1.Identification and cDNA Cloning of the Leptin Receptor Long from ( OB-Rb ) from Rat Splenocytes.
Jung Hyun PARK ; Sung Kyu JU ; Shin Young NA ; Kwan Hee YOU ; Kil Lyong KIM
Korean Journal of Immunology 2000;22(1):31-38
No abstract available.
Animals
;
Clone Cells*
;
Cloning, Organism*
;
DNA, Complementary*
;
Leptin*
;
Rats*
;
Receptors, Leptin*
2.Study on the treatment of childhood acute lymphoblastic leukemia.
Sang Oh NA ; Hee Young SHIN ; Hyo Seop AHN ; Sang Kyu PARK
Journal of the Korean Cancer Association 1992;24(3):390-400
No abstract available.
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
3.A statistical study of dermatoses in soldiers from 1987-1989.
Jin Ho CHUNG ; Jong Hee NA ; Moon Soo YOON ; Young Il CHUN ; Yoo Shin LEE
Korean Journal of Dermatology 1991;29(2):203-213
A statistical study of soldiers who visited the outpatient ciepartment of the Capital Armed Forces General Fiospital from 1987 to 1989 was performed. The results were as follows : 1. The total number of outpatients was 9969 with peak clinic visits in June(11.2%) and the lowest number of clinic visits in February(6.4% ). 2. The most frequent age was 22 years(20.7% ). Soldiers between 19 and 24 years old comprised 68.1% of total patients. 3. By rank 69.3% of the outpatients were private', 16.0% sergeant and 14,4% officers. 4. The most common dermatoses were dermatophytosis, contact dermatitis, scabies, acne, seborrheic dermatosis, urticaria, alopecia, condyloma acuminatum, verruca, folliculitis, psoriasis, insect bite reactions, pityriasis rosea, herpes zoster and corns. 5. Frequent diseases, which occured during summer season, included dermatophytosis, contact dermatitis and inser,t bites. The incidence of scabies, pityriasis prsea was increased during winter and that of psoriasis was increased during spring.
Acne Vulgaris
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Alopecia
;
Ambulatory Care
;
Arm
;
Callosities
;
Dermatitis, Contact
;
Folliculitis
;
Herpes Zoster
;
Humans
;
Incidence
;
Insect Bites and Stings
;
Military Personnel*
;
Outpatients
;
Pityriasis
;
Pityriasis Rosea
;
Psoriasis
;
Scabies
;
Seasons
;
Skin Diseases*
;
Statistics as Topic*
;
Tinea
;
Urticaria
;
Warts
;
Young Adult
;
Zea mays
4.A Case of Allergic Contact Dermatitis due to Lanolin.
Na La SHIN ; Yun Jin KIM ; Hyun Joo KIM ; Young Sook KIM ; So Yun CHO ; Jeong Hee HAHM
Korean Journal of Dermatology 1999;37(5):620-623
Lanolin is a complex material consisting of a mixture of numerous esters and polyesters of high-moleculer-weight alcohols and fatty acids, Lanolin allergy is important because lanolin is widely used as an emulsifier in topical medicaments and in numerous cosmetic preparations. We report a case of allergic contact dermatitis in a 27-year-old female. An erythematous pruritic rash develgood around the eyelid developed after applying a new eye cream and was aggravated after applying Cambison ophthalmic ointment. Patch testing showed positive reactions to Cambison ophthalmic ointment, 30% wool alcohol, Amerchol L101 and Nivea cream. A use test with 100% Cambison ophthalmic ointment base was positive
Adult
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Alcohols
;
Dermatitis, Allergic Contact*
;
Esters
;
Exanthema
;
Eyelids
;
Fatty Acids
;
Female
;
Humans
;
Hypersensitivity
;
Lanolin*
;
Patch Tests
;
Polyesters
;
Wool
5.Nursing Activities Identified through Pediatric Nursing Simulation.
Hyun Sook SHIN ; Ka Ka SHIM ; Yu Na LEE
Child Health Nursing Research 2013;19(2):111-119
PURPOSE: This research was a descriptive study of nursing activities observed in nursing simulation during a senior nursing student practicum. Content and frequencies of nursing activities during the simulation practice were identified. METHODS: Thirty-six episodes of pediatric nursing simulation were videotaped. Both verbalizations and descriptions of nonverbal behaviors were recorded from the videotapes. The data were coded and analyzed. The coded nursing activities were evaluated for frequency and purpose of interaction. RESULTS: Average time per simulation episodes was 27 minutes and ranged from 3.30 to 32.54 minutes. Nursing activities in these simulation episodes included nursing assessments such as vital sign measurement, associated symptom assessment, and check of patient condition, nursing interventions such as medication, tepid water massage, fluid therapy, provision of oxygen, suctioning, hyperglycemia and hypoglycemia management, communication such as parent education, procedure guidance, and communication among providers. Activities in assessment were most frequent, and among them, vital sign measurement and check of patient condition were more frequent than others. CONCLUSION: Students showed enhanced nursing activities such as more frequent nursing assessment, communication and interventions in their simulation experience. Therefore simulation experience can be considered as one strategies to provide nursing students with better and more intense practicum experience.
