1.A Clinical Study of Eudyna in Acne Vulgaris.
Tae Joong NAM ; Kee Chan MOON ; Cheol Heon LEE ; Won Suk KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1977;15(4):423-430
No abstract available.
Acne Vulgaris*
2.A case of Primary Serous Papillary Carcinoma of the Peritoneum..
Moon Cheol PARK ; Jong Ho SHIN ; Jong Min LEE ; Young Yuk KIM ; Chan Yong PARK ; Sang Ik NAM ; Hyuni CHO
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(2):190-193
Although the peritoneum is rare site for a primary neoplasm, certain malignant neoplasms may arise from it. A case of 63-year-old woman who had a serous papillary carcinoma of peritoneal origin is reported. Extraovarian peritoneal serous papillary carcinoma was characterized by ascites, malignant washings, and omental involvement with bulky infiltration and/or multiple tumor nodules. The symptoms caused by diffuse spreading of the neoplasm over the peritoneum are the most important manifestation for clinical diagnosis of malignant primary neoplasm of peritoneum, especially serous papillary carcinoma. This behaving tumor was at least partially responded to therapy. In this report, we describe a case of serous papillary carcinoma of peritoneum carring on proper management with brief review.
Ascites
;
Carcinoma, Papillary*
;
Diagnosis
;
Female
;
Humans
;
Middle Aged
;
Peritoneum*
3.3C8, a new monoclonal antibody directed against a follicular dendritic cell line, HK.
In Yong LEE ; Joon Hee LEE ; Weon Seo PARK ; Eui Cheol NAM ; Yung Oh SHIN ; Jong Seon CHOE
Immune Network 2001;1(1):26-31
BACKGROUND: Follicular dendritic cells (FDCs) play key roles during T cell-dependent humoral immune responses by allowing antigen-specific B cells to survive, proliferate, and differentiate within the FDC networks of secondary follicles, i.e., germinal centers (GC). METHODS: A novel monoclonal antibody, 3C8, was generated by immunizing with an FDC line HK, in order to understand the molecular signals involved in the FDC-B cell interactions in the microenvironment of the GC. RESULTS: The 3C8 antibody did not bind to mononuclear cells, including T cells, B cells, and monocytes. Murine L929 and human skin fibroblasts exhibited no or little reactivity to 3C8. However, 3C8 specifically recognized HK cells by flowcytometry. Furthermore, the antigen recognized by 3C8 was restricted to the GC of the human tonsil. Dendritic networks of the GC were intensely stained by 3C8, but cells out side the GC were not. CONCLUSION: Our result s suggest that the antigen 3C8 may play some unique role on FDCs during the GC reactions.
B-Lymphocytes
;
Cell Communication
;
Dendritic Cells, Follicular*
;
Fibroblasts
;
Germinal Center
;
Humans
;
Immunity, Humoral
;
Monocytes
;
Palatine Tonsil
;
Skin
;
T-Lymphocytes
4.Socioeconomic Status and Successful Delivery after an Infertility Diagnosis:a Nationwide Health Insurance Cohort Study in Korea Conducted from 2005to 2013
Jaeyong SHIN ; Sang Gyu LEE ; Eun-Cheol PARK ; Jin Young NAM
Journal of Korean Medical Science 2020;35(39):e341-
Background:
The global disease burden of infertility is rising and accessibility to infertility treatments and assisted reproduction is a challenging issue. Therefore, we investigated characteristics of successful delivery after an infertility diagnosis among infertile women.
Methods:
We designed a retrospective cohort study with the main outcome measure of a delivery medical record after the initial diagnosis of infertility. A total of 10,108 women patients who were diagnosed with infertility between 2005 to 2013 in the National Health Insurance Cooperation Cohort Database of Korea were enrolled. The adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for subsequent delivery were estimated by applying a Cox proportional-hazard regression model.
Results:
Approximately 55% of infertile women who reported infertility had a delivery eventually. Infertile women who are aged between 30 to 39 (HR, 0.80; 95% CI, 0.75–0.84), in low income level (HR, 0.77; 95% CI, 0.71–0.84), or diagnosed with diabetes (HR, 0.76; 95% CI, 0.60–0.96) were less likely to report a delivery.
Conclusion
These findings highlight demographic, socioeconomic, and medical characteristics of reporting a consequent delivery. Although many previous articles reported an association between socioeconomic status and receiving medical evaluation, there were few studies regarding successful delivery after an infertility diagnosis across socioeconomic status. Thus, the maintaining of support for low socioeconomic status infertile women and their family should be considered after the infertility diagnosis in aspects of financial and social approaches.
