This study was aimed to investigate the effect of Flos Carthami on the atherosclerosis in rabbit induced by cholesterol diet. 24 rabbits were divided by 3 groups; normal control group, CH group, and CH+FC group. The normal control group was fed with the normal pellet diet. The CH group was fed with pellet diet including 4% cholesterol, and the CH+FC group was fed with pellet diet including 4% cholesterol and 4% Flos Carthami dry -extract powder about 100g diet per 1 kg body weight per a day. After 12 weeks, animals were sacrificed and a piece of ascending aorta was collected. Tissue was sectioned 8 micrometer thickness and sections were stained with hematoxylin -eosin, alcian blue pH 2.5, aldehyde -fuchsin, and Van Gieson 's trichrome method. In CH+FC group, atheroma and mucoprotein formation on tunica intima of the ascending aorta was reduced, and lesion of elastic and collagen fibers in tunica media was also attenuated with respect to that in CH group. According to this result, it is considered that Flos Carthami has a preventing effect on atherosclerosis or a control effect on hypercholesterolemia. But distinct mechanism of action is still unclear.
Alcian Blue ; Animals ; Aorta ; Atherosclerosis* ; Body Weight ; Cholesterol* ; Collagen ; Diet* ; Hematoxylin ; Hydrogen-Ion Concentration ; Hypercholesterolemia ; Plaque, Atherosclerotic ; Rabbits ; Tunica Intima ; Tunica Media

BACKGROUND: Acute abdominal pain is one of the most common problems in the family practice but the differential diagnosis of acute abdominal pain is difficult in first encounter. When family physicians are encountered with patients with acute abdominal pain in the ambulatory care settings, t,hey have to make a decision for management of acute abdominal pain such as admission, referral, discharge or follow-up without any definite diagnosis. If it is possible to predict the course or prognosis of acute abdominal pain by using certain data about patients, it will be helpful to make a decision for the management of acute abdominal pain. So we tested the hypothesis that acute abdominal pain with intermittent pain nature and normal simple abdomen X-ray finding is not serious and shows favorable outcome. METHODS: 126 patients with acute abdorninal pain were enrolled from Feb. to Aug. in 1995 at the emergency department of Kyungju hospital, Dongkuk University. 116 patients showed normal simple abdomen X ray finding and among them 94 patients were discharged and 21 patients were admitted. 92 patients were contacted in 1 week by phone call and they reported the outcome of their acute abdominal pain. RESULTS: Among 92 study populations, 44 patients were male and 48 patients were female. 72 patients complained intermittent abdominal pain and 21 patients complained continous abdominal pain. Frequencies of tentative diagnosis at emergency department were 45 acute gastroenteritis, 26 unknown, 14 functional gastointestinal disorders, 4 acute gastritis, 2 pelvic inflammatory diseases, and 1 ureter stone. Outcomes of patients with intermittent abdominal pain were more favorable than those with continous abdominal pain. CONCLUSIONS: If the patients with acute abdominal pain have intermittent pain nature and normal simple abdomen x ray finding, they will show favorable outcome and can be managed at ambulatory care settings.
Abdomen ; Abdominal Pain ; Ambulatory Care ; Diagnosis ; Diagnosis, Differential ; Emergency Service, Hospital ; Family Practice ; Female ; Follow-Up Studies ; Gastritis ; Gastroenteritis ; Gyeongsangbuk-do ; Humans ; Male ; Pelvic Inflammatory Disease ; Physicians, Family ; Prognosis ; Referral and Consultation ; Ureter

