PURPOSE: The purpose of this study is to describe the anglographic findings of collateral vessels in cervicofacial vascular lesions with previously ligated carotid arteries and to evaluate the extent of anglographic assessmant needed before embolization. MATERIALS AND METHODS: We retrospectively reviewed 10 cervicofacial vascular lesions with previously ligated carotid artery, which were 6 cases of arteriovenous malformation, 2 cases of carotid cavernous fistula, 1 case of hemangioma and 1 case of arteriovenous realformation with carotid cavernous fistula. The previously ligated arteries are proximal external carotid artery (n=5), branches of external carotid artery (n=2) and common carotid artery (n=3). Common carotid artery or internal carotid artery (n=9), vertebral artery (n=5), ipsilateral external carotid artery (n=4), contralateral external carotid artery (n=5), costocervical trunk (n=2), thyrocervical trunk (n=2) were assessed by conventional angiography. Angiography of both carotid and vertebral arteries was performed in 5 cases. RESULTS: The collateral vascular channels were inferolateral trunk of internal carotid artery (n=8), vertebral artery (n=5), contralateral external carotid artery (n=5), ipsilateral external carotid artery (n=4), deep cervical artery (n=2) and ascending cervical artery (n=l). Embolizations were performed in 9 cases with operative cannulation(n=4), embolization via collateral branches of ipsilateral external carotid artery (n=l), embolization via collateral branches of contralateral external carotid artery (n=3) and balloon occulusion via direct puncture (n=l). CONCLUSION: The collateral channels in cervicofacial vascular lesions with previouly ligated carotid artery were inferolateral trunk of internal carotid artery, contralateral or ipsilateral external carotid artery, vertebral artery, deep cervical artery and ascending cervical artery on angiography. Complete anglographic assessment of possible collateral channels is mandatory for the effective and safe embolization.
Angiography ; Arteries ; Arteriovenous Malformations ; Carotid Arteries* ; Carotid Artery, Common ; Carotid Artery, External ; Carotid Artery, Internal ; Fistula ; Hemangioma ; Punctures ; Retrospective Studies ; Vertebral Artery

Objectives: This study compares and analyzes the effects of objective body mass index (BMI) and subjective body image on self-perceived oral health among Korean adults based on sex differences. Methods: Raw data were obtained from the 7th (2016-2018), 8th (2019), and 9th (2022) Korea National Health and Nutrition Examination Surveys. The study included 24,817 adults, with objective body type and subjective body image as the independent variables and self-perceived oral health status as the dependent variable. The results were analyzed by sex using complex sample logistic regression analysis with IBM SPSS Statistics. Results: An analysis of the impact of objective body type on poor self-perceived oral health status showed no significant difference for males, whereas the odds ratio was significant for females, with objective obesity at 1.167 (P<0.001). An analysis of the effect of subjective body image on poor self-perceived oral health status revealed that the odds ratio was significant for males with subjective obesity (OR 1.482, P<0.001). For females, the odds ratio was 1.225 for subjective overweight and 1.379 for subjective obesity, indicating that females were significantly more likely to perceive their oral health as poor (P<0.001). Conclusions Both males and females were more influenced by subjective body image than objective body type, and females were more sensitive than males to the impact of body type on their self-perceived oral health status. Although males were generally less sensitive about their body type, they were more likely than females to perceive their oral health negatively.

Objectives: This study compares and analyzes the effects of objective body mass index (BMI) and subjective body image on self-perceived oral health among Korean adults based on sex differences. Methods: Raw data were obtained from the 7th (2016-2018), 8th (2019), and 9th (2022) Korea National Health and Nutrition Examination Surveys. The study included 24,817 adults, with objective body type and subjective body image as the independent variables and self-perceived oral health status as the dependent variable. The results were analyzed by sex using complex sample logistic regression analysis with IBM SPSS Statistics. Results: An analysis of the impact of objective body type on poor self-perceived oral health status showed no significant difference for males, whereas the odds ratio was significant for females, with objective obesity at 1.167 (P<0.001). An analysis of the effect of subjective body image on poor self-perceived oral health status revealed that the odds ratio was significant for males with subjective obesity (OR 1.482, P<0.001). For females, the odds ratio was 1.225 for subjective overweight and 1.379 for subjective obesity, indicating that females were significantly more likely to perceive their oral health as poor (P<0.001). Conclusions Both males and females were more influenced by subjective body image than objective body type, and females were more sensitive than males to the impact of body type on their self-perceived oral health status. Although males were generally less sensitive about their body type, they were more likely than females to perceive their oral health negatively.

