibitor levels. With a review of literature, authors report a case of acquired angioedema by C1 inhibitor deficiency who had a history of the recurrent swelling of tongue, lip and, oral buccal mucosa.
Adult
;
Angioedema
;
Angioedemas, Hereditary*
;
Extremities
;
Humans
;
Lip
;
Mouth Mucosa
;
Tongue
;
Wills
4.Fine Needle Aspiration Biopsy and Histopathologic Diagnosis in the Head and Neck Mass.
Soon Ho LEE ; Hee Wan PARK ; Chan Youn PARK ; Byung Cheol PARK ; Nam Gol KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1999;42(11):1429-1434
BACKGROUND AND OBJECTIVES: Fine needle aspiration cytology (FNAC) is a safe and economical biospy technique which is widely applicable to palpable masses as a first-line procedure. Successful FNAC, however, demands high specimen quality and experience on the part of both the aspirator and the pathologist. We compared cytological diagnosis with histopathological diagnosis in the head and neck region, in order to increase accuracy and solve any discrepancy in the two types of diagnoses. MATERIALS AND METHODS: From July 1996 through to July 1998, FNAC were carried out in 830 cases in palpable mass of the head and neck region in the Department of Pathology, Chonnam University Hospital. The major target sites were lymph nodes (61.4%), soft tissues (22.2%), and salivary glands (16.4%). Histopathological diagnoses were performed in 267 cases by surgical methods. Cytological reports were classified into the following diagnostic categories: non-tumor, tumor (benign, malignant: primary or metastatic). RESULTS: In a series of 267 cases, there were 70 non-tumor lesions (26.2%), 197 tumor lesions (73.8%), (benign: 77, malignant: 120). Lymph nodes were the most common anatomic sites for FNAC. The overall diagnostic accuracy, sensitivity and specificity of FNAC were 95.5%, 98.8%, and 94.2% allowed an correct diagnosis between FNAC and histopathology. CONCLUSION: FNAC of the head and neck region is a sensitive and specific diagnostic tool, especially when diagnosing metastatic carcinomas. Four major causes of error were identified: material adequacy criteria, sampling technique, cytological interpretation and limitations in the procedure. In particular, attention must be paid to subtle morphological changes when making detailed clinical pathological observations; this may help avoid discrepancies and achieve the right diagnosis.
Biopsy*
;
Biopsy, Fine-Needle*
;
Cytological Techniques
;
Diagnosis*
;
Head*
;
Jeollanam-do
;
Lymph Nodes
;
Neck*
;
Pathology
;
Salivary Glands
;
Sensitivity and Specificity
5.A Case Report of Correction of Cryptotia.
Byung Cheol PARK ; Kwang Ryun KO ; Soon Ho LEE ; Nam Gol KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 2000;43(11):1247-1250
Cryptotia is a congenital auricular anomaly found more commonly in orientals than whites. It is characterizaed by the invagination of the upper part of the auricle under the temporal skin and deformity of the auricular cartilage. Surgeries to correct cryptotia principally involves addition of skin to the deficient retroauricular sulcus and cartilage plasty. We have developed a surgical method using modified retroauricular flap and have obtained good result without complication. We hereby report a surgical case with discussion and review of literatures.
Cartilage
;
Congenital Abnormalities
;
Ear Cartilage
;
Skin
6.Tumor Necrosis Factor-alpha and Apoptosis Following Spinal Nerve Ligation Injury in Rats.
Sung Hoon KIM ; Jae Sik NAM ; Dae Kee CHOI ; Won Wook KOH ; Jeong Hun SUH ; Jun Gol SONG ; Jin Woo SHIN ; Jeong Gil LEEM
The Korean Journal of Pain 2011;24(4):185-190
BACKGROUND: Spinal nerve ligation (SNL) injury in rats produces a pain syndrome that includes mechanical and thermal allodynia. Previous studies have indicated that proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) play an important role in peripheral mediation of neuropathic pain, and that altered dorsal root ganglion (DRG) function and degree of DRG neuronal apoptosis are associated with spinal nerve injury. The present study was conducted to evaluate the expression of TNF-alpha and the extent of apoptosis in the dorsal root ganglion after SNL in rats. METHODS: Sprague-Dawley rats were subjected to SNL of the left L5 and L6 spinal nerves distal to the DRG and proximal to the formation of the sciatic nerve. At postoperative day 8, TNF-alpha protein levels in the L5-6 DRG were compared between SNL and naive groups using ELISA. In addition, we compared the percentage of neurons injured in the DRG using immunostaining for apoptosis and localization of activated caspase-3. RESULTS: SNL injury produced significant mechanical and cold allodynia throughout the 7-day experimental period. TNF-alpha protein levels were increased in the DRG in rats that had undergone SNL (12.7 +/- 3.2 pg/100 microg, P < 0.001) when compared with naive rats (4.1 +/- 1.4 pg/100 microg). The percentage of neurons or satellite cells co-localized with activated caspase-3 were also significantly higher in rats with SNL than in naive rats (P < 0.001, P < 0.05, respectively). CONCLUSIONS: SNL injury produces mechanical and cold allodynia, as well as TNF-alpha elevation and apoptosis in the DRG.
Animals
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Apoptosis
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Caspase 3
;
Cold Temperature
;
Cytokines
;
Diagnosis-Related Groups
;
Enzyme-Linked Immunosorbent Assay
;
Ganglia, Spinal
;
Hyperalgesia
;
Ligation
;
Negotiating
;
Neuralgia
;
Neurons
;
Rats
;
Rats, Sprague-Dawley
;
Sciatic Nerve
;
Spinal Nerves
;
Tumor Necrosis Factor-alpha