1.Diagnostic Method, Eradication Therapy and Prevention of Helicobacter pylori Infection.
Journal of the Korean Medical Association 1997;40(9):1187-1194
No abstract available.
Helicobacter pylori*
;
Helicobacter*
2.What Happened to Him Using the Freight Elevator: Fall from Height or Caught Between?.
Hyoung Joong KIM ; Joo Young NA
Korean Journal of Legal Medicine 2013;37(3):153-156
There has been an increase in the incidence of elevator-related accidents in the Republic of Korea. Every year, approximately 10~20 elevator-related fatalities are reported in the Republic of Korea. According to research from the United States, 'falls' were the most common cause of death, followed by 'caught in/between'. In such investigations, it is important to distinguish between the manners of death. Herein, we report an elevator-related fatality, which required careful forensic investigation to determine the cause of death. A thorough forensic autopsy and reinvestigation of the death scene by medical examiners were required to determine if the death was caused as a result of the deceased falling from from a height or being caught in between the elevator and the wall of building.
Autopsy
;
Cause of Death
;
Coroners and Medical Examiners
;
Elevators and Escalators
;
Humans
;
Incidence
;
Republic of Korea
;
United States
4.The Prevalence of Epstein-Barr Virus in Uterine Cervical Cancer: Detection by PCR and In Situ PCR Methods.
In Sun KIM ; Jae Seong KANG ; An Na CHOI ; Young Sik KIM
Korean Journal of Obstetrics and Gynecology 2000;43(2):184-191
OBJECTIVE: Uterine cervical cancer is the most common malignant tumor in Korean women. Human papillomaviruses are associated in 85-90% of the cases. However, other cofactors are considered to be important in carcinogenesis. There is an evidence that the uterine cervix is the site of shedding of the Epstein-Barr viruses(EBV). Furthermore the virus has been detected in cervical intraepithelial neoplasia and invasive carcinoma of the uterine cervix. We studied to evaluate the role of EBV in cervical carcinogenesis. METHODS: Non-neoplastic cervices(12), carcinoma in situ(32), microinvasive squamous cell carcinomas(9), invasive squamous cell carcinomas(37) and adenocarcinomas and adenosquamous carcinomas(14) were studied for EBV infection. PCR and in situ PCR for EBNA-1 were done and subtyping was done using PCR for EBNA 3C. RESULTS: In non-neoplastic cervix, EBV was detected in 16.7% by PCR and found in normal epithelial cells and lymphocytes in in situ PCR. By PCR technique, EBV was detected in 65.6% of CIS, 66.3% and 51.4% of microinvasive and invasive squamous cell carcinomas, 57.1% of adenocarcinomas and adenosquamous carcinomas. EBV subtyping was done in EBV positive cases by PCR and all showed type 1. CONCLUSION: EBV was detected in higher frequency in cervical cancer than in non-neoplastic cervix. However the frequency was not correlated to the invasion depth and histologic types of cervical carcinomas. EBV was detected in tumor cells as well as normal epithelial cells and lymphocytes also. It was suggested that EBV may play a role in cervical cancers but the mechanism in carcinogenesis remains to be solved.
Adenocarcinoma
;
Carcinogenesis
;
Carcinoma, Adenosquamous
;
Carcinoma, Squamous Cell
;
Cervical Intraepithelial Neoplasia
;
Cervix Uteri
;
Epithelial Cells
;
Epstein-Barr Virus Infections
;
Female
;
Herpesvirus 4, Human*
;
Humans
;
Lymphocytes
;
Polymerase Chain Reaction*
;
Prevalence*
;
Uterine Cervical Neoplasms*
5.Implementing a Sepsis Resuscitation Bundle Improved Clinical Outcome: A Before-and-After Study.
