1.A case of hepatic hydrothorax.
In Soo HONG ; Hak Suk YANG ; Ki Joon SUNG ; Myung Soon KIM
Korean Journal of Nuclear Medicine 1992;26(2):392-395
No abstract available.
Hydrothorax*
2.Microsatellite Instability and hMSH2 Gene Mutations in Sporadic Colorectal Cancers.
Hae Myung JEON ; Seung Tack OH ; Jeong Soo KIM ; Suk Kyun CHANG ; Jae Sung KIM
Journal of the Korean Society of Coloproctology 1998;14(1):41-49
Microsatellites are short nucleotide repeat sequences present throughout the human genome. Alterations of microsatellites, comprising extra or missing copies of these se quences, have been termed microsatellite instability(MSI, genetic instability, replication errors, RER(+) phenotype). To date, at least four genes involved in DNA mismatch repair, hMSH2, hMLH1, hPMS1 and hPMS2, are thought to account for the observation of microsatellite instability in tumor from Hereditary nonpolyposis colorectal cancer (HNPCC) patients. The genetic defect responsible for the MIN+ phenotype in sporadic colorectal cancer, however, has yet to be clearly delineated. The purpose of this study was to determine the presence of MSI in sporadic cancer and to correlate its occurrence with clinicopathological parameters, we have studied six microsatellite loci by use of polymerase chain reaction amplification and denaturing polyacrylamide gel electrophoresis. We found that 20%(9 of 46 cases) sporadic colorectal cancers showed RER at two or several loci(RER+). Microsatellite instability was associated with location of the tumor in the proximal colon 66%(6 of 9 cases) and with poorly differentiated tumor phenotype 56%(5 of 9 cases). In order to better understand the role of somatic alterations within hMSH2 in the process of colorectal tumorigenesis, we examined the most conserved regions(codon 598~789) of this gene in nine patients with MIN spotadic colorectal cancer. 6 patient of RER(+) colorectal ca. patients had a polymorphism which was a T to C base change in the intron sequence at -6 position of the splice acceptor site at the 5'end of exon 13. This particular sequence variation is a polymorphism rather than a mutation which increase cancer susceptability. These data suggest that the genetic instability is detect ed in some colorectal cancers and play an important role in the pathogenesis of sporadic colorectal cancer.
Carcinogenesis
;
Colon
;
Colorectal Neoplasms*
;
Colorectal Neoplasms, Hereditary Nonpolyposis
;
DNA Mismatch Repair
;
Electrophoresis, Polyacrylamide Gel
;
Exons
;
Genome, Human
;
Humans
;
Introns
;
Microsatellite Instability*
;
Microsatellite Repeats*
;
Phenotype
;
Polymerase Chain Reaction
;
RNA Splice Sites
3.A Study on Perception and Performance of Health Assessment among Clinical Nurses.
Journal of Korean Academy of Adult Nursing 2007;19(2):225-236
PURPOSE: The purpose of this study was to describe perception and performance of health assessment among clinical nurses. METHODS: The sample of this study consisted of 177 staff nurses working at university affiliated hospitals and a self-report questionnaire was used to collect data. Data were analyzed with SPSS WIN 12.0 program. RESULTS: The overall mean scores of perception and performance of health assessment were 3.67 and 1.71 respectively. There were no significant differences according to educational level, working department, and type of health assessment courses taken for perception of health assessment. The variable significantly affecting health assessment performance was the working department. There was a statistically significant correlation between perception and performance of health assessment. CONCLUSION: These findings suggest the need to develop a nursing education strategy to increase the performance of health assessment.
Education, Nursing
;
Surveys and Questionnaires
4.A clinical study on meconium-stained babies.
Cheol Ki MIN ; Sung Suk BANG ; Chong Young PARK ; Hae Ran LEE ; Choon Myung RO
Journal of the Korean Pediatric Society 1991;34(1):24-30
No abstract available.
Infant, Newborn
;
Meconium Aspiration Syndrome
5.An unusual reduplication of the ileum in adulthood.
Sung Bum HONG ; Myung Suk SIM ; Dong Youb SUH ; Dong Sun PARK ; Jin Kook KANG
Journal of the Korean Surgical Society 1992;42(1):135-139
No abstract available.
Ileum*
6.Fractures of the Carpal Scaphoid
Myung Chul YOO ; Dae Kyung BAE ; Jae Sung LEE ; Yong Suk JEON
The Journal of the Korean Orthopaedic Association 1983;18(5):999-1004
No abstract available in English.
7.Anterior Screw Fixation of Type II Odontoid Fracture.
Myung Jin KIM ; Jeong Hyun HWANG ; Joo Kyung SUNG ; Sung Kyu HWANG ; In Suk HAMM ; Yeun Mook PARK ; Seung Lae KIM
Journal of Korean Neurosurgical Society 2000;29(11):1461-1468
No abstract available.
8.Clinical efficacy of fluconazole in oropharyngeal and asophageal candidiasis.
Jong Dae JI ; Chul Won CHOI ; Goo LEE ; Jae Myung YOO ; Woo Joo KIM ; Jun Suk KIM ; Sung Shull PARK
Korean Journal of Infectious Diseases 1992;24(4):303-307
No abstract available.
Candidiasis*
;
Fluconazole*
9.Secondary Intraocular Lens Implantation in Pediatric Aphakia.
Uk Suk HWANG ; Sung Wook SEO ; Ji Myung YOO
Journal of the Korean Ophthalmological Society 1999;40(8):2167-2174
A retrospective study was done on secondary intraocular lens implantation in 19 children(22 eyes)who were not satisfied with aphakic glasses and were not tolerant with contact lenses.In all cases,postoperative visual acuity improved or remained at the preoperative level.In 10 cases,postoperative visual acuity was better than 20/40. After at least 12 months of follow-up,average difference of refractive power between the two eyes in the same patient is 0.79 diopter. Early postoperative complications related to secondary intraocular lens implantation were vitreous hemorrhage(1 eye)and IOL decentration. Vitreous hemorrhage was resorbed in three weeks.In case of IOL decentration,we repositioned the IOL.Late complcations during the follow-up period included development of dense capsular opacification in four eyes.They are all treated by Nd:YAG capsulotomy. After capsulotomy there were some improvement in visual acuity. From these results,secondary intraocular lens implantation appears to be a safe, effective method for correction of aphakic children who are not satisfied with aphakic glasses and/or intolerant of use of contact lenses.
Aphakia*
;
Child
;
Contact Lenses
;
Eyeglasses
;
Follow-Up Studies
;
Glass
;
Humans
;
Lens Implantation, Intraocular*
;
Lenses, Intraocular*
;
Postoperative Complications
;
Retrospective Studies
;
Visual Acuity
;
Vitreous Hemorrhage
10.Meconium as an Iron Source for the Growth of Staphylococcus Aureus in Amniotic Fluid.
Sung Heui SHIN ; Nam Woong YANG ; Myung Hee LEE ; Eun Woo LEE ; Eun Suk YANG ; Sang Kee PARK ; Yong LIM
Korean Journal of Perinatology 2000;11(3):335-342
No abstract available.
Amniotic Fluid*
;
Female
;
Iron*
;
Meconium*
;
Staphylococcus aureus*
;
Staphylococcus*