Cutaneous horn is a clinical description for a cohesive mass of cornified material protruding from the surface of the skin. These lesions may arise from a bulging erythematous base, and their shape is usually described as conical. Such lesions generally occur on sun exposed areas such as the face, ear or the dorsum of the hand. Cutaneous horn is not a pathological diagnosis and a variety of primary underlying processes can cause this lesion. We report an 85-year-old female who presented with a bean-sized, hyperkeratotic nodule on the right lower leg. Clinical and histopathologic examination confirmed the nodule to be squamous cell carcinoma presenting as cutaneous horn.
Aged, 80 and over ; Animals ; Carcinoma, Squamous Cell* ; Diagnosis ; Ear ; Female ; Hand ; Horns* ; Humans ; Leg ; Skin ; Solar System

Liposarcoma is a rare mesenchymal tumor that occurs most commonly in the soft tissue of the extremities. It develops deeply in the intramuscular fatty tissue and consists of lipoblasts. We experienced a case of well-differentiated liposarcoma on the thigh of a 48-year-old female, who presented with a skin-colored, child fist-sized mass. Liposarcoma is rare in the dermatologic field, so we herein report a case of well-differentiated liposarcoma.
Adipose Tissue ; Child ; Extremities ; Female ; Humans ; Liposarcoma* ; Middle Aged ; Thigh

Clear cell sarcoma is a rare malignant tumor representing about 1% of soft tissue tumors. It usually presents in the distal extremities of young adults, frequently attached to tendons or aponeuroses. This slowly progressive tumor tends to recur and results in eventual development of metastatic growth. Early recognition of the disease and prompt wide excision of tumor are essential to get a favorable outcome. We report a rare case of clear cell sarcoma in a 57 year-old female who presented with an erythematous hard nodule on her abdomen.
Abdomen ; Extremities ; Female ; Humans ; Sarcoma, Clear Cell ; Tendons ; Young Adult

Dermatofibromas normally occur on the extremities of young adults as an indolent, single nodule. They are usually smaller than 1 cm, but can occasionally measure up to 2 to 3 cm in size. Depending on the proportion of fibrous tissue, lipids, and hemosiderin, the nodule color is variable. There are some variants of dermatofibroma; fibrous type, cellular type, aneurysmal type and atypical type. Moreover, a new variant of dermataofibroma was reported in 1986 for the first time. Histologically, this new variant showed nuclear palisading in the central portion of the tumor. We report a 17-year-old male who presented with a pea-sized, brownish, subcutaneous hard nodule on his back, which upon clinical and histopathologic examination showed palisading dermatofibroma.
Adolescent ; Aneurysm ; Extremities ; Hemosiderin ; Histiocytoma, Benign Fibrous* ; Humans ; Male ; Young Adult

A nevus with cyst is defined as a single lesion of a melanocytic nevus, and this is commonly associated with an epidermal cyst. For the previously reported cases of a nevus with cyst, most of the melanocytic nevi were of the intradermal or compound type. There have been rare reported cases of dysplastic nevus, blue nevus, Spitz nevus, congenital melanocytic nevus and so forth. We report here on a rare case of congenital melanocytic nevus combined with an epidermal cyst in a 21-year-old woman.
Dysplastic Nevus Syndrome ; Epidermal Cyst ; Female ; Humans ; Nevus ; Nevus, Blue ; Nevus, Epithelioid and Spindle Cell ; Nevus, Pigmented ; Young Adult

Epidermal nevus arises from the pluripotential germinative cells in the basal layer of the embryonic epidermis. Histologically, it has a distinctive feature of hyperkeratosis, papillomatosis and acanthosis with elongation of the rete ridges. Epidermal nevus also has other histological variations. We report a case of a 5-year-old male who presented with pruritic linear brownish scaly papules on the right thigh. The lesion showed histological features of combined epidermolytic hyperkeratosis and porokeratosis type of epidermal nevus.
Child, Preschool ; Epidermis ; Humans ; Hyperkeratosis, Epidermolytic* ; Male ; Nevus* ; Papilloma ; Porokeratosis* ; Thigh

