1.A Case of Lichen Scrofulosorum.
Poong Myung KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1972;10(2):125-129
Lichen scrofulosorum, also known as Tuberculosis cutis lichenoides, is thought as a tuberculid such as Erythema induratum, Papulonecrotic tuberculid, Tuberculosis miliaris disseminata and Lupus miliaris disseminatus faciei. The lesions of Lichen scrofulosorum are pin-head sized or smaller, normal skin or reddish brown colored, arranged in nummular groups, usually on the trunk, where they persist unchanged or undergo spontaneous involution. As a rule, they appear in children who have tuberculosis of the bones or the lymphnodes. We report a case of Lichen scrofulosorum, 13-year old girl, who showed clinically and histologically typical lesions on the trunk. She was highly sensitive to Mantoux test and had tuberculous lymphadenitis of left cervical lymphnodes, but the chest was negative. Many challenges to the tuberculous origin of the tuberculids including Lichen scrofulosorum have prevailed for the last decade, Several studies and reports indicated that healing responses of Erythema induratum and other tuberculids to corticosteroids were more definite than to anti-tuberculosis drugs. But more recently, some reports recommended that anti-tuberculosis drugs were eftective than corticosteroids (in the treatment of Erythema induratum and other tuberculids). In this case anti-tuberculosis treatment with PAS 10gm., INH 400 mg., and streptomycin 1.0 gm. daily for the first one month and then 1.0gm. twice a week has remarkably improved the clinical manifestation in follow-up of three months. While the follow-up period was no enough, we strongly suggest the tuberculous origin of Lichen scrofulosorum.
Adolescent
;
Adrenal Cortex Hormones
;
Child
;
Erythema Induratum
;
Female
;
Follow-Up Studies
;
Humans
;
Lichens*
;
Skin
;
Streptomycin
;
Thorax
;
Tuberculosis
;
Tuberculosis, Cutaneous
;
Tuberculosis, Lymph Node
2.Clinical Evaluation of Dose Distribution in High Dose Rate Intracavitary Irradiation in the Treatment of Cervical Cancer.
Yeungnam University Journal of Medicine 1989;6(1):87-98
Clinical estimation of bladder and rectal doses from high dose rate intracavitary irradiation in carcinoma of the cervix uteri has been initiated on a routine basis in an effort to obtain the optimum radiotherapeutic dose. Simulation films with contrast media are used to image the bladder and rectum, and dose rates are estimated at various interesting points with the aid of treatment planning computer, NEC Therac-2300. Fifty-three patients have been reviewed in order to ascertain the correlation between radiation dose at interesting points in the bladder and rectum and the dose at Point A and B. The dose ratio between doses at Point A and interesting points in an important clinical factor in evaluating the treatment planning. This also serves as documentation of the dose to normal structures within the treatment volume. Authors conclude that obtained data are within acceptable ranges and routine simulation films of the bladder and rectum after administration of contrast media with dose calculations at interesting points provide important information for optimizing radiotherapy planning in the treatment of cervical carcinoma without increased time and effort or patient's discomfort.
Cervix Uteri
;
Contrast Media
;
Female
;
Humans
;
Radiotherapy
;
Rectum
;
Urinary Bladder
;
Uterine Cervical Neoplasms*
3.A study on dose distribution of small irradiation field in the electron therapy.
Sung Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1991;8(2):114-120
In electron therapy, low melting point alloy is used for shaping of the field. Electron field shaping material affect the output factor as well as the collimator system. The output factors of electron beams for shaped fields from NELAC-1018 were measured using ionization chamber of Farmer type in water phantom. The output factors of electron beams depend on the incident energy, inherent collimator system and the size of shaped field. Obtained results were followings. 1. In the smaller applicator, output varied extremely according to extent of collimator opening. 2. The higher energy, the output is less varied according to treatment field at small field.
Alloys
;
Farmers
;
Freezing
;
Water
4.The Dosimetry of Radiosurgery using of Rando Phantom.
Sung Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1990;7(1):113-119
The stereotactic radiosurgery using ionizing radiation of high energy is a technique for exadicating intracranial small tumors, which are inaccessible or unsuitable for open surgical technique. For such a small field radiosurgery, TLD or film dosimetry is essential. The three dimensional dose planning of radiosurgery was performed with dose planning computer system (Therac 2300). The target dose distribution and its error according to patient position were discussed. And were measured of circular cone which specially designed in our Hospital. The position error of Rando Phantom compared with CT were 0.4 mm in the AP-LAT section and in the AP-VERT section, 1.0 mm in the AP-VERT 45°section. The ratio of accuracy of the gantry and couch rotation were 1.5 mm diameter for central axis of 18MeV linear accelerator. Our study suggested that radiosurgery of small field in out department will be appropriate for clinical application.
Computer Systems
;
Film Dosimetry
;
Humans
;
Particle Accelerators
;
Radiation, Ionizing
;
Radiosurgery*
5.Effects of same TDF Factors on Body Weight of Mice and Peripheral Blood Picture.
Sei One SHIN ; Seong Gyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1987;4(2):89-96
Using same TDE factors, the authors studied the effects of whole abdominal irradiation on body weight and peripheral blood picture in 30±3 day old mice. Fractions of 100 and 200 cGy were given five times a week to the final TDF factors 17, 33, and 49. Total 80 mice were irradiated with orthovoltage x-ray machine. Our results can be summarized as follows: There were no significant differences by sex. Body weight was progressively decreased by the duration for irradiation, but no remarkable difference by fractional dose. Hemoglobin level showed no remarkable change by fractional dose or TDF factors. Leukopenic changes showed that severity of decrease seems to be more related to TDF factors. There were no significant changes of differential count by TDF factors of total doses.
