1.Application of nursing inspection log on nursing quality control
Mei CHEN ; Nairong MA ; Yu MA ; Xiaojuan JI
Chinese Journal of Modern Nursing 2014;20(13):1577-1579
Objective To study the role of nursing inspection log in the management of nursing quality control.Methods Totals of 10 wards of internal medicine were randomized into the intervention group (5 wards) and the control group (5 wards).From January 2012,nursing inspections log was used in the intervention group,combined with the rounds of the wards to inspect the daily work.The existed problem of last week was reviewed every week.Specified nurse was responsible for the quality control and recorded when the head nurse was off the shift.The head nurse checked the results of quality control regularly.The incidence of adverse events and quality control results were compared between groups.Results In the intervention group,the times of adverse events of completion of core system,nursing quality of hospital admission and discharge,nursing quality of severe patients,quality of nursing document,quality of disinfection and isolation and quality of wards' management were 26,28,25,15,10 and 14,which were less than 52,48,40,30,23 and 28 in the control group.The differences were significant (x2 =11.93,7.45,4.87,6.32,6.17,5.86,respectively; P < 0.05).The control group discharged 6 259 patients,and the intervention group discharged 6 347 patients.The total number of adverse events was 32 patients in the intervention group (0.50%) and 73 patients in the control group (1.17%).The difference was significant (x2 =16.73,P < 0.05).Conclusions The inspection log can improve nursing quality control and decrease adverse events.
2.Associations of genetic polymorphisms in Corin with blood pressure responses to salt and potassium intake
Lan WANG ; Zejiaxin NIU ; Yanjie GUO ; Nairong LIU ; Yanni YAO ; Beibei YANG ; Jiaxin WANG ; Chuang LI ; Panpan LIU ; Chang’e YANG ; Mingfei DU ; Guilin HU ; Xi ZHANG ; Dan WANG ; Xiaoyu ZHANG ; Chao CHU ; Yueyuan LIAO ; Qiong MA ; Keke WANG ; Hao JIA ; Yue SUN ; Tongshuai GUO ; Weihua GAO ; Jianjun MU ; Yang WANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2023;44(1):22-29
【Objective】 Corin, a transmembrane serine protease that can cleave atrial natriuretic peptide precursor (pro-ANP) into atrial natriuretic peptide with smaller bioactive molecules, participates in the pathophysiological process of hypertension and cardiac hypertrophy. The purpose of this study was to explore the relationship of Corin gene variation with blood pressure responses to sodium and potassium dietary interventions. 【Methods】 In 2004, we recruited 514 participants from 124 families in 7 villages of Baoji, Shaanxi Province, China. All the subjects received a 3-day normal diet, a 7-day low-salt diet, a 7-day high-salt diet, and finally a 7-day high-salt and potassium supplementation. Fifteen single nucleotide polymorphisms (SNPs) of Corin gene were selected for final analysis. 【Results】 SNPs rs12509275 were significantly associated with diastolic blood pressure (DBP) response to low-salt diet, while rs3749584 was associated with pulse pressure (PP) response to low-salt diet.SNP rs3749584 and rs10517195 were significantly associated with PP response to high-salt diet. In addition,rs17654278 were significantly associated with systolic blood pressure (SBP) response to high-salt and potassium supplementation, rs2271037 was significantly correlated with DBP responses to high-salt and potassium supplementation, and rs4695253, rs12509275, rs2351783, rs36090894 were significantly associated with PP response to high-salt and potassium supplementation. 【Conclusion】 Corin gene polymorphisms were associated with blood pressure response to sodium and potassium, suggesting that Corin gene may be involved in pathophysiological process of salt sensitivity and potassium sensitivity.