1.Tensile Strength of Musculoscleral Insertion after Superior Rectus Recession on Rabbit.
Dong Ho PARK ; Nak Hong JUNG ; Jae Pil SHIN ; Jung Yoon KWON
Journal of the Korean Ophthalmological Society 2004;45(4):675-680
PURPOSE: The author performed this experimental study to investigate the changes in the tensile strength of a new insertion following a superior rectus recession in a rabbit's eye. METHODS: Conventional superior rectus muscle recession procedures with the hang-back suture technique were performed on New Zealand white rabbits (body weight 2~3kg), after which the disinsertional force was measured using a digital tension gauge on the 3rd, 5th, and 7th days, and then weekly for up to 8 weeks postoperatively. RESULTS: The postoperative disinsertional forces were as follows: 38.25 +/- 2.75, 165 +/- 31.27, and 167.25 +/- 26.99 g at the 3rd , 5th and 7th days, and 211.00 +/- 25.66, 222.75 +/- 26.66, 255.25 +/- 24.51, 271.50 +/- 38.25, 429.50 +/- 21.14 g at the 2nd, 3rd, 4th, 6th and 8th weeks respectively. The disinsertional forces linearly increased with the postoperative time period and there was a strong correlation with correlation coefficient being 0.903. CONCLUSIONS: We concluded that musculoscleral adhesion with hang-back suture maintained enough strength in early postoperative time period.
Rabbits
;
Suture Techniques
;
Sutures
;
Tensile Strength*
2.Gastric Necrosis after Gastric Dilatation in a Patient with Bulimia.
Nak Eun CHUNG ; Han Young LEE ; Min Jung KIM ; You Jin WON ; Tae Jung KWON
Korean Journal of Legal Medicine 2011;35(2):165-168
Acute gastric dilatation leading to gastric necrosis is rare but potentially fatal condition that can occur in patients with bulimia. It usually develops after a bulimic episode and it is not diagnosed with sufficient rapidity it may lead to gastric perforation followed by peritonitis, sepsis, shock, and death. Because of the rarity of this condition and the patients in whom it occurs, the clinician must maintain a high degree of suspicion when treating patients with eating disorders who present with abdominal pain after a binge. This case report describes a 24-year old woman with acute gastric dilatation due to binge eating, who had the gastrotomy and died of complications such as gastric necrosis and disseminated intravascular coagulation.
Abdominal Pain
;
Bulimia
;
Disseminated Intravascular Coagulation
;
Feeding and Eating Disorders
;
Female
;
Gastric Dilatation
;
Humans
;
Necrosis
;
Peritonitis
;
Sepsis
;
Shock
3.Artery to Collecting System Communication after Abdominal Trauma.
Chang Ug LEE ; O Jung KWON ; Sung Hak BANG ; Nak Young CHOI ; Chang Sub LEE ; Seung Hyun AHN
Journal of the Korean Society of Traumatology 2006;19(2):192-195
Degenerative vascular disease, previous arterial surgery, long-term ureteral stenting, pelvis surgery, and radiotheraphy are reported as causes of artery-to-collecting-system communication.. Artery-to-collecting-system- communication associated with blunt trauma is rare, but potentially fatal. The diagnosis is very difficult and requires a high degree of suspicion. We were able to make the diagnosis based on the characteristic finding of contrast-enhanced computed tomography (CT) obtained in the early phase, equivalent to the finding obtained in the corticomedullary phase of the kidney. We report a case of artery to collecting system communication due to blunt abdominal trauma following a fall, which was treated by embolization.
Arteries*
;
Diagnosis
;
Kidney
;
Pelvis
;
Stents
;
Ureter
;
Vascular Diseases
4.Artery to Collecting System Communication after Abdominal Trauma.
Chang Ug LEE ; O Jung KWON ; Sung Hak BANG ; Nak Young CHOI ; Chang Sub LEE ; Seung Hyun AHN
Journal of the Korean Society of Traumatology 2006;19(2):192-195
Degenerative vascular disease, previous arterial surgery, long-term ureteral stenting, pelvis surgery, and radiotheraphy are reported as causes of artery-to-collecting-system communication.. Artery-to-collecting-system- communication associated with blunt trauma is rare, but potentially fatal. The diagnosis is very difficult and requires a high degree of suspicion. We were able to make the diagnosis based on the characteristic finding of contrast-enhanced computed tomography (CT) obtained in the early phase, equivalent to the finding obtained in the corticomedullary phase of the kidney. We report a case of artery to collecting system communication due to blunt abdominal trauma following a fall, which was treated by embolization.
Arteries*
;
Diagnosis
;
Kidney
;
Pelvis
;
Stents
;
Ureter
;
Vascular Diseases
5.Post-traumatic primary bacterial peritonitis.