5.The Usefulness of the Transabdominal Ultrasonography as a Screening Examination in the Evaluation of the Patient with Suspicious Gastric Disease.
Hyun Cheol KIM ; Hyeong Cheol SHIN ; Hyung Hwan KIM ; Seong Jin PARK ; Deok Ho NAM ; Won Kyung BAE ; Il Young KIM ; Du Shin JEONG ; Il Kwun CHUNG
Journal of the Korean Society of Medical Ultrasound 2005;24(1):23-29
PURPOSE: To evaluate the usefulness of transabdominal ultrasonography as a screening examination in patients with suspicious gastric disease. MATERIALS AND METHODS: We selected 141 patients with epigastric pain and who were found to have antral gastric wall thickening of more than 5 mm in transabdominal ultrasonography, and who underwent gastroscopy immediately following the ultrasonography examination, because we suspected that these patients had gastric disease. We measured the full thickness of the five layers of the gastric wall and evaluated the preservation of this fivelayered structure. We respectively compared the gastric wall thickness and the preservation of gastric layers in 26 normal, 91 gastritis, 12 gastric ulcer, and 12 gastric cancer patients, who were classified based on the gastroscopy results. RESULTS: The mean thicknesses of the gastric wall in the normal, gastritis, gastric ulcer and gastric cancer patients were 5.13+/-0.14 mm, 6.71+/-1.33 mm, 8.08+/-2.80 mm, and 12.45+/-3.70 mm, respectively. The gastric walls in the gastritis, gastric ulcer and gastric cancer patients were significantly thicker than that in the normal patients (p < 0.01). The gastric wall in the gastric cancer patients was significantly thicker than those in the gastritis and gastric ulcer patients (p < 0.01). However, the difference in the gastric wall thickness between the gastritis and gastric ulcer patients was not statistically significant (p >0.01). Except for two patients with gastritis and three patients with gastric ulcer, the stratification of the gastric wall was preserved in all of the normal, gastritis and gastric ulcer patients, whereas it was disrupted in all of the patients with gastric cancer. CONCLUSION: Transabdominal ultrasonography in the fasting state may be a helpful and convenient modality, which can serve as a screening examination in the evaluation of gastric disease. Therefore, careful attention and effort are needed to evaluate the gastric wall during transabdominal ultrasonography.
Fasting
;
Gastritis
;
Gastroscopy
;
Humans
;
Mass Screening*
;
Peptic Ulcer
;
Stomach Diseases*
;
Stomach Neoplasms
;
Stomach Ulcer
;
Ultrasonography*
6.Angiomyolipoma of the Perinephric Space: Case Report.
Ho Seob SHIN ; Seong Kuk YOON ; Jin Hwa LEE ; Chan Sung KIM ; Jong Young OH ; Tae Beom SHIN ; Ki Nam LEE ; Kyung Jin NAM ; Dae Cheol KIM
Journal of the Korean Radiological Society 2002;47(6):647-650
Angiomyolipomas commonly originate from renal parenchyma but extremely rarely from perinephric space. We report a case of angiomyolipoma of the perinephric space confirmed by radical nephrectomy. A 13-year-old boy presented with left flank pain and abdominal distension, first experienced five months earlier. Ultrasonography and CT indicated that in the space surrounding the left kidney, a huge fat-containing mass with linear strands was present.
Adolescent
;
Angiomyolipoma*
;
Flank Pain
;
Humans
;
Kidney
;
Male
;
Nephrectomy
;
Ultrasonography
7.Effect of Volume on Hypobaric Spinal Anesthesia for Perianal Surgery with Prone Jacknife Position .
Yang Sik SHIN ; Kyoung Min LEE ; Hyo Keun LEE ; Jong Rae KIM ; Sung Cheol NAM
Korean Journal of Anesthesiology 1991;24(4):760-763
The effect of anesthetic volume on the spread of hypobaric tetracaine were sutdied after intrathecal injection in thirty patients with prone jackknife and 15 degree Trendelenburg position for perinal surgery. The patients were assigned randomly into the one of three groups divided by the 3, 4, or 5 ml of volume of anesthetic solution. The results show that the volume of tetracaine in distilled water with hypobaric spinal anesthesia in prone jackknife and l5 degree Trendelenburg position had a important effect on the anesthetic dermatomal levels in spite of slightly rapid onset with large. volume. Therefore, we concluded that for the perianal surgery in prone jackknife position, as the volume of the anes- thetic solution with hypobaric spinal anesthesia, 3 or 4 ml of the volume are sufficient to get the adequate anesthetic levels.
Anesthesia, Spinal*
;
Head-Down Tilt
;
Humans
;
Injections, Spinal
;
Tetracaine
;
Water
8.Intracerebral Hemorrhage and HELLP Syndrome in Eclampsia: A Case Report.