BACKGROUND: There is much harmful influence for health promotion when general publics and medical group misunderstand common health knowledge. Therefore we investigated the proportion of misunderstanding about health knowledge of general publics and medical group. METHODS: The data were collected via questionnaire which consisted of 30 questions (ll health behavior, 5 symptom, 14 treatment knowledge) quoted or revised on the basis of the book ('Misunderstood common health knowledge 100' published by humanism practice medical doctor association, 1994, hanwol company, South korea). The subjects were nonmedical group (third grade elementary school teachers and parents of students in Kyong ju city) and medical group (doctors-specialist, resident, intern, oriental doctor, medical student, nurse, assistant nurse in Kyong-Ju, Pohang city). The score was given 0 for false answer or no answer and 1 for true answer. RESULTS: The dominant subclasses of study subjects were as follows .Sex; female(352:64.5%)/age; 30-40 years old(318 persons : 58.5%) education ; high school graduate group(232: 42.8%)/job; nonmedical group(housewives, 168:36.2%), rnedical group(nurse, 67:36.2%). Medical group acquired higher total average score than non-medical group. There were no differences in the total scores about treatment, symptom, and health behavior in nonmedical group by job. In the medical group, doctors earned significantly higher score than other jobs. The average score per question was 0.53 in nonmedical group and 0.69 in medical group. Non-medical group received average score below 0.5 in 14 questions among 30 questions, while medical group received only in 5 items. CONCLUSIONS: Medical group acquired higher total average score than nonmedical group. Average score per question was 0.53 in non-medical group and 0.69 in medical group.
Education ; Gyeongsangbuk-do ; Health Behavior ; Health Promotion ; Humanism ; Humans ; Parents ; Students, Medical ; Surveys and Questionnaires

BACKGROUND: Acute abdominal pain in children is one of the most common problems encountered in our daily practice. The children often are not able to tell us their exact complain symptoms and differential diagnosis of acute abdominal pain is difficult in its first encounter. When family physicians encounter patients with acute abdominal pain in the ambulatory care settings, they must make an appropriate decision for proper management such as admission, referral, discharge and follow-up without firm diagnosis. If it is possible to predict the course or prognosis of acute abdominal pain by clinical data concerning patient, it will be helpful to make a decision for the management of acute abdominal pain. So we tested for hypothesis that patients with acute intermittent abdominal pain and normal simple abdomen X-ray finding is not serious and shows favorable outcome. METHOD: 82 patients with acute abdominal pain were assessed from Oct. in 1996 to Sep. in 1997 at the emergency department of Kyungju Hospital, Dongkuk University. 69 patients among 82 showed normal simple abdomen X-ray findings. 67 patients were discharged and 2 patients were admitted. 64 patients were contacted by phone call after 1 week and reported their outcome of the previous abdominal pain. RESULTS: Among 64 subjects 36 patients were male and 28 patients female. 57 patients complained of intermittent abdominal pain and 7 patients complained continous abdominal pain. Positive predictive value of intermittent abdominal pain and normal simple abdominal x-ray was 98%. Outcome of patients with intermittent abdominal paln was more favorable than that of continuous pain. CONCLUSIONS: Acute intermittent abdominal pain and normal simple abdomen x-ray findings in children shows favorable outcome and can be managedim ambulatory care settings.
Abdomen ; Abdominal Pain* ; Ambulatory Care ; Child* ; Decision Making* ; Diagnosis ; Diagnosis, Differential ; Emergency Service, Hospital ; Female ; Follow-Up Studies ; Gyeongsangbuk-do ; Humans ; Male ; Physicians, Family ; Prognosis ; Referral and Consultation

BACKGROUND: Hepatitis B vaccination schedule commonly used in Korea is divided largely into 0, 1, 2 month scheduled vaccination group(0, 1, 2 group) and 0, 1, 6 month scheduled vaccination gorup(0, 1, 6 group). The only difference bet.ween two groups is the interval from 2nd dose to 3rd dose. This st,udy had been carried out, to find whether t.he difference of vaccination interval influence the vaccination complet,ion rate or not. METHODS: Study objects are 135 persons over 20 years old who had heptitis B vaccination more than once in injection room of Dongkuk University Kyong-ju Hospital from Jan. 1st in 1996 to Dec. 31th in 1996. Data about vaccination completion were gathered from record book of injection room and telephone interview. RESULTS: Hepatitis B vaccination completion rate is 73.8% in 0, 1, 2 group and 72.5% in 0, 1, 6 group. The reasons for incomplete vaccination are forgetting vaccinat.ion date(36.4% in 0, 1, 2 group and 50% in 0, 1, 6 group), having no time to spare for vaccination(54.5% in 0, 1, 2 group and 43% in 0, 1, 6 group) and knowing positive HBsAb before completion of scheduled vaccination(9.1% in 0, 1, 2 group and 7% in 0, 1, 6 group). CONCLUSIONS: There is no difference in Hepatitis B vaccination complet,ion rate bet.ween 0, 1, 2 group and 0, 1, 6 group.
Appointments and Schedules ; Gyeongsangbuk-do ; Hepatitis B* ; Hepatitis* ; Humans ; Interviews as Topic ; Korea ; Vaccination* ; Young Adult

