Objective To study the effect of Shuxuening injection on treatment of left ventricular diastolic dysfunction.Methods Ninety cases of left ventricular diastolic dysfunction were divided into control group and test group randomly,45 cases for each group.Both groups were treated with standard management and the treatment group was given Shuxuening injection(20 mL) additionally for 2 weeks.E/A ratio,peak E,peak A,LVEF were observed before and after treatment.Result The clinical symptoms of the two groups were all improved after treatment.The test group had a higher overall effective rate than the control group.The ventricular diastolic function paramenters(E/A ratio,peak E,peak A,LVEF) in the test group were much better than that in the control group.Conclusion Shuxuening injection can improve the clinical symptoms and signs of left ventricular diastolic dysfunction.