1.Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature.
So Hyang IM ; Dong Gyu KIM ; In Ae PARK ; Je G CHI
Journal of Korean Medical Science 2003;18(2):301-307
The authors present a case of primary intracranial extraosseous myxoid chondrosarcoma without any attachment to the cranium or the meninges. The clinical and radiological findings of the primary intraparenchymal tumor are described with a review of the literature concerning cranial and intracranial myxoid chondrosarcoma.
Adolescent
;
Adult
;
Bone Neoplasms/diagnosis*
;
Bone Neoplasms/pathology
;
Bone Neoplasms/surgery
;
Child
;
Chondrosarcoma/diagnosis*
;
Chondrosarcoma/pathology
;
Chondrosarcoma/surgery
;
Female
;
Human
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Myxosarcoma/diagnosis*
;
Myxosarcoma/pathology
;
Myxosarcoma/surgery
;
Tumor Markers, Biological
2.Primary Left Atrial Myxosarcoma: One case Report.
Cheul PARK ; Jong Seok KIM ; Yeon Jae LEE ; Han Yong KIM ; Byung Ha RYU ; Jong Kook KIM ; O Jun KWON ; Byung Heon KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2001;34(11):861-864
Primary cardiac myxosarcoma is extremely rare, which is uncommon in primary cardiac tumors. We report a primary cardiac myxosarcoma in a 40-year-old female patient who was admitted to the hospital because of exertional dyspnea and palpitation. The patient underwent emergency operation immediately after the intracardiac (left atrium) tumor was discovered by an echocardiography. Palliative tumor removal was done and final pathologic diagnosis was primary cardiac myxosarcoma. She was discharged without complications.
Adult
;
Diagnosis
;
Dyspnea
;
Echocardiography
;
Emergencies
;
Female
;
Heart Neoplasms
;
Humans
;
Myxoma
;
Myxosarcoma*
3.High Grade Myxofibrosarcoma in the Paravertebral Muscle: A Case Report.
Dong Hyuk NAM ; Tae Wan KIM ; Kwan Ho PARK ; Jae O KIM
Korean Journal of Spine 2010;7(4):268-271
Many different abnormalities, such as, neoplasm, infection, traumatic hematoma, or congenital or immune myopathy, may be found in the paravertebral muscles. However, neoplasms of paravertebral muscle are an uncommon cause of back pain. Such neoplasms may arise from local lesions or due to metastatic spread from a distant malignancy. The differential diagnoses of a primary soft tissue malignancy and metastatic spread from a skeletal muscle tumor are important. In cases of soft tissue sarcoma, histopathological findings and surgical margins are both related to local recurrence and metastasis, therefore, percutaneous needle biopsy may be helpful before surgical excision. A degree of surgical excision is decided based on considerations of muscular function and histopathological findings.
Back Pain
;
Biopsy, Needle
;
Diagnosis, Differential
;
Hematoma
;
Muscle, Skeletal
;
Muscles
;
Muscular Diseases
;
Myxosarcoma
;
Neoplasm Metastasis
;
Recurrence
;
Sarcoma
4.Primary myxoid liposarcoma of the pericardium.
Mei-fu GAN ; Hong-sheng LU ; Shou-xiang WENG ; Ju-fang CAI ; Wei-guang BAO
Chinese Journal of Pathology 2006;35(3):185-186
Adult
;
Diagnosis, Differential
;
Heart Neoplasms
;
metabolism
;
pathology
;
surgery
;
Humans
;
Immunohistochemistry
;
Liposarcoma, Myxoid
;
metabolism
;
pathology
;
surgery
;
Male
;
Myxoma
;
metabolism
;
pathology
;
Myxosarcoma
;
metabolism
;
pathology
;
Pericardium
;
S100 Proteins
;
metabolism
;
Vimentin
;
metabolism
5.Giant Cell Malignant Fibrous Histiocytoma of the Breast: A Case Report.
Se Jeong OH ; Kyoung Mee KIM ; Tae Ho HONG ; Woo Chan PARK ; Jeong Soo KIM ; Sang Seol JUNG
Journal of Korean Medical Science 2004;19(3):477-480
A case of primary malignant fibrous histiocytoma of the breast is reported. The patient was a 48-yr-old woman with a huge tumor involving almost the entire left breast. The central portion of her left breast was already rotted by extensive necrosis and inflammation. She was treated by radical mastectomy and axillary lymphadenectomy to level I. Pathologic examination supported by an immunohistochemical staining confirmed the tumor as malignant fibrous histiocytoma of giant cell type. Axillary lymph nodes were free from tumor metastasis. She had not taken any postoperative adjuvant therapy. The metastasis to lungs was found 2 months after the operation, and she died within 6 months.
Breast/pathology
;
Breast Neoplasms/*diagnosis/*pathology
;
Female
;
Giant Cells/*pathology
;
Histiocytoma, Fibrous/*diagnosis/*pathology
;
Human
;
Immunohistochemistry
;
Lung Neoplasms/mortality/secondary
;
Middle Aged
;
Myxosarcoma/diagnosis/pathology
;
Necrosis
;
Neoplasm Metastasis
;
Sarcoma/diagnosis/pathology
6.Myxofibrosarcoma and low-grade fibromyxoid sarcoma.
Chinese Journal of Pathology 2007;36(4):271-273
Cyclin E
;
metabolism
;
Dermatofibrosarcoma
;
pathology
;
Diagnosis, Differential
;
Fibrosarcoma
;
classification
;
metabolism
;
pathology
;
Humans
;
Ki-67 Antigen
;
metabolism
;
Liposarcoma
;
pathology
;
Myxoma
;
pathology
;
Myxosarcoma
;
metabolism
;
pathology
;
Proliferating Cell Nuclear Antigen
;
metabolism
;
Proto-Oncogene Proteins p21(ras)
;
metabolism
7.Acral myxoinflammatory fibroblastic sarcoma: report of a case.