No abstract available.
Pregnancy*

BACKGROUND: Hepatitis B is an important disease in South Korea because the prevalence is high. There are two officially granted hepatitis B vaccination schedules; 0, 1, 2 month schedule (not 0, 1, 2, 12 month schedule) and 0, 1, 6 month schedule. This study was performed to compare vaccination completion rate between the two schedules. METHODS: The study subjects were all subjects who came to the City Medical Center to receive their first hepatitis vaccination dose from March to September, 1998. On odd numbered day, 0, 1, 2 month schedule was delivered and on even numbered day 0, 1, 6 month schedule was delivered. On the first visit, the data about general characteristics were collected via self administered questionnaire. Whether three vaccination doses were all received or not was ascertained by vaccination registration book. The subjects whose vaccination completion could not be ascertained by the book were called by telephone. The data were analyzed by Excel and SPSSPC. RESULTS: Total collected cases were 822. Among them, 99 cases were excluded from analysis due to reasonable incompletion (11), incorrect inclusion (9) and impossible confirmation (79), which left 723 cases. General characteristics between two groups were not different except the existence of intrafamilial hepatitis carrier. The hepatitis B vaccination completion rate was higher in 0, 1, 2 month schedule (85.4%) than in 0, 1, 6 month schedule (76.1%) only in the cases without intrafamilial hepatitis B carrier member. CONCLUSION: The completion rate of hepatitis B vaccination was higher in 0, 1, 2 month schedule than 0, 1, 6 month schedule in the cases without intrafamilial hepatitis B carrier member.
Appointments and Schedules* ; Compliance ; Financing, Organized ; Hepatitis B* ; Hepatitis* ; Korea ; Prevalence ; Telephone ; Vaccination* ; Surveys and Questionnaires

BACKGROUND: Even though there have been much improvment in general understanding of the climacteric period and increased knowledge of biological aspects of menopause such as Hormone Replacement Therapy, the psychosocial aspects of climacterium was relatively out of consideration. The purpose of this paper is to help make it easy understanding the psychosocial determinants of climacterium through the investigation of correlation between the life stress and the climacteric symptoms in the middle aged women. METHODS: This study was performed on climacteric women at the age ranging from 40 to 55 who reside in Kyong-Ju city. Self reported questionnaires composed of inquiry about demographic characteristics, climacteric symptom scale, and life stress scale were distributed and 123 cases were analyzed in June. and July 1996. The Climacteric Symptom Scale was developed by JG Greene in 1976. In this scale, climacteric symptoms were classified to 3 categories of psychological, somatic, vasomotor symptoms by factor analysis. For quantitative measurement of stress, we used Office Stress Measurement Scale developed by Bae JM et al in 1992. We studied the correlation between stress scores and each class of climacteric symptoms, and the difference of climacteric symptom scores according to the menopausal status and demographic characteristics. RESULTS: The correlation coefficient between the climacteric symptom scores and the stress scores was 0.329(P=0.000) but this correlation was significant in only premenopausal group(correlation coefficient=0.479). Among climacteric symptom classes, the correlation with stress scores is most prominent in psychological symptom class, then somatic symptoms, vasomotor symptoms. There was no difference in climacteric symptom scores to the menopausal status and demographic characteristics. CONCLUSIONS: Women who had more stress complained more climacteric symptoms, especially psychological symptoms. This correlation was significant in the premenopausal group only. And the severity of climacteric symptoms didnt change by demographic characteristics.
Climacteric* ; Female ; Gyeongsangbuk-do ; Hormone Replacement Therapy ; Humans ; Menopause ; Middle Aged ; Self Report ; Stress, Psychological* ; Surveys and Questionnaires