Kyung Moo YANG ; Nak Eun JUNG ; Jae Kwon KIM ; Shin Mong KANG
Korean Journal of Legal Medicine 2007;31(2):185-187
Spontaneous bacterial peritonitis (SBP) is a bacterial infection of ascites arising from liver cirrhosis, nephrotic syndrome and so on. Primary bacterial peritonitis (PBP) is a rare intraabdomial infection in the absence of underlying diseases or rupture of the viscus. The authors report an autopsy case of posttraumatic primary bacterial peritonitis in the otherwise physically healthy young female. She was beaten repeatedly around the abdomen with human physical instruments for a prolonged time.
Abdomen
;
Ascites
;
Autopsy
;
Bacterial Infections
;
Female
;
Humans
;
Liver Cirrhosis
;
Nephrotic Syndrome
;
Peritonitis*
;
Rupture
6.Age-related Alterations of Normal Ascending Aorta among Koreans with Special Reference to Cystic Medial Necrosis.
Tae Jung KWON ; Dong Hwan SHIN ; Kyung Moo YANG ; Nak Eun CHUNG
Korean Journal of Pathology 2002;36(5):281-285
BACKGROUND: The specificity of aortic alteration in the pathogenesis of aortic dissection has been challenged. To obtain comprehensive morphologic data that may enhance the appreciation of the pathogenesis of aortic disease in normal aorta among Koreans, we performed a morphologic study of aorta with aging. METHODS: The histologic and morphometric studies of ascending aorta without cardiovascular disease were carried out on seventy-two autopsy cases. Alcian blue-stained sections were subjected to morphometric study using image analysis system. The age range of the cases was from newborn to those who had been in their eighties. RESULTS: The most prominent feature of aging aorta was fragmentation and loss of elastic lamellae, and expansion of interlamellar spaces. Cystic medial necrosis of varying degrees was observed in almost every specimen. On the morphometric study, the percentage area of mucoid degeneration revealed no statistically significant differences among the varying age groups. Compared to males, female subjects exhibited significant mucoid degeneration (p<0.05). CONCLUSIONS: The alteration of elastic lamellae is increased with age. Cystic medial necrosis is not considered merely an aging phenomenon, but is enhanced in the aorta of females.
Age Factors
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Aging
;
Aorta*
;
Aortic Diseases
;
Autopsy
;
Cardiovascular Diseases
;
Female
;
Humans
;
Infant, Newborn
;
Male
;
Necrosis*
;
Pathology
;
Sensitivity and Specificity
7.Sudden death due to epiglottic abscess.
Kyung Moo YANG ; Nak Eun JUNG ; Jae Kwon KIM ; Shin Mong KANG
Korean Journal of Legal Medicine 2007;31(1):89-91
Acute epiglottitis is a local bacterial infection of the supraglottic area. Epiglottitis is generally caused by organisms which invoke an inflammatory response that develops rapid obstructive edema. The disease rarely progresses to abscess stage, either because medical intervention is sought or death by asphyxiation ensues. A 38-year-old, mentally ill but physically healthy woman died of airway obstruction caused by acute epiglottitis forming an abscess. She died unexpectedly and suddenly showing only minor nonspecific symptoms.
Abscess*
;
Adult
;
Airway Obstruction
;
Bacterial Infections
;
Death, Sudden*
;
Edema
;
Epiglottitis
;
Female
;
Humans
;
Mentally Ill Persons
8.Fatal Hemophagocytic Syndrome : Three Autopsy Cases.
Yi Suk KIM ; Tae Jung KWON ; Nak Eun CHUNG ; Young Shik CHOI
Korean Journal of Legal Medicine 2005;29(1):79-83
Hemophagocytic Syndrome (HS) is a systemic lymphohistiocytic proliferative disorder associated with infection or malignancies, particularly Epstein-Barr virus (EBV) HS is presented with high fever, skin rash, hepatosplenomegaly, and cytopenia. The characteristic pathologic finding is massive lymphohistiocytic infiltration with hemophagocytosis in various organs including bone marrow, liver, and spleen. Hyperproduction of cytokines by activated T lymphocytes has been presumed to account for the hemophagocytosis and clinical manifestations of HS. We report three childhood autopsy cases with HS which was confirmed by histopathologic examination. According to medical records, all cases had high fever with or without skin rash, cytopenia, AST/ALT elevation, and hyperfibrinogenemia, and showed multiple organ failure eventually. At autopsy, there were no specific gross findings except splenomegaly, but extensive lymphohistiocytic infiltration with hemophagocytosis was seen in various organs including lymph nodes, spleen, liver, and bone marrow. In one of three cases, EBV was identified with in situ hybridization method. As this disease has rapidly progressive clinical course with fatal outcome during childhood, so the possibility of HS should be considered in children presenting with high fever and hepatosplenomegaly.
