1.A Case of Chronic Neutrophilic Leukemia Associated with Increased Respiratory Burst Activity of Neutrophils.
Na RanHi LEE ; Seock Ah IM ; Kyung Eun LEE ; Do Yeun KIM ; Eun Mi NAM ; Seong Eun KIM ; So Hyeon LEE ; Ji Eun CHANG ; Jee Eun CHANG ; Moon Sun YEOUM ; Hae Jung YEOUM ; Jung Mi KWON ; Young Ju CHOI ; Chu Myoung SEONG ; Soon Nam LEE ; Ju Young SEO ; Hee Jin HUH ; Wha Soon CHUNG
Korean Journal of Hematology 2001;36(4):359-363
Chronic neutrophilic leukemia is a rare myeloproliferative disorder. We have experienced a typical case of chronic neutrophilic leukemia in a 76-year-old man who complained abdominal distension due to hepatosplenomegaly. White blood cell count of peripheral blood was 50,500/nL with 90% segmented neutrophils. The underlying disease for a leukemoid reaction had not been detected. Leukocyte alkaline phosphatase score and the serum levels of vitamin B12 and uric acid were elevated. Chromosome study showed a normal karyotype without Philadelphia chromosome or bcr/abl rearrangement. Phorbol myristate acetate-activated respiratory burst activity of neutrophils measured with chemiluminescence showed increased activity.
Aged
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Alkaline Phosphatase
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Humans
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Karyotype
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Leukemia, Neutrophilic, Chronic*
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Leukemoid Reaction
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Leukocyte Count
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Leukocytes
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Luminescence
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Myeloproliferative Disorders
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Myristic Acid
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Neutrophils*
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Philadelphia Chromosome
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Respiratory Burst*
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Uric Acid
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Vitamin B 12
Result Analysis
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