Education, Nursing
;
Fluid Therapy
;
Humans
;
Hyperglycemia
;
Hypoglycemia
;
Massage
;
Nursing Assessment
;
Oxygen
;
Parents
;
Patient Simulation
;
Pediatric Nursing
;
Students, Nursing
;
Suction
;
Symptom Assessment
;
Videotape Recording
;
Vital Signs
6.Early Results in Surgical Treatment of Thoracic Aortic Aneurysm.
Byoung Hee AHN ; Seong Hyeon SHIN ; Kook Joo NA
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(7):686-692
This study represents an attempt to present an analysis of early surgical results in 15 cases of aortic surgery conducted at Chonnam University Hospital between February 1994 to August 1995. The subject, 9 males and 6 females, ranged in age from 32 to 73 years with a mean age of 55.07+/-11.76 years. The patients were treated for dissecting aortic aneurysm in nine, atherosclerotic aneurysm in 4, and traumatic aortic aneurysm in two. There were 9 cases of median sternotomy, 4 cases of posterolateral thoracotomy, and 2 cases of thoracoabdominal incision. Graft replacement of ascending aorta and/or partial or total aortic arch were performed in 9 patients, descending aorta and/or thoracoabdominal aorta in 3 and total aorta in 1. Two traumatic aortic aneurysms were closed directly. Associate procedures were resuspension of aortic valve in three patients and elephant trunk procedure, coronary reimplantation and aortic valve replacement in one patient. Nine patients underwent operation for ascending aorta and/or aortic arch with retrograde cerebral perfusion during deep hypothermia and circulatory arrest. Perfusion pressure was maintained below 25 mmHg and the mean duration of circulatory arrest was 56.67+/-29.25 minutes. Three patients underwent graft replacement of desending thoracic and thoracoabdominal aorta during deep hypothermia and circulatory arrest. Three patients died of traumatic bile peritonitis, multioragn failure, and rupture of residual dissecting aortic aneurysm by malignant hypertension. Postoperative complications included reoperation for bleeding in 4 patients, temporary confusion in 3, pulmonary complication in 3, and pericardial effusion in 1.
Aneurysm
;
Aorta
;
Aorta, Thoracic
;
Aortic Aneurysm
;
Aortic Aneurysm, Thoracic*
;
Aortic Valve
;
Bile
;
Elephants
;
Female
;
Hemorrhage
;
Humans
;
Hypertension, Malignant
;
Hypothermia
;
Jeollanam-do
;
Male
;
Perfusion
;
Pericardial Effusion
;
Peritonitis
;
Postoperative Complications
;
Reoperation
;
Replantation
;
Rupture
;
Sternotomy
;
Thoracotomy
;
Transplants
7.Effects of Methylphenidate on Cognitive Impairment Following Brain Injury: A double-blind placebo-controlled study.
Yun Hee KIM ; Seung Yong NA ; Yong Il SHIN ; Jeong Hwan SEO
Journal of the Korean Academy of Rehabilitation Medicine 2000;24(4):611-627
OBJECTIVE: To evaluate the effect of methylphenidate on cognitive function especially on working memory and visuospatial attention in the patients with traumatic brain injury (TBI). METHOD: Eighteen subjects, 16 males and 2 females, with TBI were enrolled. Their mean age was 34.2 years old. A double-blind placebo-controlled study was designed. The baseline cognitive assessment was performed before the administration of drug. Two days after the baseline study, 20 mg of methylphenidate or placebo was administered. The second cognitive assessment was performed 2 hours after the treatment. The follow-up assessment conducted two days after the second test. Cognitive assessments consisted of 'one-back working memory task' and 'endogenous visuospatial attention task', designed using SuperLab Pro 2.0 software. RESULTS: In one-back working memory test, there was significant improvement of response accuracy in methylphenidate group in comparison with placebo group (p<0.01). Significant shortening of reaction time was also seen after the administration of drug in methylphenidate group (p<0.05). In endogenous visuospatial attention test, significant improvement of response accuracy was noticed after the administration of drug in methylphenidate group (p<0.05). CONCLUSION: These results demonstrated that the administration of methylphenidate was beneficial in improving cognitive function following TBI. The effect was prominent in the accuracy of working memory.
Brain Injuries*
;
Brain*
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Memory, Short-Term
;
Methylphenidate*
;
Reaction Time
8.Korean Housewives Living through Depression: A Grounded Theory Study.