Autopsy*
;
Bone Marrow
;
Child
;
Cytokines
;
Exanthema
;
Fatal Outcome
;
Fever
;
Herpesvirus 4, Human
;
Humans
;
In Situ Hybridization
;
Liver
;
Lymph Nodes
;
Lymphohistiocytosis, Hemophagocytic*
;
Medical Records
;
Multiple Organ Failure
;
Spleen
;
Splenomegaly
;
T-Lymphocytes
9.Morphologic Study on Coronary Artery of Korean.
Sang Yong LEE ; Tae Jung KWON ; Nak Eun CHUNG ; Joong Seok SEO ; Han Young LEE ; Won Tae LEE
Korean Journal of Legal Medicine 2002;26(1):7-16
Measurements of the diameter of the coronary artery (left main, left anterior descending branch, left circumflex branch, right) and the length of the coronary artery (left main, left anterior descending) were performed in 77 cases obtained from corpses with normal and mild atherosclerosis of coronary artery. Fifty-six males and 21 females were studied whose ages ranged from 15 -78 years old. The diameter of the coronary artery exponentially increased in accordance with the increase of age (left main coronary artery: lumen diameter=1.847+0.216 X age, R2=0.632, p<0.01; left anterior descending branch: lumen diameter=1.513 +0.241 X age, R2=0.539, p<0.01; right coronary artery:lumen diameter=1.830 +0.193 X age, R2=0.513, p<0.01; left circumflex branch: lumen diame-ter= 1.470+0.159 X age, R2=0.502, p<0.01). The lumen diameter of the left main coronary artery, the length of the left anterior descending branch and the thickness of the left anterior descending branch exponentially increased in accordance with the increase of the heart weight(left main coronary artery: lumen diameter=1.721+0.031 X heart weight, R2=0.338, p<0.01; left anterior descending branch: length=7.114+0.103 X heart weight, R2=0.313, p<0.01; left anterior descending branch: wall thickness=0.226+0.009 X heart weight, R2=0.256, p<0.01). But no significant difference was observed between the diameter, length of the coronary artery and various body indices, and heart weight. Microscopic and immunohistochemical studies on coronary arteries of 77 cases showed high frequency of diffuse intimal thickening with many smooth muscle cells and scanty macrophages and fragmentation of internal elastic lamina in arteries without atherosclerosis. These results indicate that the lumen diameter of coronary artery is closely correlated with age but not with various body indices and heart weight, and the length of the anterior descending branch is closely correlated with heart weight but not with age and various body indices. The results of the microscopic and immunohistochemical studies indicate that the early event of the atherosclerosis of the coronary artery is intimal thickening and fragmentation of internal elastic lamina.
Arteries
;
Atherosclerosis
;
Cadaver
;
Coronary Vessels*
;
Female
;
Heart
;
Humans
;
Macrophages
;
Male
;
Myocytes, Smooth Muscle
10.Prevalence of Congenital Coronary Artery Anomalies of Korean Men Detected by Coronary Computed Tomography.
Jae Hyun PARK ; Nak Hyun KWON ; Jun Hwan KIM ; Yu Jin KO ; Seo Hee RYU ; Seok Jin AHN ; Young Jung KIM ; Joo Yeong BAEG ; Jung Im KIM
Korean Circulation Journal 2013;43(1):7-12
BACKGROUND AND OBJECTIVES: It has been demonstrated that the anomalous origin of coronary arteries (AOCA) are generally asymptomatic and rare diseases. However, some cases can cause severe life threatening events. To detect these anomalies, coronary angiographies and autopsies were used to detect coronary artery anomalies, but these procedures have limitations because of their invasiveness. The new device, Multidetector Computed Tomography (MDCT), now replaces the method of choice for detecting coronary anomalies. The prevalence of these anomalies in Korea has not been studied yet. This present analysis attempted to determine the prevalence of AOCA in Korean men by MDCT. SUBJECTS AND METHODS: 1582 Korean male police officers underwent coronary MDCT for their health screening voluntarily. After reconstruction of CT images, we could confirm coronary artery anomalies. RESULTS: The prevalence of AOCA in Korean men was 1.14% (18 out of 1582 cases). The most common abnormality (11 cases, 0.70%) was the origin of the coronary artery. Anomalies of the coronary artery end point were observed in 5 cases (0.32%). The anomalous location of coronary ostium on the aortic root was observed in 1 case (0.06%). An anomalous collateral vessel was observed in 1 case (0.06%). CONCLUSION: The prevalence of coronary artery anomalies in Korean men was 1.14%. Coronary CT is a safe and noninvasive modality for detecting coronary anomalies.
Autopsy
;
Coronary Angiography
;
Coronary Vessel Anomalies
;
Coronary Vessels
;
Humans
;
Korea
;
Male
;
Mass Screening
;
Multidetector Computed Tomography
;
Police
;
Prevalence
;
Rare Diseases