No abstract available.
Fetal Blood* ; Growth Hormone* ; Humans ; Infant, Newborn* ; Insulin-Like Growth Factor I* ; Somatomedins* ; Umbilical Cord*

It is notoriously difficult to obtain a sound bony union of congenital paeudarthrosis of tbe tibia with conventional methods. This paper is the results of using the free vascularized fibular graft for congenital pseudarthorsis of the tibia in 7 patients since 1978 in this hospital, which is the first attempt in Korea. During the follow-up periods from 9 months to 32 months, 5/7 patients(71%) had good or excellent bony union, 2 patients had bone resorption at tbe distal site of grafted bone and required a second supplementary cancellous bone graft with electrode insertion. So it is thought that the free vascularized fibular graft is one of good methods of treatment for congenital pseudarthrosis of the tibia.
Bone Resorption ; Electrodes ; Follow-Up Studies ; Humans ; Korea ; Pseudarthrosis ; Tibia ; Transplants

An arteriovenous fistula may be defined as a vascular abnormality in which there are one or more direct or indirect communication between an artery and a vein without any intervening capillary bed. Largely, such fistulas are divided into two groups-acquired (traumatic) or congenital in origin. There is a general agreement that congenital A-V fistula results from a failure in differentiation of the common embryonic anlage into true artery and vein. The authors have experienced a case of congenital A-V fistula formed in the 4th finger of the left hand. Such fistula is very difficult to excise completely with the conventional method. But we have obtained the excellent result by utilizing advanced meticulous microsurgical technique in excision.
Arteries ; Arteriovenous Fistula ; Capillaries ; Fingers ; Fistula ; Hand ; Methods ; Microsurgery ; Veins

In view of the problems with infection, traditional orthopedic teaching has held that the use of metalic fixation in open fractures is contraindicated. But the bone shortening and internal fixation of amputated limb is a principle for replantation. The authors experienced 23 patients of replanted limbs including femur, tibia, humerus, radius and ulnar among total 142 replantations and also analysed them in the respect of the relationship among soft tissue injury, fixatives, bone union and infection rate from February, 1975 to July, 1981 in this department. The rate of delayed union, nonunion and infection were 22.6%, 6.5% and 25.8% respectively. It seems that the union process of bone in replanted limbs is similar to that of the open fracture and also rigid internal fixation is the most useful for bony union.
Extremities ; Femur ; Fixatives ; Fractures, Open ; Humans ; Humerus ; Orthopedics ; Radius ; Replantation ; Soft Tissue Injuries ; Tibia

In vivo 31P NMR spectroscopic study of forearm wrist flexor muscles was performed in two groups of volunteers composed respectively of 6 sedentaries and 6 canoe athletes. A continuous isometric contraction of endurance exercises was adopted in oder to assess the endurance capacity and recovery potential of skeletal muscles. Differences in high energy phosphorus metabolism between the sedentaries and athletes were evaluated with and emphasis on the intracellular pH and Pi/PCr ratio as indicators of high energy phosphorus metabolism. There were no differences of baseline pH and Pi/PCr ratio between the two groups. The athletes sustained the exercise at more acidic intracellular pH and at a higher Pi/PCr ratio of intracellular conditions for an all-out than did the sedentaries. The recovery rate of pH showed no difference between the two groups. There was a tendency of faster recovery of Pi/PCr in athletes showing half recovery time(T1/2) of 39.0±3.0 seconds as compared to that of sedentaries (55.7±7.5 seconds). The recovery rate of Pi/PCr as a function of Pi/PCr ratio at a given period of time was significantly faster in athletes than in sedentaries (P<0.001). The correlation coefficient of the recovery rate of Pi/PCr against the Pi/PCr ratio was 0.985 and 0.914 respectively for the athletes and sedentaries. The pH and the Pi/PCR ratio at an all-out state can be used as indicators of endurance capacity and the recovery rate of Pi/PCr, as a reovery potential of skeletal muscles.
Athletes* ; Exercise ; Forearm ; Humans ; Hydrogen-Ion Concentration ; In Vitro Techniques* ; Isometric Contraction ; Metabolism ; Muscle, Skeletal* ; Muscles ; Phosphorus ; Volunteers ; Wrist