BACKGROUND: Even though there have been much improvment in general understanding of the climacteric period and increased knowledge of biological aspects of menopause such as Hormone Replacement Therapy, the psychosocial aspects of climacterium was relatively out of consideration. The purpose of this paper is to help make it easy understanding the psychosocial determinants of climacterium through the investigation of correlation between the life stress and the climacteric symptoms in the middle aged women. METHODS: This study was performed on climacteric women at the age ranging from 40 to 55 who reside in Kyong-Ju city. Self reported questionnaires composed of inquiry about demographic characteristics, climacteric symptom scale, and life stress scale were distributed and 123 cases were analyzed in June. and July 1996. The Climacteric Symptom Scale was developed by JG Greene in 1976. In this scale, climacteric symptoms were classified to 3 categories of psychological, somatic, vasomotor symptoms by factor analysis. For quantitative measurement of stress, we used Office Stress Measurement Scale developed by Bae JM et al in 1992. We studied the correlation between stress scores and each class of climacteric symptoms, and the difference of climacteric symptom scores according to the menopausal status and demographic characteristics. RESULTS: The correlation coefficient between the climacteric symptom scores and the stress scores was 0.329(P=0.000) but this correlation was significant in only premenopausal group(correlation coefficient=0.479). Among climacteric symptom classes, the correlation with stress scores is most prominent in psychological symptom class, then somatic symptoms, vasomotor symptoms. There was no difference in climacteric symptom scores to the menopausal status and demographic characteristics. CONCLUSIONS: Women who had more stress complained more climacteric symptoms, especially psychological symptoms. This correlation was significant in the premenopausal group only. And the severity of climacteric symptoms didnt change by demographic characteristics.
Climacteric* ; Female ; Gyeongsangbuk-do ; Hormone Replacement Therapy ; Humans ; Menopause ; Middle Aged ; Self Report ; Stress, Psychological* ; Surveys and Questionnaires

BACKGROUND: In women, the prevalence of depression is known to be more than twice as high as in men. Because many depressive women complain of their somatic symptoms instead of neurovegetative ones, many cases of depression have been misdiagnosed. Women also tend to use medicine more frequently than men do to manage depression. So we investigated the relationship between somatic symptoms and drug use in housewives for better management. METHODS: From 1st. March to 31st. March in 1996, the prepared questionnaires were presented to housewives living in the area of Kyung-ju city, who responded the questionnaires under direct interview. The questionnaire was composed of two parts. One part included demographic data, somatic complaints, drug use, places of drug purchase, current diseases that had been diagnosed by doctors. The other included Korean standard Beck Depression Inventory-questionnaire. The subjects were divided into two groups by BDI score(21 point), which was the cut-off point for depression in Korea. The relationships of somatic symptoms and drug use between the two groups were analyzed. RESULTS: There were 110 housewives who had depressive trends among 569 respondents. In general characteristics, there was significant difference between the two groups except the item of religion. In the items of somatic symptoms, there were more somatic symptoms in the group of high BDI score(>_21) except fatigue(P<0.01). More drug users were found in the group of high BDI score(>_21) (P<0.05). In the group of high BDI score(>_21), there was definite correlation between the items of somatic symptoms and drug use. There was no difference between the two groups in the item of drug purchase site. The most common site of drug purchase was the drug store in both groups. CONCLUSIONS: Depressive housewives complained of more somatic symptoms and more often used drugs as well.
Surveys and Questionnaires ; Depression ; Drug Users ; Female ; Gyeongsangbuk-do ; Humans ; Korea ; Male ; Prevalence