Objectives: This study compares and analyzes the effects of objective body mass index (BMI) and subjective body image on self-perceived oral health among Korean adults based on sex differences. Methods: Raw data were obtained from the 7th (2016-2018), 8th (2019), and 9th (2022) Korea National Health and Nutrition Examination Surveys. The study included 24,817 adults, with objective body type and subjective body image as the independent variables and self-perceived oral health status as the dependent variable. The results were analyzed by sex using complex sample logistic regression analysis with IBM SPSS Statistics. Results: An analysis of the impact of objective body type on poor self-perceived oral health status showed no significant difference for males, whereas the odds ratio was significant for females, with objective obesity at 1.167 (P<0.001). An analysis of the effect of subjective body image on poor self-perceived oral health status revealed that the odds ratio was significant for males with subjective obesity (OR 1.482, P<0.001). For females, the odds ratio was 1.225 for subjective overweight and 1.379 for subjective obesity, indicating that females were significantly more likely to perceive their oral health as poor (P<0.001). Conclusions Both males and females were more influenced by subjective body image than objective body type, and females were more sensitive than males to the impact of body type on their self-perceived oral health status. Although males were generally less sensitive about their body type, they were more likely than females to perceive their oral health negatively.

Objectives: This study compares and analyzes the effects of objective body mass index (BMI) and subjective body image on self-perceived oral health among Korean adults based on sex differences. Methods: Raw data were obtained from the 7th (2016-2018), 8th (2019), and 9th (2022) Korea National Health and Nutrition Examination Surveys. The study included 24,817 adults, with objective body type and subjective body image as the independent variables and self-perceived oral health status as the dependent variable. The results were analyzed by sex using complex sample logistic regression analysis with IBM SPSS Statistics. Results: An analysis of the impact of objective body type on poor self-perceived oral health status showed no significant difference for males, whereas the odds ratio was significant for females, with objective obesity at 1.167 (P<0.001). An analysis of the effect of subjective body image on poor self-perceived oral health status revealed that the odds ratio was significant for males with subjective obesity (OR 1.482, P<0.001). For females, the odds ratio was 1.225 for subjective overweight and 1.379 for subjective obesity, indicating that females were significantly more likely to perceive their oral health as poor (P<0.001). Conclusions Both males and females were more influenced by subjective body image than objective body type, and females were more sensitive than males to the impact of body type on their self-perceived oral health status. Although males were generally less sensitive about their body type, they were more likely than females to perceive their oral health negatively.

We herein report a case of intractable epilepsy that occurred in a 7-year-old girl, which is consistent with radiological and clinicopathological hallmarks of Rasmussen's encephalitis. The patient showed characteristic primary unilateral involvement with secondary bilateral propagation. Microscopically, the cortical atrophy due to neuronal loss, intense GFAP-immunoreactive astrogliosis, neuronophagia, perivascular lymphocytic infiltration and microglial nodules was seen throughout the cortex and white matter. No viral inclusions were noted; no cytomegalovirus, herpes simplex virus or Epstein-Barr virus was found by in situ hybridization. Granular immunofluorescence for C4, C1q and IgG within the blood vessel walls was noted, and ultrastructurally, only nonspecific vascular injury was found. Rasmussen's encephalitis is a diagnosis of exclusion; it can be diagnosed by the combination of clinical manifestation, neuroimaging and characteristic pathologic features.
Atrophy ; Blood Vessels ; Child ; Cytomegalovirus ; Diagnosis ; Encephalitis* ; Epilepsy ; Female ; Fluorescent Antibody Technique ; Herpesvirus 4, Human ; Humans ; Immunoglobulin G ; Immunohistochemistry ; In Situ Hybridization ; Microscopy, Electron ; Neuroimaging ; Neurons ; Simplexvirus ; Vascular System Injuries