BACKGROUND: We could establish a streptonigrin-resistant strain called SR-1 strain from Staphylococcus aureus ATCC 6538 as a parental strain and characterize SR-1 strain as defective in the iron-uptake mechanisms including production of siderophores and expression of transferrin-binding protein on the cell wall. We performed this study to elucidate effect of the iron-uptake mechanisms on the growth in human body fluids. METHODS: Growth kinetics of SR-1 strain were compared with those of the parental strain and the increase of unsaturated iron-binding capacity (UIBC) was measured. Siderophore production and expression of transferrin-binding protein were detected by CAS diffusion assay and ligand-blot method probed with human transferrin conjugated horseradish peroxidase, respectively, as the strains were cultivated in normal pooled sera, ascitic fluid and pleural effusion. RESULTS: Siderophores activity in the body fluids could not be detected by the CAS diffusion assay. The parental strain expressed the transferrin-binding protein on the cell wall during the growth in ascites and pleural effusion except the sera whereas SR-1 strain did not. Growth kinetics showed that SR-1 strain grew sluggish compared to the parental strain. The peak of increase of UIBC of the parental strain was observed at the mid-exponential growth phase and the increase of UIBC of SR-1 strain was either lower than that of the parental strain or not changed. CONCLUSION: The iron-uptake mechanisms of S. aureus, especially expression of transferrin-binding protein, play a significant role in growing in the body fluids.
Ascites ; Ascitic Fluid ; Body Fluids ; Cell Wall ; Diffusion ; Horseradish Peroxidase ; Human Body* ; Humans* ; Iron* ; Kinetics ; Parents ; Pleural Effusion ; Siderophores ; Staphylococcus aureus* ; Staphylococcus* ; Streptonigrin ; Transferrin

No abstract available.
Amnion* ; Dinoprostone*

BACKGROUND: The effect of arterial carbon dioxide tension (PaCO2) during ischemia and reperfusion has been a controversial issue. In this study, the effect of PaCO2 during ischemia and reperfusion was evaluated by 31P magnetic resonance spectroscopy (MRS). METHODS: Incomplete global cerebral ischemia was induced by ligation of carotid artery under lowered mean blood pressure (mean blood pressure= 40 mmHg) for 30 minutes followed by 2 hours of reperfusion. Eighteen cats were divided into 3 groups: For group 1 (n=6) (control group), animals were subjected to normocarbia (PaCO2=28~33 mmHg) during ischemia and reperfusion, for group 2 (n=6), animals were subjected to hypocarbia (PaCO2=18~23 mmHg) during ischemia and reperfusion, and for group 3 (n=6), animals were subjected to normocarbia during ischemia and hypocarbia during reperfusion. RESULTS: For group 1, the energy metabolism measured by [PCr/Pi] was recovered about 74.7 6.4%. For group 2, the energy metabolism failed to be completely recovered by 120 minutes of reperfusion (69.3 7.3%), whereas for group 3, the energy matabolism was completely recovered by 120 minutes of reperfusion (97.6 2.4%). There were statistically significant differences between group 1 and group 3 (p<0.05). The changes in pH were not significantly different among the groups. CONCLUSION: In this study, a condition of hypocarbia during reperfusion seems better for the energy metabolism after incomplete global ischemia of cats.
Animals ; Blood Pressure ; Brain Ischemia ; Brain* ; Carbon Dioxide ; Carotid Arteries ; Cats* ; Energy Metabolism* ; Hydrogen-Ion Concentration ; Ischemia ; Ligation ; Magnetic Resonance Spectroscopy ; Reperfusion

OBJECTIVES: To test the neurodevelopmental hypothesis of the schizophrenia, we compared MR brain scans of schizophrenic patients with headache patients. METHOD: We conducted 7mm-slice magnetic resonance imaging study to evaluate the prevalence of CSF in a sample of 28 headache patients and 23 schizophrenic patients. All subjects are right-handed person by Annett's questionaires. RESULTS: Any size CSF was fecund 13/23(56.5%)schizophrenics and 16/28(57.1%) of headache patients. But larger CSF was found 26.1% of schizophrenics and 10.7% of headache patients. No statistically significant difference in gender and clinical subtype. CONCLUSIONS: Higher incidence of CSF in schizophrenic patients supports the hypothesis that anomalous development of the brain is an important aspect of the schizophrenia.
Brain ; Headache ; Humans ; Incidence ; Magnetic Resonance Imaging* ; Prevalence ; Schizophrenia*

No abstract available.
Amniotic Fluid* ; Female ; Iron* ; Meconium* ; Staphylococcus aureus* ; Staphylococcus*