Cutaneous, diffuse, large B-cell lymphoma (DLBCL) is characterized by a diffuse dermal infiltration which is composed of large centroblasts and immunoblasts. It is subdivided into a primary form arising from the skin and a secondary form which is metastasized from the lymph node. Secondary DLBCL has a more aggressive clinical course than the primary form. We report a 39-year-old female patient who presented with a 2 cm sized, erythematous, subcutaneous nodule on her left upper arm. She had been treated for brain-diffuse, large B-cell lymphoma which occurred 5 years before. The histopathologic and immunohistochemical examinations of the skin lesion also showed diffuse, large, B-cell lymphoma.
Adult ; Arm ; B-Lymphocytes* ; Female ; Humans ; Lymph Nodes ; Lymphoma, B-Cell* ; Skin

Benign cephalic histiocytosis (BCH) is a rare non-Langerhans cell histiocytosis of unknown etiology. Clinically, lesions are characterized by small, red-to-yellow papules distributed mainly on the head, face, neck, and shoulders of infants and children. Histopathological specimens show massive histiocytic infiltration of the superficial dermis. Immunohistochemically, they are positive for CD68, but negative for CD1a and S-100. Two cases have been reported so far in the relevant work published in Korean literature. Herein, we report on an additional case of BCH.
Child ; Dermis ; Head ; Histiocytosis ; Humans ; Infant ; Neck ; Shoulder

BACKGROUND: Quality of life (QOL) is a broad concept that encompasses all aspects of an individual's existence. Acne is a common inflammatory dermatosis which most frequently affects the face, and produces significant psychological and physical scarring. OBJECTIVE: The aim of this study was to compare QOL in patients with acne and healthy controls by using the WHO QOL Scale, and to assess QOL of patients with acne by using the generic (WHO Quality of life scale), dermatology-specific (Skindex-29) and acne-specific (APSEA) questionnaires. The relationship between clinical characteristics and QOL were explored. Additionally, financial values which patients attach to the treatment for their acne were determined. METHODS: 170 acne patients and 41 healthy controls were recruited in this study and completed the WHO QOL- BREF Scale. Total scores and scores of domains of the WHO QOL Scale in the two groups were compared. Correlation analysis and multiple regression analysis were performed to examine the relationship between the quality of life and the clinical characteristics of patients with acne. RESULTS: Total score of WHO QOL scale in patients with acne were decreased compared to those in healthy controls. Clinical characteristics, including the severity of depression and anxiety, disease duration, clinical severity and self-reported severity (SRS), showed significant correlation with QOL. Multiple regression analysis revealed that the severity of depression and anxiety, and SRS were factors directly affecting the QOL in the patients with acne. As for financial aspects, 27.6% of patients would pay 100,000~500,000 won for acne treatment, but 33.5% of patients answered they would not pay when cost of treatment exceeded 100,000 won. CONCLUSION: QOL in patients with acne was poorer than that of healthy controls. The association between QOL and SRS was stronger than QOL and clinical severity. The severity of depression and anxiety was the most important predictor on QOL.
Acne Vulgaris* ; Anxiety ; Cicatrix ; Depression ; Humans ; Quality of Life* ; Skin Diseases

Impetigo herpetiformis is a rare, severe dermatologic disorder that is similar to a type of pustular psoriasis that predominantly occurs during the 3rd trimester of pregnancy. This condition usually resolves after delivery and it rarely continues until the postpartum period. Systemic corticosteroids have proven to be the drug of choice for the management of impetigo herpetiformis. In the postpartum period, oral retinoids such as isotretinoin, etretinate and acitretin can be used to control impetigo herpetiformis, but their side effect such as teratogenicity is a big issue to women of child-bearing age. We report here on a case of impetigo herpetiformis in a 28-year-old woman who did not respond to oral corticosteroids, but she was treated successfully with cyclosporine. To the best of our knowledge this is the first case of impetigo herpetiformis treated with cyclosporine in the Korean medical literature.
Acitretin ; Adrenal Cortex Hormones ; Adult ; Cyclosporine ; Etretinate ; Female ; Humans ; Impetigo ; Isotretinoin ; Postpartum Period ; Pregnancy ; Psoriasis ; Retinoids