Jeongmin KIM ; Sungwon NA ; Young Chul YOO ; Shin Ok KOH
Korean Journal of Critical Care Medicine 2014;29(4):250-256
BACKGROUND: Unlike other diseases, the management of sepsis has not been fully integrated in our daily practice. The aim of this study was to determine whether repeated training could improve compliance with a 6-h resuscitation bundle in patients with severe sepsis and septic shock. METHODS: Repeated education regarding a sepsis bundle was provided to the intensive care unit and emergency department residents, nurses, and faculties in a single university hospital. The educational program was led by a multidisciplinary team. A total of 175 adult patients with severe sepsis or septic shock were identified (88 before and 87 after the educational program). Hemodynamic resuscitation bundle and timely antibiotics administration were measured for all cases and mortality at 28 days after sepsis diagnosis was evaluated. RESULTS: The compliance rate for the sepsis resuscitation bundle before the educational program was poor (0%), and repeated training improved it to 80% (p < 0.001). The 28-day mortality was significantly lower in the intervention group (16% vs. 32%, p = 0.040). Within the intervention group, patients for whom the resuscitation bundle was successfully completed had a significantly lower 28-day mortality than other patients (11% vs. 41%, p = 0.004). CONCLUSIONS: Repeated education led by a multidisciplinary team and interdisciplinary communication improved the compliance rate of the 6-h resuscitation bundle in severe sepsis and septic shock patients. Compliance with the sepsis resuscitation bundle was associated with improved 28-day mortality in the study population.
Adult
;
Anti-Bacterial Agents
;
Compliance
;
Critical Pathways
;
Diagnosis
;
Education
;
Emergency Service, Hospital
;
Hemodynamics
;
Humans
;
Intensive Care Units
;
Interdisciplinary Communication
;
Mortality
;
Resuscitation*
;
Sepsis*
;
Shock, Septic
6.A Case of Adult Onset Still's Disease.
Na Young YOON ; Bo Kyung KIM ; Sung Ku AHN
Korean Journal of Dermatology 2013;51(6):486-487
No abstract available.
Adult
;
Humans
;
Still's Disease, Adult-Onset
7.Blood Conservation Strategy during Cardiac Valve Surgery in Jehovah's Witnesses: a Comparative Study with Non-Jehovah's Witnesses.
Tae Sik KIM ; Jong Hyun LEE ; Chan Young NA
Korean Journal of Critical Care Medicine 2016;31(2):101-110
BACKGROUND: We compared the clinical outcomes of cardiac valve surgery in adult Jehovah's Witness patients refusing blood transfusion to those in non-Jehovah's Witness patients without any transfusion limitations. METHODS: From 2005 to 2014, 25 Jehovah's Witnesses (JW group) underwent cardiac valve surgery using a blood conservation strategy. Twenty-five matched control patients (non-JW group) were selected according to sex, age, operation date, and surgeon. Both groups were managed according to general guidelines of anticoagulation for valve surgery. RESULTS: The operative mortality rate was 4.0% in the JW group and 0% in the non-JW group (p = 1.000). There was no difference in postoperative major complications between the groups (p = 1.000). The overall survival rate at 5 and 10 years was 85.6% ± 7.9% and 85.6% ± 7.9% in the JW group, respectively, and 100.0% ± 0.0% and 66.7% ± 27.2% in the non-JW group (p = 0.313). The valve-related morbidity-free survival rates (p = 0.625) and late morbidity-free survival rates (p = 0.885) were not significantly different between the groups. CONCLUSIONS: Using a perioperative strategy for blood conservation, cardiac valve surgery without transfusion had comparable clinical outcomes in adult patients. This blood conservation strategy could be broadly applied to major surgeries with careful perioperative care.
Adult
;
Blood Transfusion
;
Bloodless Medical and Surgical Procedures*
;
Heart Valves*
;
Humans
;
Jehovah's Witnesses*
;
Mortality
;
Perioperative Care
;
Survival Rate
8.Defense style of neurotic patients: focused on the Christian.