Xiao-Hui WU ; Yong-Wei YU ; Yang WANG ; Yun LIN ; Ming-Hua ZHU
Chinese Journal of Pathology 2007;36(2):139-140
Adult
;
Diagnosis, Differential
;
Foot Diseases
;
metabolism
;
pathology
;
surgery
;
Humans
;
Immunohistochemistry
;
Male
;
Myxosarcoma
;
metabolism
;
pathology
;
surgery
;
Neoplasms, Muscle Tissue
;
pathology
;
Soft Tissue Neoplasms
;
metabolism
;
pathology
;
surgery
;
Tenosynovitis
;
pathology
;
Vimentin
;
metabolism
8.Mucoceles and mucocele-like lesions of breast.
Chinese Journal of Pathology 2009;38(9):633-636
Adenocarcinoma, Mucinous
;
pathology
;
Breast
;
pathology
;
Breast Diseases
;
pathology
;
Breast Neoplasms
;
pathology
;
Carcinoma, Papillary
;
pathology
;
Carcinoma, Signet Ring Cell
;
pathology
;
Cystadenocarcinoma, Mucinous
;
pathology
;
Diagnosis, Differential
;
Female
;
Fibroadenoma
;
pathology
;
Fibrosarcoma
;
pathology
;
Humans
;
Mucocele
;
pathology
;
Myxosarcoma
;
pathology
9.Myxoid Chondrosarcoma of the Sinonasal Cavity in a Child: a Case Report.
Yeo Ju KIM ; Soo Ah IM ; Gye Yeon LIM ; Ho Jong CHUN ; Hyun Jin PARK ; Min Sik KIM ; Yeong Jin CHOI
Korean Journal of Radiology 2007;8(5):452-455
Chondrosarcomas are malignant tumors of cartilage that rarely involve the sinonasal region, and myxoid chondrosarcoma is a rare histologic variant of chondrosarcoma that usually occurs in the soft tissue of extremities. Although several case reports and results of small series of chondrosarcomas in the sinonasal region in children are available, myxoid type chondrosarcoma is extremely rare. We recently experienced a case of low grade myxoid chondrosarcoma involving the sinonasal cavity in a 10-year-old boy, and here we report its radiologic-pathologic findings. In this case, chondroid calcification on CT and septal and marginal enhancement on MRI suggested a chondrosarcoma. Whole body PET-CT demonstrated no definite metastatic lesion and a low peak standardized uptake value primary tumor. However, no definite distinguishing imaging features were observed that distinguished low grade myxoid chondrosarcoma from conventional chondrosarcoma.
Bone Neoplasms/*diagnosis/radiotherapy/surgery
;
Child
;
Chondrosarcoma/*diagnosis/radiotherapy/surgery
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Myxosarcoma/*diagnosis/radiotherapy/surgery
;
Nasal Cavity/*pathology/*radiography/surgery
;
Paranasal Sinuses/*pathology/*radiography/surgery
;
Positron-Emission Tomography
;
Rare Diseases
;
Tomography, X-Ray Computed
;
Whole Body Imaging
10.Low-grade fibromyxoid sarcoma: a clinicopathological analysis of 9 cases.
Jun LIN ; Jian WANG ; Le-jun YU ; Xiang-lan YING
Chinese Journal of Pathology 2009;38(5):302-306
OBJECTIVETo study the clinicopathological features, immnophenotype and differential diagnosis of low-grade fibromyxoid sarcoma (LGFMS).
METHODSThe clinical, radiological and pathological features of 9 cases of LGFMS were reviewed.
RESULTSThe patients consisted of six males and three females with ages ranging from 11 to 65 years (mean 31.4 years). Clinically, most cases presented as slowly growing painless masses located in the extremities, trunk and neck. Two cases had a history of a rapid recent enlargement. Three cases presented with recurrent diseases after incomplete resection. Ultrasound showed heterogeneous signal. Precontrast CT and T1-weighted MRI showed a nodular mass of low to isodensity, while contrast-enhanced CT and T2-weighted MRI demonstrated contrasting zonal areas of hypo/hyperintensity. The tumors measured 3 to 16 cm (mean 7.7 cm), with a fibrous to myxoid appearance on cut surface. Histologically, they were composed of alternating collagenous and myxoid areas. A transition between the two areas could be identified. Giant rosette-like structures were observed in 3 cases. The center of the giant rosettes was composed of eosinophilic collagen, which showed centrifugal in arrangement. There was also gradual transition between the giant rosettes and the fibromyxoid component. On high magnification, the tumor was composed of ovoid to spindle-shaped cells with hyperchromatic nuclei. Nuclear atypia was inconspicuous. The tumor cells were arranged mostly in interlacing fascicles or whorls. Vessels were not prominent and necrosis was absent. Immunohistochemically, the tumor cells showed unique staining for vimentin, consistent with a fibroblastic differentiation.
CONCLUSIONSLGFMS is a distinctive low grade fibroblastic sarcoma of young adults. Recognizing the characteristics of the rare entity may help to avoid misdiagnosis. Wide local excision is recommended to avoid local recurrences.
Adolescent ; Adult ; Aged ; Child ; Diagnosis, Differential ; Extremities ; pathology ; Female ; Fibrosarcoma ; diagnosis ; metabolism ; pathology ; surgery ; Head and Neck Neoplasms ; diagnosis ; metabolism ; pathology ; surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myxosarcoma ; pathology ; Soft Tissue Neoplasms ; diagnosis ; metabolism ; pathology ; surgery ; Vimentin ; metabolism ; Young Adult