BACKGROUND: Pulmonary vessel sarcomas are rare, and their pathogenesis is still unclear. METHODS: We focus on the pathologic findings of fourteen pulmonary artery and/or vein sarcomas along with clinical prognosis. RESULTS: Nine patients were male and five were female, and they ranged in age from 26 to 72 years (mean, 47 years). There were ten cases of pulmonary artery sarcoma, three cases of pulmonary artery and vein sarcoma, and one case of pure pulmonary vein sarcoma. Ten out of the fourteen cases were associated with pulmonary thromboembolism. Microscopically, all the tumors showed an undifferentiated sarcomatous portion. There were leiomyosarcoma portions in 8 cases, malignant fibrous histiocytomatous portions in 7 cases, angiosarcomatous differentiation in 3 cases, and osteosarcomatous portion in 1 case. All but two patients died during the follow up period (range, 1 to 78 months). The mean survival time of the patients who died was 14 months and the longest survival time was 78 months after surgical resection. CONCLUSIONS: The current study is one of the largest single institutional reviews of pulmonary artery and/or vein sarcoma. Regardless of the histological components and macroscopic growth patterns, these rare tumors have a grave prognosis.
Female ; Follow-Up Studies ; Glycosaminoglycans ; Humans ; Leiomyosarcoma ; Male ; Prognosis ; Pulmonary Artery ; Pulmonary Embolism ; Pulmonary Veins ; Sarcoma ; Survival Rate ; Veins

No abstract available.
Humans ; Needles* ; Peritonsillar Abscess*

Background: A decrease in computed tomography (CT)-derived skeletal muscle radiodensity (SMD) reflects age-related ectopic fat infiltration of muscle, compromising muscle function and metabolism. We investigated the age-related trajectory of SMD and its association with vertebral trabecular bone density in healthy adults. Methods: In a cohort of healthy adult kidney donors aged 19 to 69 years (n=583), skeletal muscle index (SMI, skeletal muscle area/height2), SMD, and visceral-to-subcutaneous fat (V/S) ratio were analyzed at the level of L3 from preoperative CT scans. Low bone mass was defined as an L1 trabecular Hounsfield unit (HU) <160 HU. Results: L3SMD showed constant decline from the second decade (annual change –0.38% and –0.43% in men and women), whereas the decline of L3SMI became evident only after the fourth decade of life (–0.37% and –0.18% in men and women). One HU decline in L3SMD was associated with elevated odds of low bone mass (adjusted odds ratio, 1.07; 95% confidence interval, 1.02 to 1.13; P=0.003), independent of L3SMI, age, sex, and V/S ratio, with better discriminatory ability compared to L3SMI (area under the receiver-operating characteristics curve 0.68 vs. 0.53, P<0.001). L3SMD improved the identification of low bone mass when added to age, sex, V/S ratio, and L3SMI (category-free net reclassification improvement 0.349, P<0.001; integrated discrimination improvement 0.015, P=0.0165). Conclusion L3SMD can be an early marker for age-related musculoskeletal changes showing linear decline throughout life from the second decade in healthy adults, with potential diagnostic value for individuals with low bone mass.

Recent research suggests that a small group of cells, named cancer stem cells (CSCs), is responsible for initiating tumor formation, recurrence, and metastasis. c-Yes, a proto-oncogene that is a subfamily of Src family kinase, is often activated in human colon cancer; this implicates c-Yes in the onset and progression of the disease. The objective of this study was to investigate the correlation between c-Yes and CSCs. We performed a sphere formation assay and reverse transcription-polymerase chain reaction for studying the differentiation of HT-29 human colon CSCs. To demonstrate the specific role of c-Yes in CSCs, we performed live cell microscopy and a cell cycle assay. These study shows, for the first time, that c-Yes is enriched in CD133+ CSCs, compared to their CD133− counterparts, and that c-Yes depletion in CD133+ cells induces cell differentiation. Moreover, c-Yes depletion was found to elongate the midbody and increase the proliferation doubling time. This also suggested that the misregulation of microtubules during chromosomal separation causes aneuploidy. Our results suggest that c-Yes may play a crucial role in initiating, maintaining, and driving the tumorigenic property of colon cancer.
Aneuploidy ; Cell Cycle ; Cell Differentiation ; Colon* ; Colonic Neoplasms* ; Humans* ; Microscopy ; Microtubules ; Neoplasm Metastasis ; Neoplastic Stem Cells ; Phosphotransferases ; Proto-Oncogenes ; Recurrence ; Stem Cells*