Na Young HWANG ; Man Hong LEE ; Yim KIM
Journal of Korean Neuropsychiatric Association 1992;31(1):157-170
No abstract available.
Humans
9.Clinical Review of Ten Years' Pediatric Surgical Diseases.
Soo Jin Na CHOI ; Sang Young CHUNG ; Shin Kon KIM
Journal of the Korean Association of Pediatric Surgeons 1998;4(2):110-116
A clinical review was made on 2,191 cases of general pediatric surgery under the age of 15 years which were operated upon at the Divisionof Pediatric Surgery, Department of Surgery, Chonnam University Hospital from January 1988 to December 1997. The number of operations in pediatric age were 13,144 (13.2%) out of total 99,555 operations at Chonnam University Hospital and the most prevalent age group was under 1 year of age (14.3%). The number of operations in Divisionof General Pediatric Surgery were 2,191 (16.7%) out of total 13,144 operations in pediatric age and the incidence of patients under 1 year of age in general pediatric surgery was 42.9% (941/2,191). The prevalent diseases under 1 month of age were anorectal malformations (20.6%) and hypertrophic pyloric stenosis (20.3%) and between 1 month to 1 year of age were inguinal hernia (32.4%) and intussusception (19.6%). The total motality rate in neonatal intensive care unit was 31.3%. Gastroschisis presented highest mortality.
Gastroschisis
;
Hernia, Inguinal
;
Humans
;
Incidence
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Intussusception
;
Jeollanam-do
;
Mortality
;
Pyloric Stenosis, Hypertrophic
10.A Clinicopathological Study of Posttransplant Liver Biopsy.
Na Rae KIM ; Dae Su KIM ; Young Lyun OH ; Mi Kyung KIM ; Young Hyeh KO
Korean Journal of Pathology 1999;33(3):169-178
Liver biopsies are used routinely in the assessment of graft dysfunction following liver transplantation and generally considered to be the most reliable method for the diagnosis of posttransplant complications with overlapping clinical and laboratory findings. To investigate posttransplant complications causing graft dysfunction and usefulness of liver biopsy, we analysed clinicopathologic features of 65 posttransplant liver biopsies, 2 autopsies and an explanted liver, taken from 20 patients. The frequencies of posttransplant complications were acute cellular rejection in 9 patients (45%), postoperative infection in 11 patients (55%), of which cytomegalovirus (CMV) infection and systemic invasive aspergillosis with candidiasis occured in 10 patients (50%) and 1 patient (5%), respectively. Remainders were hepatic arterial thrombosis in two (10%), primary graft dysfunction due to fatty donor liver in one (5%), and posttransplant lymphoproliferative disorder (PTLD) in two (10%). There were no chronic rejection or recurrent disease. Postoperative mortality was 25%. Histologic grade by Banff schema was well correlated with clinical parameters associated with unfavorable short term prognosis. CMV infection was associated with acute cellular rejection in 6 out of 10 patients (60%). Immunohistochemical staining for CMV was more sensitive method than CMV in situ hybridization or histologic detection of viral inclusion on tissue section. It was unique that one case of PTLD developed under the circumstances of the lowest dosage of immunosuppression and took grave outcome. Based on these results, we concluded that clinicopathologic correlation with integration of all the clinical and laboratory findings is necessary in the interpretation of accurate and early diagnosis of posttransplant liver biopsies. The interrelationship between chronic rejection and CMV infection as well as pathogenetic factors of PTLD remains to be clarified through further ongoing observation.
Aspergillosis
;
Autopsy
;
Biopsy*
;
Candidiasis
;
Cytomegalovirus
;
Diagnosis
;
Early Diagnosis
;
Humans
;
Immunosuppression
;
In Situ Hybridization
;
Liver Transplantation
;
Liver*
;
Lymphoproliferative Disorders
;
Mortality
;
Primary Graft Dysfunction
;
Prognosis
;
Thrombosis
;
Tissue Donors
;
Transplants