Animals
;
Body Weight*
;
Dichlorodiphenyldichloroethane
;
Mice*
6.A Study on ARC Therapy of 18MeV Linear Accelerator.
Seong Kyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1988;5(2):31-36
In recent years there has been a growing interest in all forms of rotational therapy, and many different types of therapy machines designed for this kind of treatment have become available. To the medical radiation physicist, the dosimetry of rotation therapy has presented a number of interesting problems, and much useful work has been published on the basic date of dose distribution and dosage calculation. The setting dose for ARC therapy were obtained by computer calculation and measurement with cylindrical phantom. Authors compared computer calculation with measured value. And in ARC therapy, the region of maximum dose in shifted from the tumor center. The extent of shift was analyzed by isodose distribution for ARC therapy techniques.
Particle Accelerators*
7.Therapeutic Results of Radiotherapy in Nonsmall Cell Lung Cancers.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1994;11(1):72-81
Total 55 patients with nonsmall cell lung cancer treated with radiation therapy at Department of Therapeutic Radiology, Yeungnam University Hospital, between May-1 1986 and April-30 1993 were retrospectively analyzed by clinical characteristics, failure patterns follow up duration and survival ratio according to prognostic factors. Obtained results were as follows : 1. Male to female ratio was 17.3 2. Sixth and seventh decades were predominant age group. 3. The patients were 8 in stage I-II, 34 in stage IIIA, 13 in stage IIIb, respectively. 4. Forty five patients out of 55 were squamous cell carcinoma. 5. Primary tumor were originated from upper lobe bronchi predominantly. 6. The size of the primary tumor, lymph node involvement and the degree of differentiation were important in evaluation of prognosis. 7. In conclusion, for patients with poor prognostic factors systemic chemotherapy and multidisciplinary approach were recommended for better treatment outcome and improvement of survival.
Bronchi
;
Carcinoma, Non-Small-Cell Lung
;
Carcinoma, Squamous Cell
;
Drug Therapy
;
Female
;
Follow-Up Studies
;
Humans
;
Lung Neoplasms*
;
Lung*
;
Lymph Nodes
;
Male
;
Prognosis
;
Radiation Oncology
;
Radiotherapy*
;
Retrospective Studies
;
Treatment Outcome
8.A study of dose distribution in postoperative radiotherapy in uterine cervical cancer.
Sei One SHIN ; Sung Kyu KIM ; Myung Se KIM
Yeungnam University Journal of Medicine 1991;8(1):166-177
Uterine cervical cancer is the most common malignancy in Korean women. In spite of recent development of early diagnostic and therapeutic modalities, about 40% of treated patient will develop relapse. So more aggressive local treatment such as more extensive surgery and higher radiation dose and administration of systemic chemotherapy will promote the curability but treatment related complications cannot be avoidable. We used 22 cases of early cervical cancer, treated with surgery and post-operative radiotherapy, clinical data of these patients were analyzed to determine relationship between clinical parameters and final outcome. Three out of 22 cases revealed relapse and one patient showed rectovaginal fistula and another patient showed small bowel obstruction and the other patient showed rectal obstruction. Two out of three recurrence were stage IIa and the other one case was stage Ib adenocarcinoma with lymphovascular involvement. Nineteen out of 22 cases were followed without remarkable side effect or treatment related complication or sequelae. We concluded that out treatment policy was safe and effective to eradicate high risk postoperative cervical cancer with acceptable side effects or complication.
Adenocarcinoma
;
Drug Therapy
;
Female
;
Humans
;
Radiotherapy*
;
Rectovaginal Fistula
;
Recurrence
;
Uterine Cervical Neoplasms*
9.A Study on Equivalent Square Field in High Energy Photon Beam.
Seong Gyu KIM ; Sei One SHIN ; Myung Se KIM
Yeungnam University Journal of Medicine 1987;4(2):83-88
An analytic expression for equivalent square fields and a table are derived using the empirical representations obtained from the measured field size dependence of output for square field in a phantom. The expression is applicable to radiation fields that consistent with the following two assumptions imposed on these representations. 1) It is a linear function of the logarithm of the field area. 2) It is approximately the same function for both square and circular field of similar areas. In this paper, the derived tables and BJR table were consulted.
10.A Study on the dosimetry in boundary of shielding block in high energy irradiation.
Myung Se KIM ; Sung Kyu KIM ; Sei One SHIN
Yeungnam University Journal of Medicine 1990;7(2):115-120
Scatter-air ratios are used for the purpose of calculating scattered dose in the medium. The computation of the primary and the scattered dose separately is particularly useful in the dosimetry of irregular fields with shielding block in radiation field, dose distribution of scattered radiation using 18MeV Linear accelerator and Co-60 teletherapy measured. The effect of scattered radiation dose by protecting block was been ignored in radiation therapy, 2-3% of scattered radiation may be 90-200cGy which could be influence vital complication such as cataract, oligospermia or sterility. So that exact calculate scattered radiation by protecting block exactly for irregular field c small protection of vital organ is very important. The purpose of this article is to calculate scattered radiation by protecting block exactly for irregular field c Linac or Co-60 irradiation and to applicate these data in clinical radiation field. Authors could obtain following results. 1. The lesser angle between shielding block showed more scattered radiation. 2. With decreasing distance between shielding blocks, the dependent of scattered radiation were increased. 3. Output of 18 MeV Linear accelerator and Co-60 was related linear proportion on field size, but independent according to the size of shielding block in 18 MeV Linear accelerator.
Cataract
;
Infertility
;
Male
;
Oligospermia
;
Particle Accelerators