Jae Ju LEE ; Kyun HAN ; Hyun Sung LEE ; Cheol Hong PARK ; Shin Woo NAM
Korean Journal of Obstetrics and Gynecology 2003;46(2):440-445
Eclampsia is defined as the occurrence of convulsions, not caused by any coincidental neurologic disease such as epilepsy, in a woman whose condition also meets the criteria for preeclampsia. Intracerebral hemorrhage with eclampsia is rare but maternal mortality is 30-40%. Fetal outcome parallels that of the mother and reflects the maternal condition as well as gestational age at delivery. With noninvasive imaging technique of CT, the early diagnosis and proper management of intracerebral hemorrhage in a patient can be achieved. The syndrome of Hemolysis, Elevated Liver enzyme, Low Platelets (HELLP) is considered to be complication of severe preeclampsia-eclampsia. We report a case of intracerebral hemorrhage and HELLP syndrome in a patient with eclampsia.
Cerebral Hemorrhage*
;
Early Diagnosis
;
Eclampsia*
;
Epilepsy
;
Female
;
Gestational Age
;
HELLP Syndrome*
;
Hemolysis
;
Humans
;
Liver
;
Maternal Mortality
;
Mothers
;
Pre-Eclampsia
;
Pregnancy
;
Seizures
9.Bronchospasm during the Maintenance of General Anesthesia: A case report.
Sae Cheol OH ; Youn Suk SON ; Shin Woo NAM ; Keon Jung YOON
Korean Journal of Anesthesiology 2005;49(4):532-537
Although a bronchospastic attack is common during the induction and emergence of general anesthesia, it is quite rare during maintenance of it. We experienced a severe case of a bronchospasm in a male patient during the maintenance of general anesthesia. His past medical history indicated no risk factors for the bronchospasm except for heavy smoking. He suffered from poor ventilation, hypercarbia and a pneumothorax that occurred abruptly, 2 hours after inducing general anesthesia. Ten hours later, he recovered his normal respiratory function without any respiratory complication. This case highlights the possibility of a bronchospasm during the maintenance of general anesthesia.
Anesthesia, General*
;
Bronchial Spasm*
;
Humans
;
Male
;
Pneumothorax
;
Risk Factors
;
Smoke
;
Smoking
;
Ventilation
10.Therapeutic Effect of Rebamipide in Infertile Men with Oxidative Stress.
Dong Gil SHIN ; Geom Su OH ; Nam Cheol PARK
Korean Journal of Urology 2004;45(4):346-353
PURPOSE: This study was performed to investigate whether rebamipide is useful in the treatment of male infertility due to oxidative damage. MATERIALS AND METHODS: 50 infertile males with elevated reactive oxygen species (ROS) in their semen were enrolled. All patients were given an oral daily dose of 900mg rebamipide for at least 3 months. The concentrations of rebamipide and ROS, and the levels of lipid peroxidation, sperm motility, vitality and fertilizing capacity were measured by a high-performance liquid chromatography (HPLC) fluorescent method, chemiluminescence, the thiobarbituric acid method, a computer assisted semen analyzer, eosin-nigrosin staining and hypo-osmotic swelling test, respectively. Additionally, the clinical outcomes, including pregnancy and delivery, were observed at the gynecology outpatient and IVF clinics. RESULTS: The rebamipide concentration in semen after medication was 220.77+/-327.84ng/ml (SD), with a large deviation, but this was higher than the level found in the serum, which was 126+/-76ng/ml (SD). The levels of seminal ROS and lipid peroxidation were significantly decreased according to the duration of treatment (p<0.05). The sperm vitality and fertilizing capacity were also significantly improved at 2-3 months post treatment (p<0.05). Out of the 41 cases with trial pregnancies, 20 (48.8%) became pregnant, consisting of childbirth, miscarriage or ongoing in 17, 2 and 1 case, respectively. Side effects were observed in only 1 case (2%) with self-limits. CONCLUSIONS: These results suggest that rebamipide is an effective free radical scavenger, which may be useful as an oral antioxidant in patients with male infertility due to oxidative damage caused by high tissue affinity to the male accessory organ, antioxidant effect and the improving effect of seminal parameters.
Abortion, Spontaneous
;
Antioxidants
;
Chromatography, Liquid
;
Female
;
Gynecology
;
Humans
;
Infertility, Male
;
Lipid Peroxidation
;
Luminescence
;
Male
;
Outpatients
;
Oxidative Stress*
;
Parturition
;
Pregnancy
;
Reactive Oxygen Species
;
Semen
;
Sperm Motility
;
Spermatozoa