Jeong Seop LEE ; Duck Shin SHIN ; Seon Hee CHOI ; Han Na KIM ; Kunsook S BERNSTEIN
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2014;23(4):217-225
PURPOSE: This study was conducted to generate theoretical constructs on depression from the study data by examining and interpreting Korean housewives' experience with depression to elicit its meaning, understand it better, and develop empirical knowledge on it. METHODS: The data were collected in a community public mental health center between April 1, 2012 and September 30, 2012 using in-depth interviews and theoretical sampling. The participants were 12 women aged 40-64 years who scored 7 or higher in the Korean version of the 21-item Hamilton Rating Scale for Depression (Kim, 1980). Collected data were analyzed by grounded theory methodology using open, axial, selective coding process. RESULTS: It was found that the basic socio-psychological process of Korean housewives' living through depression could be summarized into the following four phases: (1) the vanishing of the self into thin air, (2) becoming an empty shell, and (3) searching for the meaning of life, (4) fulfilling of an empty shell. CONCLUSION: This study may enhance the culturally elusive understanding of Korean housewives' experience with depression. As they are living through a hollow empty shell which looks normal on the outside, so can't get support from their families. It's important to educate their families about depressive phases.
Clinical Coding
;
Depression*
;
Female
;
Humans
;
Mental Health
;
Qualitative Research
9.Clinical study on therpeutic effects of Guided tissue regeneration by Nanogide-C(R) and Biomesh(R) in furcation defects.
Kyung Hee HAN ; Jong Won JUNG ; Ha Na HYUN ; Ji Man KIM ; Yun Sang KIM ; Sung Hee PI ; Hyung Shik SHIN
The Journal of the Korean Academy of Periodontology 2005;35(4):877-889
This study was designed to compare the effects of treatment using chitosan membrane (Nanogide-C(R)) resorbable barrier with control treated by polylactic acid/polylacticglycolic acid membrane(PLA/PLGA membrane, Biomesh(R)). 44 furcation defecs from 44 patients with class 2 furcation degree were used for this study, 22 sites of them were treated by chitosan membrane as experimental group and 22 site were treated by PLA/PLGA membrane as control group. Clinical parameters including probing depth, gingival recession, attachment level and radiographic examination were evlauated at base line, 1 month, 2 month and 3 month. after surgery. Statistical test used to analyze these data included paired t-test, one way ANOVA. The results are as follows : 1. Probing depth was significanlly decreased in the two group and there were significant differences between groups(p<0.05). 2. Gingival recession was not significanlly increased in the two group and there were no significant differences between groups(p<0.05). 3. Loss of attachment was statistically decreased in the two group and there were no significant differences between groups(p<0.05). 4. Horizontal bone level was significanlly increased in the two group and there were significant differences between groups(p<0.05). On the basis of these results, chitoans resorbable membrane has similar potential to PLA/PLGA membrane in GTR for furcation defect.
Chitosan
;
Furcation Defects*
;
Gingival Recession
;
Guided Tissue Regeneration*
;
Humans
;
Membranes
10.Dermal Stability and In Vitro Skin Permeation of Collagen Pentapeptides (KTTKS and palmitoyl-KTTKS).
Yun Lim CHOI ; Eun Ji PARK ; Eunje KIM ; Dong Hee NA ; Young Hee SHIN
Biomolecules & Therapeutics 2014;22(4):321-327
Collagen pentapeptide (Lys-Thr-Thr-Lys-Ser, KTTKS) and its palmitoylated derivative (pal-KTTKS) have received a great deal of attention as cosmeceutical ingredients for their anti-wrinkle effects. The objective of this study was to evaluate stability and permeability of KTTKS and pal-KTTKS in hairless mouse skin. In this study, a liquid chromatography-tandem mass spectrometric method was developed for the quantification of pal-KTTKS, and used for stability and permeability studies. Stability studies were performed using skin extracts and homogenates. Both KTTKS and pal-KTTKS were rapidly degraded, but pal-KTTKS was more stable than KTTKS. When protease inhibitors were added, the stability of both compounds (KTTKS and pal-KTTKS) improved significantly. In the skin permeation study, neither KTTKS nor pal-KTTKS was detected in the receptor solution, which indicates that neither compound could permeate through the full-thickness hairless mouse skin in the experimental conditions of this study. While KTTKS was not detected in any of the skin layers (the stratum corneum, epidermis, and dermis), pal-KTTKS was observed in all skin layers: 4.2 +/- 0.7 microg/cm2 in the stratum corneum, 2.8 +/- 0.5 microg/cm2 in the epidermis, and 0.3 +/- 0.1 microg/cm2 in the dermis. In conclusion, this study indicated that pal-KTTKS had greater stability and permeability than that of un-modified KTTKS, and may be a useful anti-wrinkle and anti-aging cosmeceutical agent.
Animals
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Collagen*
;
Dermis
;
Epidermis
;
Mice
;
Mice, Hairless
;
Permeability
;
Protease Inhibitors
;
Skin*