1.Surgical Repair of Giant Right Atrial Aneurysm in a Neonate.
Youngok LEE ; Joonyong CHO ; Gunjik KIM ; Sangbum LEE ; Myungchul HYUN ; Yeohyang KIM
Korean Circulation Journal 2011;41(6):331-333
Right atrial aneurysm is an extremity rare congenital heart defect. We report a case which was diagnosed during the early fetal stage and operated on in a 2 week old neonate. Following median sternotomy, aneurysmectomy was performed under a cardiopulmonary bypass. Histopathological examination of the resected atiral tissue showed a lipotomatous degeneration and reduction of the muscular elements. There were no postoperative complications.
Aneurysm
;
Cardiopulmonary Bypass
;
Extremities
;
Heart Aneurysm
;
Heart Atria
;
Heart Defects, Congenital
;
Humans
;
Infant, Newborn
;
Postoperative Complications
;
Sternotomy
2.First Case of Fungal Corneal Ulcer Caused by Pestalotiopsis mangiferae
Soongki ROH ; Myungchul SUH ; Hyun Chul LEE ; Won-Kil LEE ; Yu Kyung KIM
Laboratory Medicine Online 2020;10(3):247-249
Pestalotiopsis species are filamentous fungi that are known plant pathogens commonly isolated in tropical and subtropical regions. To the best of our knowledge, this is the first case of human infection caused by Pestalotiopsis mangiferae. An 80-year-old male farmer presented with ocular pain in the right eye. At initial presentation, slit-lamp examination showed a 3.0×2.5 mm-sized epithelial defect in the cornea of the right eye accompanied by corneal thinning. A KOH examination revealed spores, and consequently, treatment with voriconazole, ceftazidime, and moxifloxacin was initiated. One month later, a second KOH examination and fungal culture were performed. The results of the KOH examination indicated the presence of many hyphae, and fungus was isolated from the culture. Molecular identification revealed that the sequence had 100% similarity to P. mangiferae. The patient was treated with therapeutic penetrating keratoplasty. During follow-up in the outpatient clinic, signs of infection were not observed.
3.Factors Related to Regional Recurrence in Early Stage Squamous Cell Carcinoma of the Oral Tongue.
Soo youn AN ; Eun Jung JUNG ; Myungchul LEE ; Tack Kyun KWON ; Myung Whun SUNG ; Yoon Kyung JEON ; Kwang Hyun KIM
Clinical and Experimental Otorhinolaryngology 2008;1(3):166-170
OBJECTIVES: This study analyzed various clinical and histopathologic factors for patients with early stage squamous cell carcinoma (SCC) of the oral tongue to define a high risk group for regional recurrence and finally to find out the indication of elective neck dissection (END). METHODS: Retrospective chart review was performed for 63 patients with T1-T2N0 SCC of the oral tongue who underwent partial glossectomy with/without END. Clinical and histopathologic factors assessed were age, gender, clinical T stage, tumor cell differentiation, depth of invasion, pathologic nodal status, and intrinsic muscle involvement, perineural invasion, lymphovascular emboli and resection margin involvement. RESULTS: Five year overall survival rate was 97.1% in stage I and 76.2% in stage II, and 5-yr disease free survival rate was 76.7% in stage I and 43.5% in stage II. Rates of occult nodal metastasis in stage I and II were 15.4% and 42.9%, respectively. Overall regional recurrence rate was 15.9%, which consisted of 10.2% in stage I and 35.7% in stage II. The success rate of salvage treatment was 100% in stage I and 40% in stage II. Higher T stage, higher histologic grade, depth of invasion > or =3 mm, presence of intrinsic muscle involvement were significantly related to regional recurrence (P=0.035, P=0.011, P=0.016, P=0.009, respectively). In stage I, the non-END group (n=36) showed 13.9% of regional recurrence rate, while END group (n=13) did not have any regional recurrence (P=0.198). Five year disease free survival rate of END group was significantly higher than non-END group (100% and 68.7%, respectively, P=0.045). CONCLUSION: We recommend to perform END in early stage SCC of the oral tongue if the primary tumor has T2 stage, and T1 stage with higher histologic grade, depth of invasion more than 3 mm, or presence of intrinsic muscle involvement.
Carcinoma, Squamous Cell
;
Cell Differentiation
;
Disease-Free Survival
;
Glossectomy
;
Humans
;
Muscles
;
Neck Dissection
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Survival Rate
;
Tongue